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(123)-1/35
Acinetobacter baumannii
AB
carbapenem
AB Carbapenem-resistant A. baumannii,
CRAB
CRAB colistin
tigecyclinesulbactam
minimum inhibitory concentrationMIC
CRAB
colistin tigecycline
sulbactam carbapenem
colistin tigecycline carbapenem
Brosym cefoperazone 500
mg sulbactam 500 mg
Cefoperazone cephalosporins
Sulbactam -lactamase
cefoperazone cefoperazone
AB Bacteroides penicillin
binding proteinPBP
Brosym
CitrobactorKlebsiella
EnterobactorSerratiaProteusPseudomonas
Haemophilus influenza Acinetobacter
Bacteroides
Brosym CRAB
randomized-controlled trial, RCT
71 CRAB
60
cefoperazone/sulbactam 30
73.3% 95.1% p
(123)-2/35
1. Brosym
2. Viehman JA, Nguyen MH, Doi Y. Treatment Options for
Carbapenem-Resistant and Extensively Drug-Resistant Acinetobacter
baumannii Infections. Drugs. 2014;74(12):1315-33.
3. Xia J, Zhang D, Xu Y, Gong M, Zhou Y, Fang X. A retrospective analysis of
carbapenem-resistant Acinetobacter baumannii-mediated nosocomial
pneumonia and the in vitro therapeutic benefit of
cefoperazone/sulbactam. Int J Infect Dis. 2014;23:90-3
103 6 8 ADR
1 Omnipaque 350 mg/ml, 200 ml/bot ( Iohexol ) (
)
2 Hyzaar 100 mg & 12.5 mg ( Losartan & hydrochlorthiazide )
3 Cravit 250 mg/50 ml/vial ( Levofloxacin )
4 Covina 2mg & 1mg/tab ( Estradiol & Norethindrone )
5 Vidaza 100mg/vial ( Azacitidine )
6 Cravit 250 mg/50 ml/vial ( Levofloxacin )
7 Anbicyn 600 mg/vial ( Amoxicillin & Clavulanic Acid )
Allopurinol 100 mg/tab
8 PROPOFOL-LIPURO 200 mg/20 ml/amp ( Propofol )
9 Celebrex 200mg/cap ( Celecoxib )
==
FDA testosterone
( Food and Drug Administration, FDA )
testosterone
( European Medicine Agency, EMA ) ( Health Canada )
2014 1 2 testosterone
FDA testosterone
testosterone
2014 6 FDA testosterone
( venous blood clots as a possible consequence of
polycythemia )
( venous thromboembolism, VTE ) ( deep
vein thrombosis, DVT ) ( pulmonary embolism, PE )
Androgel Gel 5 g/pk ( Testosterone )
Testosterone Cypionate 200 mg/ml/amp
32973097
(123)-3/35
( 86/1/1 )
1. Insulin
2. CAPD
3. CAPD
4. Desferrioxamine Desferal
5.
20,000 U EprexRecormon 100 mcg AranespMircera(98/9/1)
6. -interferon
7. G-CSF ( filgrastimlenograstim( ( 98/11/1 )
8. ( human growth hormone )
9. ~ ( )
86/9/192/5/1100/4/1 )
10. ( TPN ) 85/10/193/12/1
11. octreotidelanreotide ( SandostatinSomatuline ) octreotide
( Sandostatin ) ( 93/12/1 )lanreotide inj 30 mg ( Somatuline )
( 88/6/1 )octreotide LAR ( Sandostatin LAR Microspheres for Inj. ) ( 89/7/1 )
12. streptomycinkanamycin enviomycin 86/9/1
13. 87/4/1
14.
90/11/1
15. Apomorphine hydrochloride 10mg/mL Apo-Go Pen
on-and-off 20 91/2/199/11/1
16. pernicious anemia B12 B12
( 91/4/1 )
17. aldesleukin ( Proleukin Inj )
( 91/12/1 )
18. B C
( 92/10/1 )
19. etanerceptadalimumab
(93/8/1)
20. exenatide ( 103/9/1 )
21. liraglutide ( 103/9/1 )
22. teriparatide ( 103/9/1 )
23. interferon beta-1a ( 103/9/1 )
24. interferon beta-1b ( 103/9/1 )
25. glatiramer ( 103/9/1 )
(123)-4/35
Bydureon 2 mg/vial(Exenatide)
Victoza 6 mg/ml, 3 ml/vial ( Liraglutide)
Forteo 250 ug/ml, 2.4 ml/amp( Teriparatide )
Rebif 44 mcg/12 MIU/vial ( Interferon beta-la )
3.3.13. Agalsidase alfa agalsidase beta ( Replagal Infusion Fabrazyme Injection)
( 102/1/1103/9/1 )
1.
