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2013 年業績 【原著】 1. Matsunaga K, Akamatsu K, Miyatake A, Ichinose M: Natural history and risk factors of obstructive changes over a 10-year period in severe asthma. Respir Med 107(3): 355-360, 2013 2. Matsunaga K, Kawabata H, Hirano T, Sugiura H, Minakata Y, Ichinose M: Difference in time-course of improvement in asthma control measures between budesonide and budesonide/formoterol. Pulm Pharmacol Ther 26(2): 189-194, 2013 3. Matsunaga K, Kawabata H, Hirano T, Sugiura H, Minakata Y, Ichinose M: Difference in time-course of improvement in asthma control measures between budesonide and budesonide/formoterol. World Biomedical Frontiers Allergy 2013 May(2)-5, 2013 4. Farid M, Kanaji N, Nakanishi M, Gunji Y, Michalski J, Iwasawa S, Ikari J, Wang X, Basma H, Nelson AJ, Liu X, Rennard SI: Smad3 mediates cigarette smoke extract (CSE) induction of VEGF release by human fetal lung fibroblasts. Toxicol Lett 220(2): 126-134, 2013 5. Hirano T, Matsunaga K, Sugiura H, Minakata Y, Koarai A, Akamatsu K, Ichikawa T, Furukawa K, Ichinose M: Persistent elevation of exhaled nitric oxide and modification of corticosteroid therapy in asthma. Respir Investig 51: 84-91, 2013 6. Ichikawa T, Sugiura H, Koarai A, Kikuchi T, Hiramatsu M, Kawabata H, Akamatsu K, Hirano T, Nakanishi M, Matsunaga K, Minakata Y, Ichinose M: 25-Hydroxycholesterol promotes fibroblast-mediated tissue remodeling through NF-κβ dependent pathway. Experimental Cell Research 319: 1176-1186, 2013 7. Matsunaga K, Hirano T, Akamatsu K and Minakata Y: Predictors for Identifying the Efficacy of Systemic Steroids on Sustained Exhaled Nitric Oxide Elevation in Severe Asthma. Allergol Int 62: 359-365, 2013 8. Wang X, Nelson A, Weiler ZM, Patil A, Sato T, Kanaji N, Nakanishi M, Michalski J, Farid M, Basma H, Levan TD, Miller-Larsson A, Wieslander E, Muller KC, Holz O, Magnussen H, Rabe KF, Liu X, Rennard SI: Anti-inflammatory effects of budesonide in human lung fibroblast are independent of histone deacetylase 2. J Inflamm Res 6: 109-119, 2013 9. Maeshima E, Furukawa K: A case of fibromyalgia syndrome with anaphylaxis induced by intradermal injection of purified protein derivative. - 1 -

2013 年業績 - wakayama-med-3nai.comMaeshima E, Furukawa K: A case of fibromyalgia syndrome with anaphylaxis induced by intradermal injection of purified protein derivative. - 1

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Page 1: 2013 年業績 - wakayama-med-3nai.comMaeshima E, Furukawa K: A case of fibromyalgia syndrome with anaphylaxis induced by intradermal injection of purified protein derivative. - 1

2013 年業績 【原著】

1. Matsunaga K, Akamatsu K, Miyatake A, Ichinose M: Natural history and risk factors of obstructive changes over a 10-year period in severe asthma. Respir Med 107(3): 355-360, 2013

2. Matsunaga K, Kawabata H, Hirano T, Sugiura H, Minakata Y, Ichinose M: Difference in time-course of improvement in asthma control measures between budesonide and budesonide/formoterol. Pulm Pharmacol Ther 26(2): 189-194, 2013

3. Matsunaga K, Kawabata H, Hirano T, Sugiura H, Minakata Y, Ichinose M: Difference in time-course of improvement in asthma control measures between budesonide and budesonide/formoterol. World Biomedical Frontiers Allergy 2013 May(2)-5, 2013

4. Farid M, Kanaji N, Nakanishi M, Gunji Y, Michalski J, Iwasawa S, Ikari J, Wang X, Basma H, Nelson AJ, Liu X, Rennard SI: Smad3 mediates cigarette smoke extract (CSE) induction of VEGF release by human fetal lung fibroblasts. Toxicol Lett 220(2): 126-134, 2013

5. Hirano T, Matsunaga K, Sugiura H, Minakata Y, Koarai A, Akamatsu K, Ichikawa T, Furukawa K, Ichinose M: Persistent elevation of exhaled nitric oxide and modification of corticosteroid therapy in asthma. Respir Investig 51: 84-91, 2013

6. Ichikawa T, Sugiura H, Koarai A, Kikuchi T, Hiramatsu M, Kawabata H, Akamatsu K, Hirano T, Nakanishi M, Matsunaga K, Minakata Y, Ichinose M: 25-Hydroxycholesterol promotes fibroblast-mediated tissue remodeling through NF-κβ dependent pathway. Experimental Cell Research 319: 1176-1186, 2013

7. Matsunaga K, Hirano T, Akamatsu K and Minakata Y: Predictors for Identifying the Efficacy of Systemic Steroids on Sustained Exhaled Nitric Oxide Elevation in Severe Asthma. Allergol Int 62: 359-365, 2013

8. Wang X, Nelson A, Weiler ZM, Patil A, Sato T, Kanaji N, Nakanishi M, Michalski J, Farid M, Basma H, Levan TD, Miller-Larsson A, Wieslander E, Muller KC, Holz O, Magnussen H, Rabe KF, Liu X, Rennard SI: Anti-inflammatory effects of budesonide in human lung fibroblast are independent of histone deacetylase 2. J Inflamm Res 6: 109-119, 2013

9. Maeshima E, Furukawa K: A case of fibromyalgia syndrome with anaphylaxis induced by intradermal injection of purified protein derivative.

