Transcript
  • (123)-1/35

    Acinetobacter baumannii

    AB

    carbapenem

    AB Carbapenem-resistant A. baumannii,

    CRAB

    CRAB colistin

    tigecyclinesulbactam

    minimum inhibitory concentrationMIC

    CRAB

    colistin tigecycline

    sulbactam carbapenem

    colistin tigecycline carbapenem

    Brosym cefoperazone 500

    mg sulbactam 500 mg

    Cefoperazone cephalosporins

    Sulbactam -lactamase

    cefoperazone cefoperazone

    AB Bacteroides penicillin

    binding proteinPBP

    Brosym

    CitrobactorKlebsiella

    EnterobactorSerratiaProteusPseudomonas

    Haemophilus influenza Acinetobacter

    Bacteroides

    Brosym CRAB

    randomized-controlled trial, RCT

    71 CRAB

    60

    cefoperazone/sulbactam 30

    73.3% 95.1% p

  • (123)-2/35

    1. Brosym

    2. Viehman JA, Nguyen MH, Doi Y. Treatment Options for

    Carbapenem-Resistant and Extensively Drug-Resistant Acinetobacter

    baumannii Infections. Drugs. 2014;74(12):1315-33.

    3. Xia J, Zhang D, Xu Y, Gong M, Zhou Y, Fang X. A retrospective analysis of

    carbapenem-resistant Acinetobacter baumannii-mediated nosocomial

    pneumonia and the in vitro therapeutic benefit of

    cefoperazone/sulbactam. Int J Infect Dis. 2014;23:90-3

    103 6 8 ADR

    1 Omnipaque 350 mg/ml, 200 ml/bot ( Iohexol ) (

    )

    2 Hyzaar 100 mg & 12.5 mg ( Losartan & hydrochlorthiazide )

    3 Cravit 250 mg/50 ml/vial ( Levofloxacin )

    4 Covina 2mg & 1mg/tab ( Estradiol & Norethindrone )

    5 Vidaza 100mg/vial ( Azacitidine )

    6 Cravit 250 mg/50 ml/vial ( Levofloxacin )

    7 Anbicyn 600 mg/vial ( Amoxicillin & Clavulanic Acid )

    Allopurinol 100 mg/tab

    8 PROPOFOL-LIPURO 200 mg/20 ml/amp ( Propofol )

    9 Celebrex 200mg/cap ( Celecoxib )

    ==

    FDA testosterone

    ( Food and Drug Administration, FDA )

    testosterone

    ( European Medicine Agency, EMA ) ( Health Canada )

    2014 1 2 testosterone

    FDA testosterone

    testosterone

    2014 6 FDA testosterone

    ( venous blood clots as a possible consequence of

    polycythemia )

    ( venous thromboembolism, VTE ) ( deep

    vein thrombosis, DVT ) ( pulmonary embolism, PE )

    Androgel Gel 5 g/pk ( Testosterone )

    Testosterone Cypionate 200 mg/ml/amp

    32973097

  • (123)-3/35

    ( 86/1/1 )

    1. Insulin

    2. CAPD

    3. CAPD

    4. Desferrioxamine Desferal

    5.

    20,000 U EprexRecormon 100 mcg AranespMircera(98/9/1)

    6. -interferon

    7. G-CSF ( filgrastimlenograstim( ( 98/11/1 )

    8. ( human growth hormone )

    9. ~ ( )

    86/9/192/5/1100/4/1 )

    10. ( TPN ) 85/10/193/12/1

    11. octreotidelanreotide ( SandostatinSomatuline ) octreotide

    ( Sandostatin ) ( 93/12/1 )lanreotide inj 30 mg ( Somatuline )

    ( 88/6/1 )octreotide LAR ( Sandostatin LAR Microspheres for Inj. ) ( 89/7/1 )

    12. streptomycinkanamycin enviomycin 86/9/1

    13. 87/4/1

    14.