(1) alpha- galactosidase A alpha- galactosidase A
I.
II. ( Microalbuminuria)
(2) ( Cardiac Variant )
I. ( )
( )
II. Cardiac Variant 1 9
( cardiac biopsy ) GL3 lyso-Gb3
( 103/9/1 )
(I)III Cardiac Variant
(II)IV
2. Fabryzyme 1 mg/Kg/every 2 weeksReplagal 0.2 mg/Kg/every 2 weeks
3. 1
(1) MRI
(2) MRI 10% 20%
(3)
(4)
4.
(1)
(2) agalsidase alfa
agalsidase beta
(3) Cornea Verticillata
5.
(1) ( EGFR )
(2) ( )
(3) GL3
(4) lyso-Gb3
(5)
(6)
(7) (
(123)-5/35
)
(8) ( NYHA functional class 6 )
(9)24 Holter :
()
(10) ( MRI )
Replagal 1 mg/ml,3.5 ml/vial ( Agalsidase alfa )
9.26. Pemetrexed ( Alimta( 95/3/195/7/197/11/198/9/1103/4/1103/9/1 )
1.
(1) cisplatin
(2) 70 ( )
( 95/7/197/11/198/9/1 )
(3)
ECOG performance status 0~1 ( 98/9/1 )
2. 6 4
103/4/1103/9/1
Alimta 500 mg/vial ( Pemetrexed )
Alimta 100 mg/vial ( Pemetrexed )
9.47. lapatinib Tykerb103/9/1
1. capecitabine anthracycline,taxane trastuzumab
HER2
2.
Tykerb 250 mg/tab ( Lapatinib )
8.2.4.Etanercept ( Enbrel ) ; adalimumab Humira ; golimumab Simponi
abatacept Orenciatocilizumab Actemra( 92/3/193/8/193/9/198/3/1
99/2/1100/12/1101/1/1101/6/1101/10/1102/1/1102/2/1102/4/1102/10/1
103/9/1 )
( )
103/9/1
(123)-6/35
ENBREL 25mg/0.5ml/vial ( Etanercept )
Humira 40 mg/vial ( Adalimumab )
Simponi 50 mg/0.5 ml/vial ( Golimumab )
Abatacept ( Orencia ) 250 mg/vial
Actemra ( Tocilizumab ) 80 mg/4 ml/vial
Actemra ( Tocilizumab ) 200 mg/10 ml/vial
9.20.Rituximab ( Mabthera) (91/4/193/1/195/3/197/2/1102/1/1103/2/1
103/9/1 )
1. B ( 91/4/1 )
2. CHOP CD20 B ( 93/1/195/3/1 )
3. CVP B ( 95/3/1 )
4.