- 1 -

Page 2: 2013 年業績 - wakayama-med-3nai.comMaeshima E, Furukawa K: A case of fibromyalgia syndrome with anaphylaxis induced by intradermal injection of purified protein derivative. - 1

Mod Rheumatol 23(3): 593-596, 2013 10. Hirano T, Matsunaga K, Sugiura H, Minakata Y, Koarai A, Akamatsu K,

Ichikawa T, Furukawa K, Ichinose M: Relationship between alveolar nitric oxide concentration in exhaled air and small airway function in COPD. J Breath Res 7(4): 046002, 2013

11. Akamatsu H, Inoue A, Mitsudomo T, Kobayashi K, Nakagawa K, Mori K, Nukiwa T, Nakanishi Y, Yamamoto N: Interstitial Lung Disease Associated with Gefitinib in Japanese Patients with EGFR-mutated Non-small-cell Lung Cancer: Combined Analysis of Two Phase Ⅲ Trials(NEJ 002 and WJTOG 3405). Jpn J Clin Oncol 43(6): 664-668, 2013

12. Inaba H, Hayakawa T, Miyamoto W, Takeshima K, Yamaoka H, Furukawa Y, Kawashima H, Ariyasu H, Wakasaki H, Furuta H, Nishi M, Nakao T, Sasaki H, Okada Y, Matsunaga K, Nakamura Y and Akamizu T: IgG4-related Ocular Adnexal Disease Mimicking Thyroid-associated Orbitopathy. Intern Med 52(22):2545-2551, 2013

13. Minakata Y, Morishita Y, Hiramatsu M, Ichikawa T, Akamatsu K, Hirano T, Nakanishi M, Matsunaga K and Ichinose M: Effect of Transdermal Tulobuterol Patch on the Physical Activity in Eight Male Subjects with Chronic Obstructive Pulmonary Disease. Clin Res Pulmonol 1(2): 1010, 2013

14. Shukuya T, Takahashi T, Harada H, Ono A, Akamatsu H, Taira T, Kenmotsu H, Naito T, Murakami H, Endo M, Takahashi K, Yamamoto N: Chemoradiotherapy for limited-disease small-cell lung cancer in elderly patients aged 75 years or older. Jpn J Clin Oncol 43(2): 176-183, 2013

15. Tokito T, Shukuya T, Akamatsu H, Taira T, Ono A, Kenmotsu H, Naito T, Murakami H, Takahashi T, Endo M, Yamamoto N: Efficacy of bevacizumab-containing chemotherapy for non-squamous non-small cell lung cancer with bone metastases. Cancer Chemother Pharmacol 71(6): 1493-1498, 2013

16. Kanaji N, Nelson A, Wang X, Sato T, Nakanishi M, Gunji Y, Basma H, Michalski J, Farid M, Rennard SI, Lui X: Differential roles of JNK, ERK1/2, and p38 mitogen-activated protein kinases on endothelial cell tissue repair functions in response to tumor necrosis factor-α. J Vasc Res 50(2): 145-156, 2013

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Akamatsu H, Watanabe R, Ono S, Mori K, Kanbara H, Yamaguchi K, Tanaka T, Matsunaga T, Yamamoto N: Size-based isolation of circulating tumor cells in lung cancer patients using a microcavity array system. PLoS One 8(6): e67466, 2013

18. Ono A, Takahashi T, Oishi T, Sugino T, Akamatsu H, Shukuya T, Taira T, Kenmotsu H, Naito T, Murakami H, Nakajima T, Endo M, Yamamoto N: Acute lung injury with alveolar hemorrhage as adverse drug reaction related to crizotinib. J Clin Oncol 31(26): e417-419, 2013

19. Ono A, Takahashi T, Mori K, Akamatsu H, Shukuya T, Taira T, Kenmotsu H, Naito T, Murakami H, Nakajima T, Endo M, Yamamoto N: Prognostic impact of serum CYFRA 21-1 in patients with advanced lung adenocarcinoma: a retrospective study. BMC Cancer 13: 354, 2013

20. Imai H, Shukuya T, Takahashi T, Fujiwara S, Mori K, Ono A, Akamatsu H, Taira T, Kenmotsu H, Naito T, Kaira K, Murakami H, Harada H, Endo M, Nakajima T, Yamamoto N: Comparison of the time-to-response between radiotherapy and epidermal growth factor receptor--tyrosine kinase inhibitors for advanced non-small cell lung cancer with EGFR mutation. Anticancer Res 33(8): 3279-3284, 2013

21. Maeshima E, Furukawa K, Maeshima S, Koshiba H, Sakamoto W: Hyposalivation in autoimmune diseases. Rheumatol Int 33(12): 3079-3082, 2013

