1 Ancylostomiasis 钩虫病 08 动医 2 班 Speaker ：赖华英 Partner ：余剑敏 罗宇声 利...

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Ancylostomiasis钩虫病

08 动医 2 班 Speaker ：赖华英 Partner：余剑敏 罗宇声 利 钊 覃捷梅

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AncyloslomiasisAncyloslomiasis钩虫病钩虫病

EpidemiologyEpidemiology流行病学流行病学DiagnosisDiagnosis

诊断诊断

ControlControl控制控制

ReferencesReferences参考书参考书

Life cycleLife cycle生活周期生活周期

MorphologyMorphology形态学形态学

IntroductionIntroduction引言引言

LesionsLesions病变病变

SSymptomsymptoms症状症状

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1 Introduction

钩口科（ Ancylostomatidae）1,Ancylostoma caninum犬钩口线虫2,Unciaria stenocephala狭头弯口线虫3, Ancylostomiasis braziliense巴西钩口线虫4, Ancylostomiasis ceylanicum锡兰钩口线虫5,Necator americanus美洲板口线虫 (Human)

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2 Morphology

The oval-shaped(椭圆的 ) egg of Ancylostoma caninum65μm×37μm, obtuse（钝的） in the ends, colourless and translucent（半透明的） .

The egg of 4-cell stage

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If the sample was placed for a long time, the egg of 4-cell stage will change into 8-cells stage or mulberry-shaped(桑葚状 ).

The egg of 8-cell stage The mulberry-like egg

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Ancylostoma caninum Unciaria stenocephala

cutting plates with teeth

Buccal capsule

Copulatory bursa

Side of female tail

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Site of infection

colour male female The color/shape/size of egg

Buccalcapsuel

Ancylostoma

caninum

Small intestine

yellowish white

10~12mm

14~16mm

beige/oval-shaped/55~76um×34~45um

The main differential diagnosis is the cutting plate

Unciaria stenocephala

Small intestine

yellow

5~8.5mm

7~10mm

-/oval-shaped/65~80um×40~50 um

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3 Life cycle

Direct life cycle

Infective stage ：filariform(丝状蚴 )

Site of infection ：small intestine

Host ： dog and cat

Diagnostic stage ：egg

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Three Routes

• Transcolostral: Infected bitch nurse offspring the larvae

• Infection through ingestion:gut wall circulation liver heart lung alveoli coughed up and swallowed small intestine

• Infection through the skin:skin circulation heart lung alveoli coughed up and swallowed small intestine

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人钩虫的生活史

rhabtidiform larva

filariform larva

egg

L1

L2

L3 morula

heart

lung

In the intestine

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3 Life cycle

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4 Epidemiology

Ancylostoma caninum is one of the most common parasites in dogs and is widespread in the world.

Routes of infection: peroral infection( 经口传染 ) 、 by the skin(经皮肤 ) 、 via the placental(通过胎盘 ) or colostrum (初乳 )

This disease occurs most in summer.

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5 Signs or Symptoms

1.Acute type:

emaciation(消瘦 ) 、 pale mucosa(黏膜苍白 ) 、 decreased appetite(食欲减退 ) 、 vomiting(呕吐 ) 、 gastricism(消化障碍 ) 、 diarrhea(下痢 ) 、 constipation(便秘 ) 、 bloody stool (粪便带血 ) 、 anaemia(贫血 )

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2.Chronic type:light anaemia 、 malnutrition(营养不良 ) 、 gastrointestinal dysfunction(胃肠功能紊乱 )3.Uncinarial dermatitis(钩虫性皮炎 )

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6 Lesions

Hemorrhage(出血 ) 、 ulcer on intestinal mucosa

Dermatitis(皮炎 )

Pneumorrhagia(肺出血 ) and pneumonia(肺炎 )

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7 Diagnosis

1. Direct smear

2. Flotation method

3. Fecal culture

4. IFA

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8 Control1. The treatment of the dogs and cats

Drug of choice is dimphenol(二碘硝基酚 ).

Other effective drugs include

levamisole (左旋咪唑 ), albendazole(丙硫咪唑 ),

ivermectin(伊维菌素 ).

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2. Comprehensive prevention (1) Treating sick dogs and cats in time and avoid feeding dogs and cats with raw foods. (2) Keep the dogtery(犬舍 ) dry, feces management（粪便处理 ), Kill eggs by boiling water and solarization. (3) Deratization(灭鼠 ).

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9 References

【 1 】 韦华，杨玉荣 . 宠物犬犬钩虫的调查及生活史各期形态观察 [J] . 中国人兽共患病学报 .2006,22(8):789-791

【 2 】 李国清 .兽医寄生虫（双语版） [M]．北京：中国农业出版社， 2006,339-342

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