( 97/2/1 )
5. ( 103/2/1 )
(1) Rai Stage / ( Binet C ) CLL Rai Stage / ( Binet A/B )
()
CD20 50%
(2) CD20 CD20
50%
(3)
6. ( ANCA ) ( 103/9/1 )
(1)
(2) cyclophosphamide 4
(3) ( GPA Wegeners granulomatosis )
( MPA ) cyclophosphamide
(4) cyclophosphamide
(5) 4
( ) cyclophosphamide 4
cyclophosphamide 4 :
A
B
C
D
7. 14 5 6 ( 102/1/1103/2/1103/9/1 )
Mabthera 100 mg/10 ml/vial ( Rituximab )
Mabthera 500 mg/50 ml/vial ( Rituximab )
(123)-7/35
103 08
Generic Name
Brand Name
/
Appearance
/
Use
Caution
Pramipexole
0.375 mg/tab
Mirapex PR
( )
025258
/
P1/
( 1030801 )
20.2
Ciclesonide
160 mcg/dose ;
60 doses/ bot
Alvesco 160 Inhaler
( )
024786
/
( 1030805 )
524
(123)-8/35
Generic Name
Brand Name
/
Appearance
/
Use
Caution
Crizotinib
250 mg/cap
Xalkori
( )
025938
/ pfizer CRZ250
ALK
ALK
( 1030801 )
4153
Macitentan
10 mg/tab
Opsumit
( Patheon Italia )
/ 10
WHO II
IV
( 1030807 )
3784
(123)-9/35
103 08
Generic Name
Before New /
Use
Caution
Brand Name
/
Appearance
Brand Name
/
Appearance
Ceftazidime
1 g/vial
Cetazine
( )
041754
/ Sintum
( )
042091
/ Ceftazidime
( 1030807 )
72
Folic Acid
5 mg/tab
Folic Acid
( )
007543
/
124/
Folacin
( )
034670
/
( 1030809 )
2
(123)-10/35
Generic Name
Before New /
Use
Caution
Brand Name
/
Appearance
Brand Name
/
Appearance
Procaterol
25 mcg /tab
Pocathma- Mini
( )
045416
/
S T/273
Meptin-Mini
( )
043700
/
OG/22
( 1030809 )
2
Montelukast
10 mg/tab
Singulair
( )
022778
/
SINGULAIR/
MSD 117
Anxokast
( )
047813
/
AX 010
( ALLERGIC RHINITIS )
( 1030809 )
25.6
(123)-11/35
Generic Name
Before New /
Use
Caution
Brand Name
/
Appearance
Brand Name
/
Appearance
Dipyridamole
25 mg/tab
Solantin
( )
032530
/
Dipyridamole
( )
013801
/
STD 129
( 1030811 )
2
Levothyroxine
100 mcg/tab
Eltroxin
( GSK )
024708
/
GS 21C/100
Thyroid-S
( )
048191
/
/
( 1030811 )
2
(123)-12/35
Generic Name
Before New /
Use
Caution
Brand Name
/
Appearance
Brand Name
/
Appearance
Clarithromycin
500 mg/tab
Klaricid
( )
022420
/
e
Klarith
( )
046638
/
PBF436
OMEPRAZOLE
( H.
PYLORI )
( 1030812 )
25.1
Meclizine
25 mg/tab
Semper
( )
034272
/
148/
Meclizine
( )
004781
/
FY T069
( 1030812 )
0.66
(123)-13/35
Generic Name
Before New /
Use
Caution
Brand Name
/
Appearance
Brand Name
/
Appearance
Disterile Water
1000 mL/bot
Water for inj
( )
032379
/ Water for inj
( )
003133
/
( 1030813 )
33.75
Fludiazepam
0.25 mg/tab
Flupine
( )
041519
/
G 38/JCP
Erispan
( )
009391
/
017
( 1030813 )
2.86
(123)-14/35
Generic Name
Before New /
Use
Caution
Brand Name
/
Appearance
Brand Name
/
Appearance
Albumin 20%
10 g/ 50mL/bt
Plasbumin-20
( )
000777
/ Albumin
( TBSF )
000842
/
( 1030813 )
1212
Ramipril
10 mg/tab
Tritace
( )
023603
/
HMO HMO
Syntace
( )
051029
/
SY/11
( 1030813 )
10.5
(123)-15/35
Generic Name
Before New /
Use
Caution
Brand Name
/
Appearance
Brand Name
/
Appearance
Amoxicillin &
Clavulanate
Potassium
500 mg &
100 mg/ vial
Anbicyn
( )
042697
/ Augmentin
( )
018304
/
( 1030814 )
56
Prednisolone
5 mg/tab
Donison
( )
002531
/
CCP C03
Compesolon
( )