    90/11/1

    15. Apomorphine hydrochloride 10mg/mL Apo-Go Pen

    on-and-off 20 91/2/199/11/1

    16. pernicious anemia B12 B12

    ( 91/4/1 )

    17. aldesleukin ( Proleukin Inj )

    ( 91/12/1 )

    18. B C

    ( 92/10/1 )

    19. etanerceptadalimumab

    (93/8/1)

    20. exenatide ( 103/9/1 )

    21. liraglutide ( 103/9/1 )

    22. teriparatide ( 103/9/1 )

    23. interferon beta-1a ( 103/9/1 )

    24. interferon beta-1b ( 103/9/1 )

    25. glatiramer ( 103/9/1 )

  • (123)-4/35

    Bydureon 2 mg/vial(Exenatide)

    Victoza 6 mg/ml, 3 ml/vial ( Liraglutide)

    Forteo 250 ug/ml, 2.4 ml/amp( Teriparatide )

    Rebif 44 mcg/12 MIU/vial ( Interferon beta-la )

    3.3.13. Agalsidase alfa agalsidase beta ( Replagal Infusion Fabrazyme Injection)

    ( 102/1/1103/9/1 )

    1.

    (1) alpha- galactosidase A alpha- galactosidase A

    I.

    II. ( Microalbuminuria)

    (2) ( Cardiac Variant )

    I. ( )

    ( )

    II. Cardiac Variant 1 9

    ( cardiac biopsy ) GL3 lyso-Gb3

    ( 103/9/1 )

    (I)III Cardiac Variant

    (II)IV

    2. Fabryzyme 1 mg/Kg/every 2 weeksReplagal 0.2 mg/Kg/every 2 weeks

    3. 1

    (1) MRI

    (2) MRI 10% 20%

    (3)

    (4)

    4.

    (1)

    (2) agalsidase alfa

    agalsidase beta

    (3) Cornea Verticillata

    5.

    (1) ( EGFR )

    (2) ( )

    (3) GL3

    (4) lyso-Gb3

    (5)

    (6)

    (7) (

  • (123)-5/35

    )

    (8) ( NYHA functional class 6 )

    (9)24 Holter :

    ()

    (10) ( MRI )

    Replagal 1 mg/ml,3.5 ml/vial ( Agalsidase alfa )

    9.26. Pemetrexed ( Alimta( 95/3/195/7/197/11/198/9/1103/4/1103/9/1 )

    1.

    (1) cisplatin

    (2) 70 ( )

    ( 95/7/197/11/198/9/1 )

    (3)

    ECOG performance status 0~1 ( 98/9/1 )

    2. 6 4

    103/4/1103/9/1

    Alimta 500 mg/vial ( Pemetrexed )

    Alimta 100 mg/vial ( Pemetrexed )

    9.47. lapatinib Tykerb103/9/1

    1. capecitabine anthracycline,taxane trastuzumab

    HER2

    2.

    Tykerb 250 mg/tab ( Lapatinib )

    8.2.4.Etanercept ( Enbrel ) ; adalimumab Humira ; golimumab Simponi

    abatacept Orenciatocilizumab Actemra( 92/3/193/8/193/9/198/3/1

    99/2/1100/12/1101/1/1101/6/1101/10/1102/1/1102/2/1102/4/1102/10/1

    103/9/1 )

    ( )

    103/9/1

  • (123)-6/35

    ENBREL 25mg/0.5ml/vial ( Etanercept )

    Humira 40 mg/vial ( Adalimumab )

    Simponi 50 mg/0.5 ml/vial ( Golimumab )

    Abatacept ( Orencia ) 250 mg/vial

    Actemra ( Tocilizumab ) 80 mg/4 ml/vial

    Actemra ( Tocilizumab ) 200 mg/10 ml/vial

    9.20.Rituximab ( Mabthera) (91/4/193/1/195/3/197/2/1102/1/1103/2/1

    103/9/1 )

    1. B ( 91/4/1 )

    2. CHOP CD20 B ( 93/1/195/3/1 )

    3. CVP B ( 95/3/1 )

    4.