22. Watanabe R, Ito I, Kenmotsu H, Endo M, Yamamoto N, Ohde Y, Kondo H, Nakajima T, Kameya T: Large Cell Neuroendocrine Carcinoma of the Lung: Is it Possible to Diagnose from Biopsy Specimens? Jpn J Clin Oncol 43(3): 294-304, 2013

23. Serizawa M, Takahashi T, Yamamoto N, Koh Y: Combined treatment with erlotinib and a transforming growth factor-β type I receptor inhibitor effectively suppresses the enhanced motility of erlotinib-resistant non–small-cell lung cancer cells. J Thorac Oncol 8(3): 259-269, 2013

24. Kiyota H, Okamoto I, Takeda M, Daga H, Naito T, Miyazaki M, Okada H, Hayashi H, Tanaka K, Terashima M, Azuma K, Murakami H, Takeda K, Yamamoto N, Nakagawa K: Phase I and pharmacokinetic study of gefitinib and S-1 combination therapy for Advanced Adenocarcinoma of the Lung. Cancer Chemother Pharmacol 71(4): 859-865, 2013

25. Yoshioka H, Okamoto I, Morita S, Ando M, Takeda K, Seto T, Yamamoto N, Saka H, Atagi S, Hirashima T, Kudoh S, Satouchi M, Ikeda N, Iwamoto Y,

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Sawa T, Nakanishi Y, Nakagawa K.: Efficacy and safety analysis according to histology for S-1 in combination with carboplatin as first-line chemotherapy in patients with advanced non-small-cell lung cancer: updated results of the West Japan Oncology Group LETS study. Ann Oncol 24(5): 1326-1331, 2013

26. Yamamoto N, Murakami H, Nishina T, Hirashima T, Sugio K, Muro K, Takahashi T, Naito T, Yasui H, Akinaga S, Koh Y, Boku N: The effect of CYP2C19 polymorphism on the safety, tolerability, and pharmacokinetics of tivantinib (ARQ 197): Results from a phase I trial in advanced solid tumors. Ann Oncol 24(6): 1653-1659, 2013

27. Okamoto I, Aoe K, Kato T, Hosomi Y, Yokoyama A , Imamura F, Kiura K, Hirashima T, Nishio M, Nogami N, Okamoto H, Saka H, Yamamoto N, Yoshizuka N, Sekiguchi R, Kiyosawa K, Nakagawa K, Tamura T: Pemetrexed and carboplatin followed by pemetrexed maintenance therapy in chemo-naïve patients with advanced nonsquamous non-small-cell lung cancer. Invest New Drugs 31(5): 1275-1282, 2013

28. Satouchi M, Okamoto I, Sakai H, Yamamoto N, Ichinose Y, Ohmatsu H, Nogami N, Takeda K, Mitsudomi T, Kasahara K, Negoro S: Efficacy and safety of weekly nab-paclitaxel plus carboplatin in patients with advanced non-small cell lung cancer. Lung Cancer 81(1): 97-101, 2013

29. Harada H, Nishio M, Murakami H, Ohyanagi F, Kozuka T, Ishikura S, Naito T, Kaira K, Takahashi T, Horiike A, Nishimura T, Yamamoto N: Dose-escalation study of three-dimensional conformal thoracic radiotherapy with concurrent S-1 and cisplatin for inoperable stage III non–small-cell lung cancer. Clin Lung Cancer 14(4): 440-445, 2013

30. Kogure Y, Ando M, Saka H, Chiba Y, Yamamoto N, Asami K, Hirashima T, Seto T, Nagase S, Otsuka K, Yanagihara K, Takeda K, Okamoto I, Aoki T, Takayama K, Yamasaki M, Kudoh S, Katakami N, Miyazaki M, Nakagawa K: Histology and Smoking Status Predict Survival of Patients with Advanced Non-Small-Cell Lung Cancer: Results of West Japan Oncology Group (WJOG) Study 3906L. J Thorac Oncol 8(6):753-758, 2013

31. Hosokawa M, Yoshikawa T, Negishi R, Yoshino T, Koh Y, Kenmotsu H, Naito T, Takahashi T, Yamamoto N, Kikuhara Y, Kanbara H, Tanaka T, Yamaguchi K, Matsunaga T: Microcavity Array System for Size-Based Enrichment of Circulating Tumor Cells from the Blood of Patients with Small-Cell Lung Cancer. Anal Chem 85(12): 5692-5698, 2013

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32. Niwakawa M, Yamaguchi R, Onozawa Y, Yasui H, Taku K, Naito T, Akinaga S, Boku N, Yamamoto N : Phase I study of highly selective inhibitor of VEGFR tyrosine kinase, tivozanib, in Japanese patients with solid tumors. Cancer Sci 104(8): 1039-1044, 2013

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34. Seto T, Kiura K, Nishio M, Nakagawa K, Maemondo M, Inoue A, Hida T, Yamamoto N, Yoshioka H, Harada M, Ohe Y, Nogami N, Takeuchi K, Shimada T, Tanaka T, Tamura T: CH5424802 (RO5424802) for patients with ALK-rearranged advanced non-small-cell lung cancer (AF-001JP study): a single-arm, open-label, phase 1–2 study. Lancet Oncol 14(7): 590-598 2013