031676
/
PLt
(1030814 )
2
(123)-16/35
Generic Name
Before New /
Use
Caution
Brand Name
/
Appearance
Brand Name
/
Appearance
Allopurinol
100 mg/tab
Allopurinol
( )
014228
/
YUNG SHIN
Urinol
( )
020894
/
( 1030814 )
2
Lubricant K-Y Jelly
( )
000852
/
82 gm/tube
Water Gel
( )
001229
/
82 mL/tube
( 1030815 )
144
(123)-17/35
Generic Name
Before New /
Use
Caution
Brand Name
/
Appearance
Brand Name
/
Appearance
Cefepime
Maxipime
( )
021777
/
500 mg/vial
Cefim
( )
048834
/
1000 mg/vial
Cefepime
:
Maxipime
500 mg/vial,
Cefim 1000
mg/vial
(1030815 )
432
Fexofenadine
60 mg/tab
Fexofenadine
( )
057127
/
CC P/138
Allegra
()
023016
/
06
(1030814 )
3.33
(123)-18/35
Generic Name
Before New /
Use
Caution
Brand Name
/
Appearance
Brand Name
/
Appearance
Mirtazapine
30 mg/tab
Remeron
( )
024009
/
TZ 2
Mirtapine
( )
049656
/
PLT33/MTZ
( 1030815 )
23.5
Pyridostigmine
60 mg/tab
Mestinon
( )
036008
/
Antilon
( )
048908
/
PR/
( 1030815 )
3
(123)-19/35
Generic Name
Before New /
Use
Caution
Brand Name
/
Appearance
Brand Name
/
Appearance
Cimetidine
300 mg/tab
Defense
( )
22836
/
C
Stogamet
( )
038419
/
SPC/S86
( 1030816 )
2
Nicorandil
5 mg/tab
Sigmart
( )
020991
/
C-21F 5
Nirandil
( )
048991
/
ST/1001
( 1030818 )
4.82
(123)-20/35
Generic Name
Before New /
Use
Caution
Brand Name
/
Appearance
Brand Name
/
Appearance
Cephradine
1 g/vial
S-60
( )
033149
/ Lofadine
( )
029504
/
( 1030818 )
28.4
Tramadol &
Acetaminophen
37.5 mg &
325 mg/tab
Ultracet
( )
023917
/
JANSSEN/T/A
Tramacet
( )
057779
/
UC75
( 1030818 )
7.4
(123)-21/35
Generic Name
Before New /
Use
Caution
Brand Name
/
Appearance
Brand Name
/
Appearance
Hydrocortisone Na
Succinate
100 mg/ vial
Hydrocortisone
( )
057749
/ Solu-Cortef
( )
018167
/
( 1030818 )
35.3
Trihexyphenidyl
2 mg/tab
Benzox
( )
038846
/
L
Switane
( )
039597
/
SWISS 2
( 1030818 )
1.5
(123)-22/35
Generic Name
Before New /
Use
Caution
Brand Name
/
Appearance
Brand Name
/
Appearance
Aceclofenac
100 mg/tab
Tonec
( )
046613
/
UC 25
Ascofen
( )
057798
/
STD/777
( 1030818 )
6
Diltiazem
30 mg / tab
Diltisser
( )
033224
/
CCP
Cartil
( )
036966
/
SYG30
( 1030819 )
2
(123)-23/35
Generic Name
Before New /
Use
Caution
Brand Name
/
Appearance
Brand Name
/
Appearance
Cetirizine
10 mg/tab
Cety
( )
044710
/
YSP38
Cemine
( )
043403
/
SC/C18
( 1030819 )
2
Mephenoxalone
200 mg/tab
Doflex
( )
042919
/
GP/277
Mefno
( )
043257
/
OB 02
( 1030819 )
2
(123)-24/35
Generic Name
Before New /
Use
Caution
Brand Name
/
Appearance
Brand Name
/
Appearance
Sodium Chloride
0.9%500 mL/bot
Saline
( )
029836
/ Sodium Chloride
( )
009997
/ ( 1030819 )
25
Azathioprine
50 mg/tab
Azathioprine
( )
022229
/
AZP 50
Azamun
( )
025754
/
AZA50
( 1030820 )
18
(123)-25/35
Generic Name
Before New /
Use
Caution
Brand Name
/
Appearance
Brand Name
/
Appearance
Rocuronium
50 mg/5 mL/vial
Esmeron
( )
022140
/ Rocurin
( )
052611
/
( 1030820 )
307.5
Metformin
500 mg/tab
Loditon
( )
043706
/
STD/L 09
Uformin
( )
036349
/
MF1
( 1030820 )
2
(123)-26/35
Generic Name