    ( 97/2/1 )

    5. ( 103/2/1 )

    (1) Rai Stage / ( Binet C ) CLL Rai Stage / ( Binet A/B )

    ()

    CD20 50%

    (2) CD20 CD20

    50%

    (3)

    6. ( ANCA ) ( 103/9/1 )

    (1)

    (2) cyclophosphamide 4

    (3) ( GPA Wegeners granulomatosis )

    ( MPA ) cyclophosphamide

    (4) cyclophosphamide

    (5) 4

    ( ) cyclophosphamide 4

    cyclophosphamide 4 :

    A

    B

    C

    D

    7. 14 5 6 ( 102/1/1103/2/1103/9/1 )

    Mabthera 100 mg/10 ml/vial ( Rituximab )

    Mabthera 500 mg/50 ml/vial ( Rituximab )

  • (123)-7/35

    103 08

    Generic Name

    Brand Name

    /

    Appearance

    /

    Use

    Caution

    Pramipexole

    0.375 mg/tab

    Mirapex PR

    ( )

    025258

    /

    P1/

    ( 1030801 )

    20.2

    Ciclesonide

    160 mcg/dose ;

    60 doses/ bot

    Alvesco 160 Inhaler

    ( )

    024786

    /

    ( 1030805 )

    524

  • (123)-8/35

    Generic Name

    Brand Name

    /

    Appearance

    /

    Use

    Caution

    Crizotinib

    250 mg/cap

    Xalkori

    ( )

    025938

    / pfizer CRZ250

    ALK

    ALK

    ( 1030801 )

    4153

    Macitentan

    10 mg/tab

    Opsumit

    ( Patheon Italia )

    / 10

    WHO II

    IV

    ( 1030807 )

    3784

  • (123)-9/35

    103 08

    Generic Name

    Before New /

    Use

    Caution

    Brand Name

    /

    Appearance

    Brand Name

    /

    Appearance

    Ceftazidime

    1 g/vial

    Cetazine

    ( )

    041754

    / Sintum

    ( )

    042091

    / Ceftazidime

    ( 1030807 )

    72

    Folic Acid

    5 mg/tab

    Folic Acid

    ( )

    007543

    /

    124/

    Folacin

    ( )

    034670

    /

    ( 1030809 )

    2

  • (123)-10/35

    Generic Name

    Before New /

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    /

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    Brand Name

    /

    Appearance

    Procaterol

    25 mcg /tab

    Pocathma- Mini

    ( )

    045416

    /

    S T/273

    Meptin-Mini

    ( )

    043700

    /

    OG/22

    ( 1030809 )

    2

    Montelukast

    10 mg/tab

    Singulair

    ( )

    022778

    /

    SINGULAIR/

    MSD 117

    Anxokast

    ( )

    047813

    /

    AX 010

    ( ALLERGIC RHINITIS )

    ( 1030809 )

    25.6

  • (123)-11/35

    Generic Name

    Before New /

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    /

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    Brand Name

    /

    Appearance

    Dipyridamole

    25 mg/tab

    Solantin

    ( )

    032530

    /

    Dipyridamole

    ( )

    013801

    /

    STD 129

    ( 1030811 )

    2

    Levothyroxine

    100 mcg/tab

    Eltroxin

    ( GSK )

    024708

    /

    GS 21C/100

    Thyroid-S

    ( )

    048191

    /

    /

    ( 1030811 )

    2

  • (123)-12/35

    Generic Name

    Before New /

    Use

    Caution

    Brand Name

    /

    Appearance

    Brand Name

    /

    Appearance

    Clarithromycin

    500 mg/tab

    Klaricid

    ( )

    022420

    /

    e

    Klarith

    ( )

    046638

    /

    PBF436

    OMEPRAZOLE

    ( H.