35. Sequist LV, Yang JC, Yamamoto N, O’Byrne K, Hirsh V, Mok T, Geater SL, Orlov S, Tsai CM, Boyer M, Su WC, Bennouna J, Kato T, Gorbunova V, Lee KH, Shah R, Massey D, Zazulina V, Shahidi M, Schuler M: Phase III study of aftinib or cisplatin plus pemetrexed in metastatic lung adenocarcinoma patients with epidermal growth factor receptor mutations. J Clin Oncol 31(27): 3327-3334, 2013

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50. 南方良章, 早乙女徹, 橋本賢一, 一ノ瀬正和: 日本人の COPD 患者における

フルチカゾンフランカルボン酸エステル/ビランテロール配合剤(FF/VI)の長

期投与試験. 呼吸 32(10): 956-967, 2013

【学会報告】

国際学会

[シンポジウム] 1. K. Matsunaga. Natural History and Risk Factors of Obstructive Changes

in Severe Asthma. The 23rd Congress of Interasma Japan/North Asia, 2013.06.28, Tokyo, Japan

[一般演題] 1. Y. Honda, Y. Minakata, Y. Morisita, A. Sugino, M. Hiramatsu, T. Ichikawa,

K. Akamatsu, T. Hirano, M. Nakanishi, K. Matsunaga. Possibility of flying disc game for maintenance of physical activity in patients with long term oxygen therapy. 2013 ATS International Conference, 2013.05.17-2013.05.22, Philadelphia, Pennsylvania, USA

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Page 8: 2013 年業績 - wakayama-med-3nai.comMaeshima E, Furukawa K: A case of fibromyalgia syndrome with anaphylaxis induced by intradermal injection of purified protein derivative. - 1

2. K. Matsunaga, T. Hirano, M. Ichinose. Difference In Time-Course Of Improvement In Asthma Control Measures Between Budesonide And Budesonide/Formoterol. 2013 ATS International Conference, 2013.05.17-2013.05.22, Philadelphia, Pennsylvania, USA

3. F. Ohyanagi, N. Yamamoto, A. Horiike, T. Horai, T. Kozuka, H. Murakami, H. Harada, T. Takahashi, Y. Nakamura, M. Nishio. Long-term results of a phase II trial of S-1 and cisplatin with concurrent thoracic radiotherapy for locally advanced non-small cell lung cancer. 49th American Society of Clinical Oncology Meeting, 2013.05.31-2013.06.04, Chicago, Illinois, USA

4. H. Kenmotsu, M. Serizawa, Y. Koh, M. Isaka, T. Takahashi, H. Murakami, T. Naito, T. Taira, T. Shukuya, A. Ono, H. Akamatsu, H. Imai, K. Mori, M. Endo, T. Nakajima, Y. Ohde, N. Yamamoto. Concordance between formalin-fixed paraffin-embedded biopsy samples and surgically resected snap-frozen samples in multiplexed molecular profiling of lung cancers. 49th American Society of Clinical Oncology Meeting, 2013.05.31-2013.06.04, Chicago, Illinois, USA

5. Y. Koh, H. Kenmotsu, M. Serizawa, M. Isaka, K. Mori, H. Imai, H. Akamatsu, A. Ono, T. Naito, T. Taira, H. Murakami, T. Takahashi, M. Endo, T. Nakajima, Y. Ohde, N. Yamamoto. Identification of actionable mutations in surgically resected tumor specimens from Japanese patients with non-small cell lung cancer by ultra-deep targeted sequencing. 2013 Annual Meeting Abstract, 49th American Society of Clinical Oncology Meeting, 2013.05.31-2013.06.04, Chicago, Illinois, USA

6. T. Shukuya, M. Serizawa, M. Abe, H. Akamatsu, T. Tokito, H. Imai, A. Ono, T. Taira, H. Kenmotsu, T. Naito, H. Murakami, T. Takahashi, M. Endo, T. Nakajima, Y. Koh, N. Yamamoto. Multiplexed genetic analysis of malignant pleural mesothelioma and the relationship to clinical outcome. 2013 Annual Meeting Abstract, 49th American Society of Clinical Oncology Meeting, 2013.05.31-2013.06.04, Chicago, Illinois, USA

7. K. Wakuda, H. Kenmotsu, M. Serizawa, Y. Koh, M. Isaka, T. Takahashi, H. Murakami, T. Naito, T. Taira, T. Shukuya, A. Ono, H. Akamatsu, H. Imai, K. Mori, M. Endo, T. Nakajima, Y. Ohde, N. Yamamoto. Molecular profiling of small cell lung cancers in Japanese patients. 49th Annual Meeting Abstract, 2013 American Society of Clinical Oncology Meeting, 2013.05.31-2013.06.04, Chicago, Illinois, USA

8. T. Oyakawa, T. Takahashi, H. Imai, H. Akamatsu, A. Ono, T. Taira, H. Kenmotsu,

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Page 9: 2013 年業績 - wakayama-med-3nai.comMaeshima E, Furukawa K: A case of fibromyalgia syndrome with anaphylaxis induced by intradermal injection of purified protein derivative. - 1

T. Naito, H. Murakami, M. Endo, N. Yamamoto. CT image characteristics of anaplastic lymphoma kinase fusion gene positive (ALK-P) advanced stage non-small cell lung cancer (NSCLC). 49th American Society of Clinical Oncology Meeting, 2013.05.31-2013.06.04, Chicago, Illinois, USA

