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THE CYCLE CELL AND STRUCTURE DNA Laura Elena Cuartas Molecular Biology July 22/2012 UPB- Medellín

Biologia molecular Laura Cuartas Q

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Page 1: Biologia molecular Laura Cuartas Q

THE CYCLE CELL AND STRUCTURE DNA

Laura Elena CuartasMolecular BiologyJuly 22/2012UPB- Medellín

Page 2: Biologia molecular Laura Cuartas Q

FOLDING

Page 3: Biologia molecular Laura Cuartas Q

FOLDING

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Telomeres and telomerase serve to give information about age and pathologies like cancer.

Cell division is a important process to give rise to new

cells containing their complete genomas.

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Using biochemical and genetic assays the protein Lem4 is structurally different in human cells and embryos of the worm, but have the same function in cell division.

IDENTIFIED A ESSENTIAL PROTEIN IN NUCLEAR ENVELOPE ASSEMBLY IN CELL

DIVISION, ACCORDING TO THE UPO

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Lem4 is a protein which simultaneously co-ordinates the activity of kinases and phosphatases on a target protein essential for cell division.

IDENTIFIED A ESSENTIAL PROTEIN IN NUCLEAR ENVELOPE ASSEMBLY IN CELL

DIVISION, ACCORDING TO THE UPO

Page 8: Biologia molecular Laura Cuartas Q

It is essential that the nuclear envelope disappears during cell division and then reassemble it correctly, to occur this is necessary for the participation of kinases and phosphatases proteins.

IDENTIFIED A ESSENTIAL PROTEIN IN NUCLEAR ENVELOPE ASSEMBLY IN CELL

DIVISION, ACCORDING TO THE UPO

Page 9: Biologia molecular Laura Cuartas Q

Lem4 protein has a relation with the cancer patients

IDENTIFIED A ESSENTIAL PROTEIN IN NUCLEAR ENVELOPE ASSEMBLY IN CELL

DIVISION, ACCORDING TO THE UPO

Page 10: Biologia molecular Laura Cuartas Q

OBSERVATION

In this study we can observe the importance of phosphorylation and desphosphorylation reactions and its essential role in cell division and cell operation.

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Telomerases protect chromosomes from deteriorating and guard the genetic information at the ends of chromosomes during cell division. Besides’ they are considered markers of biological or cellular aging.

ANXIETY LINKED TO SHORTENED TELOMERES

ACCELERATED AGING: RESEARCH

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Shortened telomeres have been linked to increased risk of cancers, heart disease, dementia and mortality.

ANXIETY LINKED TO SHORTENED TELOMERES

ACCELERATED AGING: RESEARCH

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The length of telomeres depends on the stress, worries and phobias.

ANXIETY LINKED TO SHORTENED TELOMERES

ACCELERATED AGING: RESEARCH

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OBSERVATION

I think anxienty and stress are emotional feeling that people can control, because these affect cromosomes in the telomeres and reduce life average.

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MEDICAL UTILITY

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The DNA structure is very important because it has the information about each personal genome, this study has to protect the life and the personal safety and the culture of the people because al cientific investigation has to be ethics.

MEDICAL UTILITY

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Knowledge of the nuclear envelope met know different molecules involved in cell cycle and that way related pathologies such as cancer.

MEDICAL UTILITY

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• MARTINEZ SANCHÉZ. LINA MARÍA. BIOLOGÍA MOLECULAR. 7. ED. MEDELLÍN: UPB. FAC. DE MEDICINA, 2012. 44-51 PAG.

• Asencio C. Identified a essential protein in nuclear envelope assembly in cell division, according to the UPO.Europapresst [Internet journal] 2012 Jul [access 20 of July of 2012]. Available: http://www.europapress.es/andalucia/sevilla-00357/noticia-identifican-proteina-esencial-ensamblaje-envoltura-nuclear-division-celular-upo-20120713150648.html

• Okereke O. Anxiety linked to shortened telomeres, accelerated aging: research. Medicalxpress [Internet journal] 2012 Jul [access 20 of July of 2012]. Available: http://medicalxpress.com/news/2012-07-anxiety-linked-shortened-telomeres-aging.html

BIBLIOGRAPHY

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“Your imagination

is your preview of

life’s coming

attractions.”

Albert Eisnten