    PYLORI )

    ( 1030812 )

    25.1

    Meclizine

    25 mg/tab

    Semper

    ( )

    034272

    /

    148/

    Meclizine

    ( )

    004781

    /

    FY T069

    ( 1030812 )

    0.66

  • (123)-13/35

    Generic Name

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    /

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    Brand Name

    /

    Appearance

    Disterile Water

    1000 mL/bot

    Water for inj

    ( )

    032379

    / Water for inj

    ( )

    003133

    /

    ( 1030813 )

    33.75

    Fludiazepam

    0.25 mg/tab

    Flupine

    ( )

    041519

    /

    G 38/JCP

    Erispan

    ( )

    009391

    /

    017

    ( 1030813 )

    2.86

  • (123)-14/35

    Generic Name

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    /

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    Brand Name

    /

    Appearance

    Albumin 20%

    10 g/ 50mL/bt

    Plasbumin-20

    ( )

    000777

    / Albumin

    ( TBSF )

    000842

    /

    ( 1030813 )

    1212

    Ramipril

    10 mg/tab

    Tritace

    ( )

    023603

    /

    HMO HMO

    Syntace

    ( )

    051029

    /

    SY/11

    ( 1030813 )

    10.5

  • (123)-15/35

    Generic Name

    Before New /

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    Brand Name

    /

    Appearance

    Brand Name

    /

    Appearance

    Amoxicillin &

    Clavulanate

    Potassium

    500 mg &

    100 mg/ vial

    Anbicyn

    ( )

    042697

    / Augmentin

    ( )

    018304

    /

    ( 1030814 )

    56

    Prednisolone

    5 mg/tab

    Donison

    ( )

    002531

    /

    CCP C03

    Compesolon

    ( )

    031676

    /

    PLt

    (1030814 )

    2

  • (123)-16/35

    Generic Name

    Before New /

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    Brand Name

    /

    Appearance

    Brand Name

    /

    Appearance

    Allopurinol

    100 mg/tab

    Allopurinol

    ( )

    014228

    /

    YUNG SHIN

    Urinol

    ( )

    020894

    /

    ( 1030814 )

    2

    Lubricant K-Y Jelly

    ( )

    000852

    /

    82 gm/tube

    Water Gel

    ( )

    001229

    /

    82 mL/tube

    ( 1030815 )

    144

  • (123)-17/35

    Generic Name

    Before New /

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    Brand Name

    /

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    Brand Name

    /

    Appearance

    Cefepime

    Maxipime

    ( )

    021777

    /

    500 mg/vial

    Cefim

    ( )

    048834

    /

    1000 mg/vial

    Cefepime

    :

    Maxipime

    500 mg/vial,

    Cefim 1000

    mg/vial

    (1030815 )

    432

    Fexofenadine

    60 mg/tab

    Fexofenadine

    ( )

    057127

    /

    CC P/138

    Allegra

    ()

    023016

    /

    06

    (1030814 )

    3.33

  • (123)-18/35

    Generic Name

    Before New /

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    /

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    Brand Name

    /

    Appearance

    Mirtazapine

    30 mg/tab

    Remeron

    ( )

    024009

    /

    TZ 2

    Mirtapine

    ( )

    049656

    /

    PLT33/MTZ

    ( 1030815 )

    23.5

    Pyridostigmine

    60 mg/tab

    Mestinon

    ( )

    036008

    /

    Antilon

    ( )

    048908

    /

    PR/

    ( 1030815 )

    3

  • (123)-19/35

    Generic Name

    Before New /

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    Brand Name

    /

    Appearance

    Brand Name

    /

    Appearance

    Cimetidine

    300 mg/tab

    Defense

    ( )

    22836

    /

    C

    Stogamet

    ( )

    038419

    /

    SPC/S86

    ( 1030816 )

    2

    Nicorandil

    5 mg/tab

    Sigmart

    ( )

    020991

    /

    C-21F 5

    Nirandil

    ( )

    048991

    /

    ST/1001

    ( 1030818 )

