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Meanwhile, in Paris, Denis -- without proper citation -- had appropriated Lower's techniques and applied them to human transfusion. The Royal Society was outraged and Lower, sensitive to his colleagues' concerns, tried and succeeded at human transfusion. On 12 December 1667 the procedure was firmly established in England with

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“In the present state of our knowledge respecting the operation, although it has not been clearly shown to have proved

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http://www.armymedicine.army.mil/history/

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Sturli and DeCastello described the fourth blood group, AB, in 1902.

Levine and Stetson, in 1939, describe a severe reaction in aType O woman given a transfusion of her husband’s Type O

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More advances

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Preservation

ACD preservative was supplanted by citrate-phosphate-dextrose (CPD) in 1957, CPD with adenine in 1965, andCPD-A1 in the 1980s.

Effective preservation and refrigeration lead to the abilityto bank blood.

Cryoprotective agents, such as glycerol, gain use in the 1960s, enabling freezing of blood for long-term storage.

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