9. H. Imai, M. Serizawa, T. Takahashi, K. Mori, A. Ono, H. Akamatsu, T. Taira, Y. Nakamura, H. Kenmotsu, T. Naito, H. Murakami, Y. Koh, M. Endo, T. Nakajima, N. Yamamoto. Pharmacogenetic study of Japanese patients with advanced nonsquamous non-small cell lung cancer treated with pemetrexed plus cisplatin. 49th American Society of Clinical Oncology Meeting, 2013.05.31-2013.06.04, Chicago, Illinois, USA

10. T. Mitsudomi, Y. Iwamoto, K. Nishio, T. Yamanaka, H. Yoshioka, H. Tada, M. Yoshimura, I. Yoshino, I. Okamoto, S. Sugawara, S. Kudoh, N. Yamamoto, M. Ohta, Y. Ichinose, S. Atagi, M. Okada, H. Saka, N. Katakami, K. Nakagawa, Y. Nakanishi. Biomarker analysis of WJOG4107, a randomized phase II trial of adjuvant chemotherapy with S-1 versus CDDP+S-1 for resected stage II-IIIA non-small cell lung cancer (NSCLC). 49th American Society of Clinical Oncology Meeting, 2013.05.31-2013.06.04, Chicago, Illinois, USA

11. K. Nakagawa, K. Kiura, M. Nishio, T. Seto, M. Maemondo, A. Inoue, T. Hida, N. Yamamoto, H. Yoshioka, M. Harada, Y. Ohe, N. Nogami, K. Takeuchi, T. Shimada, T. Tanaka, T. Tamura. A phase I/II study with a highly selective ALK inhibitor CH5424802 in ALK-positive non-small cell lung cancer (NSCLC) patients: Updated safety and efficacy results from AF-001JP. 49th American Society of Clinical Oncology Meeting, 2013.05.31-2013.06.04, Chicago, Illinois, USA

12. BJ. Solomon, SN. Gettinger, GJ. Riely, SM. Gadgeel, H. Nokihara, JY. Han, T. Hida, M. Satouchi, E. Baldini, S. Siena, N. Yamamoto, L. Horn, VR. Tassell, A. Polli, DR. Camidge. Subgroup analysis of crizotinib versus either pemetrexed (PEM) or docetaxel (DOC) in the phase III study (PROFILE 1007) of advanced ALK-positive non-small cell lung cancer (NSCLC). 49th American Society of Clinical Oncology Meeting, 2013.05.31-2013.06.04, Chicago, Illinois, USA

13. H. Hashimoto, T. Yamanaka, Y. Shimada, K. Arata, R. Matsui, K. Goto, T. Takiguchi, F. Ohyanagi, Y. Kogure, N. Nogami, M. Nakao, K. Takeda, K. Azuma, S. Nagase, T. Hayashi, K. Fujiwara, T. Shimada, N. Seki, K. Suzuki, N. Yamamoto. Palonosetron (PALO) versus granisetron (GRA) in the triplet regimen with dexamethasone (DEX) and aprepitant (APR) for preventing

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chemotherapy-induced nausea and vomiting (CINV) in patients (pts) receiving highly emetogenic chemotherapy (HEC) with cisplatin (CDDP): A randomized, double-blind, phase III trial. 49th American Society of Clinical Oncology Meeting, 2013.05.31-2013.06.04, Chicago, Illinois, USA

14. T. Hirano. Predictors for identifying the efficacy of systemic steroids on sustained exhaled nitric oxide elevation in severe asthma. The 23rd Congress of Interasma Japan/North Asia, 2013.06.28, Tokyo, Japan

15. K. Matsunaga, A. Oka, T. Kamei, Y. Sakamoto, Y. Minakata. Ongoing allergic rhinitis impairs asthma control by enhancing the lower airway inflammation. 2013 ERS Annual Congress, 2013.09.07-2013.09.11, Barcelona, Spain

16. T. Ichikawa, H. Sugiura, A. Koarai, T. Kikuchi, M. Ichinose. Activation of TLR3 augments the production of MMPs in human lung fibroblasts via inducible NOS dependent pathway. 2013 ERS Annual Congress, 2013.09.07-2013.09.11, Barcelona, Spain

17. T. Kikuchi, H. Sugiura, T. Ichikawa, A. Koarai, M. Ichinose. Promotional effect of 27-hydroxycholesterol in the release of matrix metalloproteinases by lung fibroblasts. 2013 ERS Annual Congress, 2013.09.07-2013.09.11, Barcelona, Spain

18. K. Kanai, A. Koarai, H. Sugiura, T. Ichikawa, T. Kikuchi, K. Akamatsu, T. Hirano, M. Nakanishi, K. Matsunaga, Y. Minakata and M. Ichinose. Cigarette smoke augments MUC5AC mucin production via TLR3-EGFR pathway in airway epithelial cells. 2013 ERS Annual Congress, 2013.09.07-2013.09.11, Barcelona, Spain