    4.82

  • (123)-20/35

    Generic Name

    Before New /

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    Brand Name

    /

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    Brand Name

    /

    Appearance

    Cephradine

    1 g/vial

    S-60

    ( )

    033149

    / Lofadine

    ( )

    029504

    /

    ( 1030818 )

    28.4

    Tramadol &

    Acetaminophen

    37.5 mg &

    325 mg/tab

    Ultracet

    ( )

    023917

    /

    JANSSEN/T/A

    Tramacet

    ( )

    057779

    /

    UC75

    ( 1030818 )

    7.4

  • (123)-21/35

    Generic Name

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    Brand Name

    /

    Appearance

    Hydrocortisone Na

    Succinate

    100 mg/ vial

    Hydrocortisone

    ( )

    057749

    / Solu-Cortef

    ( )

    018167

    /

    ( 1030818 )

    35.3

    Trihexyphenidyl

    2 mg/tab

    Benzox

    ( )

    038846

    /

    L

    Switane

    ( )

    039597

    /

    SWISS 2

    ( 1030818 )

    1.5

  • (123)-22/35

    Generic Name

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    /

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    Brand Name

    /

    Appearance

    Aceclofenac

    100 mg/tab

    Tonec

    ( )

    046613

    /

    UC 25

    Ascofen

    ( )

    057798

    /

    STD/777

    ( 1030818 )

    6

    Diltiazem

    30 mg / tab

    Diltisser

    ( )

    033224

    /

    CCP

    Cartil

    ( )

    036966

    /

    SYG30

    ( 1030819 )

    2

  • (123)-23/35

    Generic Name

    Before New /

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    Brand Name

    /

    Appearance

    Brand Name

    /

    Appearance

    Cetirizine

    10 mg/tab

    Cety

    ( )

    044710

    /

    YSP38

    Cemine

    ( )

    043403

    /

    SC/C18

    ( 1030819 )

    2

    Mephenoxalone

    200 mg/tab

    Doflex

    ( )

    042919

    /

    GP/277

    Mefno

    ( )

    043257

    /

    OB 02

    ( 1030819 )

    2

  • (123)-24/35

    Generic Name

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    /

    Appearance

    Sodium Chloride

    0.9%500 mL/bot

    Saline

    ( )

    029836

    / Sodium Chloride

    ( )

    009997

    / ( 1030819 )

    25

    Azathioprine

    50 mg/tab

    Azathioprine

    ( )

    022229

    /

    AZP 50

    Azamun

    ( )

    025754

    /

    AZA50

    ( 1030820 )

    18

  • (123)-25/35

    Generic Name

    Before New /

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    /

    Appearance

    Brand Name

    /

    Appearance

    Rocuronium

    50 mg/5 mL/vial

    Esmeron

    ( )

    022140

    / Rocurin

    ( )

    052611

    /

    ( 1030820 )

    307.5

    Metformin

    500 mg/tab

    Loditon

    ( )

    043706

    /

    STD/L 09

    Uformin

    ( )

    036349

    /

    MF1

    ( 1030820 )

    2

  • (123)-26/35

    Generic Name

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    /

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    Phenytoin

    100 mg

    Dilantin

    ( )

    00817

    /

    /

    PARKE/PD100

    Aleviatin

    ( )

    002320

    /

    Ptsh/

    ( 1030820 )

    2

    Atorvastatin

    40 mg/tab

    Lipitor

    ( )

    022889

    /

    PD 157/40

    Atorva

    ( )

    055268

    /

    STD/290

    ( 1030820 )

    35

  • (123)-27/35

    Generic Name

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    /

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    /

    Appearance

    Zoledronic Acid

    4 mg/vial

    Zometa

    ( )

    023733

    / Zobonic

    ( )

    055020

    /

    ( HCM )

    ( 1030820 )

    10928

  • (123)-28/35

    Generic Name

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    Enalapril

    20 mg/tab

    Sintec

    ( )

    039414

    /

    ST/

    Enalatec

    ( )

    039401

    /

    CCP/

    ( 1030820 )