Before New /
Use
Caution
Brand Name
/
Appearance
Brand Name
/
Appearance
Phenytoin
100 mg
Dilantin
( )
00817
/
/
PARKE/PD100
Aleviatin
( )
002320
/
Ptsh/
( 1030820 )
2
Atorvastatin
40 mg/tab
Lipitor
( )
022889
/
PD 157/40
Atorva
( )
055268
/
STD/290
( 1030820 )
35
(123)-27/35
Generic Name
Before New /
Use
Caution
Brand Name
/
Appearance
Brand Name
/
Appearance
Zoledronic Acid
4 mg/vial
Zometa
( )
023733
/ Zobonic
( )
055020
/
( HCM )
( 1030820 )
10928
(123)-28/35
Generic Name
Before New /
Use
Caution
Brand Name
/
Appearance
Brand Name
/
Appearance
Enalapril
20 mg/tab
Sintec
( )
039414
/
ST/
Enalatec
( )
039401
/
CCP/
( 1030820 )
2
Dextromethor-
phan HBr
60 mg/S.R.tab
Detosiv
( )
044781
/
LO/06
Regrow
( )
042687
/
( 1030821 )
2.8
(123)-29/35
Generic Name
Before New /
Use
Caution
Brand Name
/
Appearance
Brand Name
/
Appearance
Pilocarpine
2% 15 mL/bot
Pilocarpine
( )
032283
/
Isopto Carpine
( )
016483
/
( 1030821 )
83
Fenofibrate
160 mg/tab
Lipanthyl
( )
023770
/
160/
Fenolip-U
( )
047228
/
CH/60
( TYPE IIaIIbIIIIVV )
( 1030822 )
7.4
(123)-30/35
Generic Name
Before New /
Use
Caution
Brand Name
/
Appearance
Brand Name
/
Appearance
Polycresolsulf-
onate & Cinchocaine
100 mg &
2.5 mg/ Supp.
Ebodyl
( )
047550
/ Posuline
( )
047029
/
( 1030822 )
9.4
Calcium Gluconate Glucal Black
( )
005603
/
20%
5 mL/amp [Ca
=0.898
mEq/mL]
Calglon
( )
058006
/
10%
10 mL/amp
[Ca = 0.465
mEq/mL]
Calglon
Glucal Black
( 1030822 )
12.5
(123)-31/35
Generic Name
Before New /
Use
Caution
Brand Name
/
Appearance
Brand Name
/
Appearance
Sevoflurane
250 mL/bt
Sevoflurane
( BAXTER )
024308
/ Ultane
( Aesica )
022836
/
Sevoflurane
( 1030822 )
3516
.
(123)-32/35
Generic Name
Before New /
Use
Caution
Brand Name
/
Appearance
Brand Name
/
Appearance
Ampicillin &
Sulbactam
1.5 g/vial
Subacillin
( )
046544
/
Sulampi
( )
052553
/
( Bacteroides,
Fusobacterium,
Clostridium difficile )
Branhamella catarrhalis
(1030822 )
108
(123)-33/35
103 08
Generic Name
Brand Name
/
Appearance
/
Use
Caution
Pramipexole
0.25 mg/tab
Mirapex
( )
023280
/
P7 P7/
( PRIMARY RESTLESS LEGS
SYNDROME )
:
Mirapex PR
0.375 mg/tab ( Pramipexole)
Mirapex
0.25mg/tab ( Pramipexole )
( 1030801 )
12.8
Fluticasone 250mcg/dose ;
60 doses/bot
Flixotide Accuhaler
( )
021921
/ :
Alvesco inhaler
160mcg/dose 60doses
( Ciclesonide )
Flixotid Accuhaler
250ug/dose 60dose/bt
( Fluticasone )
( 1030805 )
516
(123)-34/35
Generic Name
Brand Name
/
Appearance
/
Use
Caution
Ornithine Aspartate
250 mg/cap
Hepacure
( )
015826
/
( 1030809 )
720
Haloperidol
mg/drop
30 mg/15 mL/bot
Haldomin
( )
030383
/
: Paliperidone
( Invega sustenna 100mg/vial
& 150mg/vial )
Haldomin
( 1030809 )
:
1. Haloperidol ( Binin-U ) 5
mg/tab
2. Haloperidol ( Binin-U ) 5
mg/mL/amp
45.5
(123)-35/35
Generic Name
Brand Name
/
Appearance
/
Use
Caution
Hyaluronic acid
16 mg/2 mL/syringe
Synvisc
( )
010770
/
ACETAMINOPHEN
( 1030819 )
:
Hyaluronic acid ( ArtiAid )
25 mg/2.5 mL/amp
Hyaluronic acid ( Hya-Joint )
25 mg/2.5 mL/amp
6600