-

::A:4990G046:

()------ 3~4 ()------ 5~6 ------ 7~9 ------ 10~12 ------ 13~14 ------ 15 ------ 16

DNAmultiplex-PCRPCR-RFLP

(probe) DNAtarget

-RNA

DNAATGC pairs

DNA RNA DNA RNA DNAATGC pairs RNARNATUUTAU

RNA DNA DNA DNA RNARNA RNA RNA RNA DNA

Affymetrix(photolithography)

StanfordDNA

DNA4ATGC

http://proj1.sinica.edu.tw/~hispj/program/doc/97/20090516Wu_Shu_Hsing.pdfhttp://science.nchc.org.tw/old_science/j_TeacherLearn/document/A7970704.dochttp://ejournal.stpi.narl.org.tw/NSC_INDEX/Journal/EJ0001/9209/9209-12.pdfhttp://darwin.bio.uci.edu/~faculty/wagner/array2.html

http://darwin.bio.uci.edu/~faculty/wagner/array2.html

DNA cDNADNA DNA DNA DNA DNA DNA DNA DNA DNADNA DNA DNA

DNAexon intron introncDNAexon

DNADNA DNA

DNA DNA DNA DNA DNA DNADNADNA DNA DNA

DNAATGCATGCDNA(denature)DNADNAATTACGGC(reanneal)DNA(renature)DNA(probe)()DNA(target)mRNAcDNA

RNA

DNA DNA DNA