    2

    Dextromethor-

    phan HBr

    60 mg/S.R.tab

    Detosiv

    ( )

    044781

    /

    LO/06

    Regrow

    ( )

    042687

    /

    ( 1030821 )

    2.8

  • (123)-29/35

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    Pilocarpine

    2% 15 mL/bot

    Pilocarpine

    ( )

    032283

    /

    Isopto Carpine

    ( )

    016483

    /

    ( 1030821 )

    83

    Fenofibrate

    160 mg/tab

    Lipanthyl

    ( )

    023770

    /

    160/

    Fenolip-U

    ( )

    047228

    /

    CH/60

    ( TYPE IIaIIbIIIIVV )

    ( 1030822 )

    7.4

  • (123)-30/35

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    Polycresolsulf-

    onate & Cinchocaine

    100 mg &

    2.5 mg/ Supp.

    Ebodyl

    ( )

    047550

    / Posuline

    ( )

    047029

    /

    ( 1030822 )

    9.4

    Calcium Gluconate Glucal Black

    ( )

    005603

    /

    20%

    5 mL/amp [Ca

    =0.898

    mEq/mL]

    Calglon

    ( )

    058006

    /

    10%

    10 mL/amp

    [Ca = 0.465

    mEq/mL]

    Calglon

    Glucal Black

    ( 1030822 )

    12.5

  • (123)-31/35

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    Sevoflurane

    250 mL/bt

    Sevoflurane

    ( BAXTER )

    024308

    / Ultane

    ( Aesica )

    022836

    /

    Sevoflurane

    ( 1030822 )

    3516

    .

  • (123)-32/35

    Generic Name

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    Ampicillin &

    Sulbactam

    1.5 g/vial

    Subacillin

    ( )

    046544

    /

    Sulampi

    ( )

    052553

    /

    ( Bacteroides,

    Fusobacterium,

    Clostridium difficile )

    Branhamella catarrhalis

    (1030822 )

    108

  • (123)-33/35

    103 08

    Generic Name

    Brand Name

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    /

    Use

    Caution

    Pramipexole

    0.25 mg/tab

    Mirapex

    ( )

    023280

    /

    P7 P7/

    ( PRIMARY RESTLESS LEGS

    SYNDROME )

    :

    Mirapex PR

    0.375 mg/tab ( Pramipexole)

    Mirapex

    0.25mg/tab ( Pramipexole )

    ( 1030801 )

    12.8

    Fluticasone 250mcg/dose ;

    60 doses/bot

    Flixotide Accuhaler

    ( )

    021921

    / :

    Alvesco inhaler

    160mcg/dose 60doses

    ( Ciclesonide )

    Flixotid Accuhaler

    250ug/dose 60dose/bt

    ( Fluticasone )

    ( 1030805 )

    516

  • (123)-34/35

    Generic Name

    Brand Name

    /

    Appearance

    /

    Use

    Caution

    Ornithine Aspartate

    250 mg/cap

    Hepacure

    ( )

    015826

    /

    ( 1030809 )

    720

    Haloperidol

    mg/drop

    30 mg/15 mL/bot

    Haldomin

    ( )

    030383

    /

    : Paliperidone

    ( Invega sustenna 100mg/vial

    & 150mg/vial )

    Haldomin

    ( 1030809 )

    :

    1. Haloperidol ( Binin-U ) 5

    mg/tab

    2. Haloperidol ( Binin-U ) 5

    mg/mL/amp

    45.5

  • (123)-35/35

    Generic Name

    Brand Name

    /

    Appearance

    /

    Use

    Caution

    Hyaluronic acid

    16 mg/2 mL/syringe

    Synvisc

    ( )

    010770

    /

    ACETAMINOPHEN

    ( 1030819 )

    :

    Hyaluronic acid ( ArtiAid )

    25 mg/2.5 mL/amp

    Hyaluronic acid ( Hya-Joint )

    25 mg/2.5 mL/amp

    6600


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