19. T. Yoshino, N. Fusem T. Doi, A. Otsu, S. Fujitani, Y. Aramaki, H. Murakami, H. Yasui, N. Takahashi, N. Yamamoto. Phase I study of U3-1565, a fully human anti-HB-EGF monoclonal antibody in Japanese patients with solid tumor. 17th ECCO-38th ESMO-32th ESTRO European Cancer Congress, 2013.09.27-2013.10.01, Amsterdam, Noord-Holland, Nederland

20. K. Tamura, K. Aiba, T. Saeki, Y. Nakanishi, T. Kamura, H. Baba, K. Yoshida, N. Yamamoto, Y. Kitagawa, Y. Maehara. Prospective observational study on chemotherapy-induced nausea and vomiting (CINV) for cancer patients who were to receive moderately and highly emetogenic chemotherapy (MEC and HEC) and primary care medical staffs’perception on CINV by the CINV Study Group of Japan. 17th

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ECCO-38th ESMO-32th ESTRO European Cancer Congress, 2013.09.27-2013.10.01, Amsterdam, Noord-Holland, Nederland

21. Y. Koh, H. Kenmotsu, M. Serizawa, M. Isaka, T. Naito, T. Takahashi, M. Endo, T. Nakajima, Y. Ohde, N. Yamamoto. Highly multiplexed detection of actionable mutations in surgically resected tumor speciments from Japanese patients with lung adenocarcinoma by ultra-deep targeted sequencing. 17th ECCO-38th ESMO-32th ESTRO European Cancer Congress, 2013.09.27-2013.10.01, Amsterdam, Noord-Holland, Nederland

22. A. Inoue, N. Katakami, S. Atagi, K. Goto, T. Hida, T. Horai, Y. Seki, R. Ebisawa, M. Shahidi, N. Yamamoto. Individualized dose adjustments facilitate continuous treatment with afatinib, allowing patients (pts) with advanced NSCLC previously treated with chemotherapy and erlotinib or gefitinb to maintain clinical benefit. 17th ECCO-38th ESMO-32th ESTRO European Cancer Congress, 2013.09.27-2013.10.01, Amsterdam, Noord-Holland, Nederland

23. M. Schuler, JC. Yang, LV. Sequist, V. Hirsh, K. O'Byrne, N. Yamamoto, D. Massey, M. Shahidi, V. Zazulina, T. Mok. Efficacy of afatinib vs. chemotherapy in treatment-naïve patients with non-small cell lung cancer (NSCLC) harbouring activating EGFR mutations with or without metastatic brain disease. 15th World Conference on Lung Cancer, 2013.10.27-2013.10.31, Sydney, New South Wales, Australia

24. H. Kenmotsu, S. Niho, T. Ito, Y. Ishikawa, M. Noguchi, H. Tada, I. Sekine, S. Watanabe, M. Yoshimura, N. Yamamoto, F. Oshita, K. Kubota, K. Nagai. A pilot study of adjuvant chemotherapy with irinotecan and cisplatin for completely resected high grade pulmonary neuroendocrine carcinona (Large cell neuroendocrine carcinoma and small cell lung cancer). 15th World Conference on Lung Cancer, 2013.10.27-2013.10.31, Sydney, New South Wales, Australia

25. K. Takayama, M. Fujita, A. Ono, K. Takeda, T. Ohira, H. Isobe, N. Ebi, K. Tateishi, N. Yamamoto, Y. Nakanishi, K. Tamura. A prospective multicenter observational study of chemotherapy induced nausea and vomiting in lung cancer patients. 15th World Conference on Lung Cancer, 2013.10.27-2013.10.31, Sydney, New South Wales, Australia

26. JC. Yang, LV. Sequist, SL. Geater, CM. Tsai, TS. Mok, M. Schuler, N. Yamamoto, D. Massey, V. Zazulina, YL. Wu. Activity of afatinib in uncommon epidermal growth factor receptor (EGFR) mutations: Findings

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from three trials of afatinib in EGFR mutation-positive lung cancer. 15th World Conference on Lung Cancer, 2013.10.27-2013.10.31, Sydney, New South Wales, Australia

27. T. Takahashi, N. Yamamoto, K. Takeda, S. Kudoh, K. Nakagawa, T. Hida, K. Kiura, N. Takigawa, T. Seto, H. Tsukuda, N. Masuda, M. Fukuoka. Dose adjustment of single agent amrubicin in lung cancer patients with impaired hepatic function. 15th World Conference on Lung Cancer, 2013.10.27-2013.10.31, Sydney, New South Wales, Australia

28. T. Naito, N. Yamamoto, F. Ohyanagi, T. Horai, A. Horiike, T. Kozuka, H. Murakami, H. Harada, T. Takahashi, Y. Nakamura, M. Nishio. Long-term results of a phase II trial of S-1 and cisplatin with concurrent thoracic radiotherapy for locally advanced non-small cell lung cancer. 15th World Conference on Lung Cancer, 2013.10.27-2013.10.31, Sydney, New South Wales, Australia

29. H. Imai, T. Takahashi, M. Serizawa, K. Mori, A. Ono, H. Akamatsu, T. Taira, Y. Nakamura, H. Kenmotsu, T. Naito, H. Murakami, Y. Koh, M. Endo, T. Nakajima, N. Yamamoto. Pharmacogenetic study of Japanese patients with advanced non-squamous non-small cell lung cancer treated with pemetrexed plus cisplatin. 15th World Conference on Lung Cancer, 2013.10.27-2013.10.31, Sydney, New South Wales, Australia

