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Dissertation Topics Covered in the Molecular and Cellular Basics of Cancer

and Development of Target-Specific Therapeutics- Cancer/Oncology

Dr. Nancy Agens, Head,

Technical Operations, Pubrica

sales@pubrica.com

In Brief

Researching cancer and its therapeutics is

an important tool for cancer studies and

medical writing services. The important

topics to be covered while writing a thesis

for cancer and its therapeutics are

discussed in scientific medical writing.

Pubrica is here to help with the easy

scientific medical writing about cancer

research and its therapeutics.

Keywords: Medical writing services,

Scientific Medical writing, services,

Scientific Medical writing companies,

medical writing solutions, regulatory

medical writing, scientific medical writing,

medical writing help, plagiarism

correction,

I. INTRODUCTION

Cancer is one of the life-threatening

diseases, responsible for the mortality rate of

0.13% of the world's population. It is

essential to perform research in the field of

cancer to overcome the emergency demand

to control the death rate of cancer. The

cancer research mainly has done to analyze

the risk, to know the type of cancer, to study

about the therapeutics etc with the help of

medical writing solutions. The first and

foremost essential knowledge to perform

cancer research for a scientist is to know

about the cellular basics of cancer

development. Once after attaining

knowledge, the researcher should submit a

thesis about his work. Here are a few

molecular and cellular basics about

cancer/oncology.

II. TOPICS COVERED IN MOLECULAR

BASICS OF CANCER

Stability of a cell

Instable gene

Oncogenesis

Suppressor genes for tumour

The growth phase of tumour

Angiogenesis

Metastasis and model systems

Therapeutics

Stability of a cell

The most common cause of cancer is an

undefined mass of cell growth. It is essential

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to check the stability of a DNA inside the

cell during the replication, transcription and

translation. Also, the DNA polymerase

enzyme is the reason for the correct

nucleotide activity. The above-mentioned

are the basics of cell functioning. Whenever

there is a problem in cell functioning, it may

lead to cell damage.

Instable gene

The cell damage can lead to genetic

instability. This process will change the

structure of DNA and causes mutations and

cancer. It will lead to the carcinogens to

easily rupture the cellular metabolic process.

This unstable gene leads to oncogenesis.

Oncogenesis

Oncogenesis is the process of transformation

of normal cells to cancer cells.

Activation of oncogene

Cell division takes place in an

unmanageable manner

Tumour suppressor genes

The tumour suppressor genes stop

functioning with inactivation of two alleles

during oncogenesis. It will mislead the cell

signalling pathways. For a non-cancerous

cell, a TSG inhibit the growth of cancer.

Hence it is called as the caretakers of the

body.

The growth phase of tumour

The forementioned oncogene and TSG

function will lead to decisive variations in

cellular growth. This tumour cells will

develop into cancer cells by shifting the

equilibrium between apoptosis and

proliferation of excessive cell growth. There

will be a disturbance in the cell cycle

pathways during this growth phase.

Angiogenesis

The tumour cells need oxygen and nutrients

supply from the blood. It will be obtained by

passing the chemical signals to the blood

vessels. However, there are several anti-

angiogenesis drugs to inhibit this process.

Metastasis and model systems

Metastasis is the process, where cancer cells

explore into foreign sites, leaving their

prime site. In the next stage of metastasis,

the cancer cells enter into the lymphatic

organs and bloodstream, that leads to cancer

death.

There are certain model systems to study the

characterization of a phenotype and

genotype. All the models should explain

using medical writing help.

Therapeutics

The need for cancer studies is mainly to

access treatment. Scientists have developed

many therapeutic agents for cancer studies

but it is still in vain to cure a certain type of

cancer especially blood cancer. The cancer

treatment will have both the advantages and

disadvantages depending upon the body

condition of a patient. There is no particular

treatment available for cancer. Out of all

chemotherapy and drug treatment is the

most common therapeutics for cancer

treatment. Drug treatment is less toxic

comparatively.

The above-mentioned passages are the

topics to be discussed while doing a

dissertation in cancer studies. It will ample

information about the entry of cancer cells

and the phases of cancer at a molecular level

in our body. Medical writing solutions are

there to complete the dissertation of topics

of basic cellular level of cancer.

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III. CONCLUSION

Pubrica has given the details for the basic

level cancer study research works. It will be

helpful for the researchers to develop a

vaccine or medicine that inhibits cancer. The

cancer study dissertation can be done with

the help of medical writing solutions and

services.These basics will also help to do

evaluations in future cancer studies. This

article is fully checked with plagiarism

correction and will be analysed by scientific

writing companies.

REFERENCES

1. Knisely, A., Wu, J., Kaplan, S. J., Zhou, Z. N.,

Melamed, A., Tergas, A. I., ... &Hershman, D. L.

(2020). Coronavirus Spectrum Infections (COVID-19,

MERS, SARS) in Cancer Patients: A Systematic

Review of the Literature. Cancer Investigation, (just-

accepted), 1-23.

2. Wang, L. H., Wu, C. F., Rajasekaran, N., & Shin, Y.

K. (2018). Loss of tumour suppressor gene function in

human cancer: An overview. Cellular Physiology and

Biochemistry, 51(6), 2647-2693.

3. Yin, H., Qu, J., Peng, Q., &Gan, R. (2019). Molecular

mechanisms of EBV-driven cell cycle progression and

oncogenesis. Medical microbiology and

immunology, 208(5), 573-583.

4. Zearmal, S., & Allen, K. (2019). 117 Qualitative

study: exploring the views of cancer researchers

surrounding Brexit and its impact on their work.