30. K. Hayakawa, Y. Nishimura, H. Harada, T. Soejima, K. Tsujino, T. Kozuka, M. Tanaka, T. Sasaki, N. Yamamoto, K. Nakagawa. Phase II study of nimotuzumab in combination with concurrent chemoradiotherapy (CRT) in patients with locally advanced non-small cell lung cancer (NSCLC). 15th World Conference on Lung Cancer, 2013.10.27-2013.10.31, Sydney, New South Wales, Australia

31. K. Goto, N. Yamamoto, Y. Ohe, M. Kusmoto, M. Endo, Y. Toratani, M. Fukuoka. Avastin® for advanced or recurrent non-squamous non-small cell lung cancer: A nested case control study exploring risk factors for hemoptysis in Japan. 15th World Conference on Lung Cancer, 2013.10.27-2013.10.31, Sydney, New South Wales, Australia

32. LV. Sequist, JC. Yang, N. Yamamoto, K. O'Byrne, M. Schuler, T. Mok, SL. Geater, D. Massey, S. Wind, D. O'Brien, R. Lorence, YL. Wu. Comparative safety profile of afatinib in Asian and non-Asian patients with EGFR mutation-positive (EGFR M+) non-small cell lung cancer (NSCLC). 15th World Conference on Lung Cancer, 2013.10.27-2013.10.31, Sydney, New

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South Wales, Australia 33. R. Ko, H. Kenmotsu, Y. Hisamatsu, H. Akamatsu, S. Omori, K. Nakashima,

T. Oyakawa, K. Wakuda, H. Imai, A. Ono, T. Taira, H. Murakami, T. Naito, K. Mori, M. Endo, T. Takahashi. The effect of gefitinib in patients with postoperative recurrent non-small cell lung cancer harbouring mutations of the epidermal growth factor receptor. 15th World Conference on Lung Cancer, 201310.27-2013.10.31, Sydney, New South Wales, Australia

34. K. Matsunaga, A. Oka, T. Kamei, Y. Sakamoto, Y. Minakata. Ongoing Allergic Rhinitis Impairs Asthma Control By Enhancing The Lower Airway Inflammation. The 18th Congress of the Asian Pacific Society of Respirology, 2013.11.12, Yokohama, Japan

国内シンポジウム・ワークショップ・特別講演・学術講演等

[シンポジウム・ワークショップ・特別講演] 1. K. Matsunaga, H. Kawabata, K. Akamatsu, T. Hirano, Y. Minakata, M.

Ichinose: Difference in Time-course of Improvement in Asthma Control Measures between Budesonide and Budesonide/Formoterol. The 53nd Annual Meeting of The Japanese Respiratory Society (English Poster Discussion), 2013.04.19, Tokyo, Japan

2. 澤祥幸, 江口研二, 千場博, 山本英彦, 中村慎一郎, 山本信之, 里内美弥子, 武田晃司, 岩本康男, 中西洋一: 患者・市民との標準治療の共有-NPO臨床試

験グループによる肺がん患者向けガイドブック「よくわかる肺がん」の作製

と活用. 第 11回日本臨床腫瘍学会学術集会, 仙台市, 2013.08.29 3. 宿谷威仁, 芹澤昌邦, 阿部将人, 赤松弘朗, 内藤立暁, 村上晴泰, 高橋利明,

中島孝, 洪泰浩, 山本信之: 悪性胸膜中皮腫に対する遺伝子異常解析. 第 11

回日本臨床腫瘍学会学術集会, 仙台市, 2013.08.29 4. 釼持広知, 洪泰浩, 芹澤昌邦, 井坂光宏, 盛啓太, 高橋利明, 遠藤正浩, 中島

孝, 大出泰久, 山本信之: 静岡がんセンターにおける肺がん患者の網羅的遺

伝子変異解析. 第 11 回日本臨床腫瘍学会学術集会, 仙台市, 2013.08.30 5. 樋田豊明, 木浦勝行, 西尾誠人, 瀬戸貴司, 中川和彦, 前門戸任, 井上彰, 山

本信之, 竹内賢吾, 田村友秀: ALK 陽性の非小細胞肺癌患者に対する

CH5424802 の第 I/II 相臨床試験(AF-001JP). 第 11 回日本臨床腫瘍学会学

術集会, 仙台市, 2013.8.30 6. 釼持広知, 芹澤昌邦, 洪泰浩, 井坂光宏, 遠藤正浩, 中島孝, 大出泰久, 高橋

利明, 山本信之: 肺癌における遺伝子プロファイリング. 第 54 回日本肺癌学

会総会, 東京, 2013.11.21

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7. 大柳文義, 山本信之, 堀池篤, 宝来威, 小塚拓洋, 村上晴泰, 原田英幸, 高橋

利明, 中村有希子, 西尾誠人: 切除不能局所進行非小細胞肺がんに対する

CDDP/TS-1 併用化学療法と胸部同時放射線照射第 II 相試験の長期成績. 第54 回日本肺癌学会総会, 東京, 2013.11.22

8. 釼持広知, 仁保誠治, 伊東猛雄, 石川雄一, 多田弘人, 関根郁夫, 渡辺俊一, 吉村雅裕, 山本信之, 尾下文浩, 久保田薫, 永井完治: 高悪性度神経内分泌癌

に対するシスプラチン+塩酸イリノテカンの術後補助化学療法の pilot study(生存解析). 第 54 回日本肺癌学会総会, 東京, 2013.11.22

9. 澤祥幸, 中西洋一, 坂英雄, 山本信之, 里内美弥子, 倉田宝保, 瀬戸貴司, 坪井正博, 浦田佳子, 宿谷威仁, 山中竹春, 光冨徹哉, 西村恭昌, 西尾和人, 高田實, 中村慎一郎, 中川和彦, 西條長宏, 福岡正博: 日本版「Methods in Clinical Cancer Research」虎の穴による若手肺癌研究者の教育. 第 54 回日

本肺癌学会総会, 東京, 2013.11.22 10. 松永和人, 岡亜早子, 亀井雅, 坂本幸裕, 平野綱彦, 赤松啓一郎: アレルギー

性鼻炎と喘息: 上気道と下気道の関連機序の検討. 第 63 回日本アレルギー学

会秋季学術大会 (ミニシンポジウム), 東京, 2013.11.30 全国学会

1. 南方良章, 本多雄一, 神田匡兄, 市川朋宏, 赤松啓一郎, 小荒井晃, 平野綱彦, 中西正典, 杉浦久敏, 松永和人, 一ノ瀬正和: COPD 患者の活動性低下の強度

別評価とその特徴. 第 53 回日本呼吸器学会学術講演会, 東京, 2013.04.19-21 2. 赤松啓一郎, 松永和人, 宮武明彦, 藤田君ゑ, 一ノ瀬正和: 重症喘息における

閉塞性障害の長期的な進行経過. 第 53 回日本呼吸器学会学術講演会, 東京, 2013.04.19-21

3. 市川朋宏, 杉浦久敏, 小荒井晃, 菊池崇史, 金井一修, 松永和人, 南方良章, 一ノ瀬正和: Toll 様受容体 3 (TLR-3)の活性化は誘導型 NO 合成酵素(iNOS)の発現を介して肺線維芽細胞からの matrix metalloproteinase(MMP)の産生

を亢進する. 第 53 回日本呼吸器学会学術講演会, 東京, 2013.04.19-21 4. 菊池崇史, 杉浦久敏, 小荒井晃, 市川朋宏, 南方良章, 松永和人, 中西正典,

平野綱彦, 赤松啓一郎, 川端宏樹, 平松政高, 金井一修, 森下友紀子, 岡亜早

子, 一ノ瀬正和: 27-hydroxycholesterol が肺線維芽細胞における matrix metalloproteinase 産生に与える影響についての検討. 第 53 回日本呼吸器学

会学術講演会, 東京, 2013.04.19-21 5. 金井一修, 小荒井晃, 杉浦久敏, 市川朋宏, 菊池崇史, 南方良章, 一ノ瀬正和:

Toll 様受容体刺激による気道上皮におけるムチン産生およびその機序に関す

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る検討. 第 53 回日本呼吸器学会学術講演会, 東京, 2013.04.19-21 6. 解良恭一, 芹澤昌邦, 洪泰浩, 高橋利明, 遠藤正浩, 砂長則明, 岩橋靖樹, 久

田剛志, 石塚全, 山本信之: 悪性胸膜中皮腫における FDG 集積の生物学的特

性. 第 53 回日本呼吸器学会学術講演会, 東京, 2013.04.19-21 7. 宿谷威仁, 高橋利明, 時任高章, 今井久雄, 小野哲, 赤松弘朗, 太良哲彦, 釼

持広知, 内藤立暁, 村上晴泰, 遠藤正浩, 山本信之: 悪性胸膜中皮腫に対する

シスプラチン+ペメトレキシド療法とシスプラチン+ゲムシタビン療法との

比較検討. 第 53 回日本呼吸器学会学術講演会, 東京, 2013.04.19-21 8. 前島悦子, 古川加奈子, 前島伸一郎, 山内康平: 口腔衛生が関節リウマチの病

態に及ぼす影響に関する検討. 第 57 回日本リウマチ学会総会・学術集会・国

際リウマチシンポジウム, 京都市, 2013.04.25 9. 岡亜早子, 松永和人, 平野綱彦, 南方良章: 低肺機能を契機に受診し非典型的

な臨床経過を呈した喘息症例. 第 25 回日本アレルギー学会春季臨床大会, 横浜市, 2013.05.12

10. 東み幸, 瀧口良重, 井上良子, 中塚賢一, 岡田真由美, 橋本安貴子, 森井眞治, 大石博晃, 平野綱彦, 三家登喜夫: 慢性閉塞性肺疾患における肺拡散能力の

意義. 第 62 回日本医学検査学会, 高松市, 2013.05.18 11. 上田弘樹, 下野千草, 山上裕機: 地域医療におけるがん診療体制の強化にむ

けた化学療法部会の活動. 第 11 回日本臨床腫瘍学会学術集会, 仙台市, 2013.08.29-31

12. Yamamoto N, Nokihara H, Han JY, Hida T, Riely GJ, Baldini E, Salvatore S, Horn L, Polli A、Satouchi M: Crizotinib vs. pemetrexed or docetaxel in advanced ALK+ non-small cell lung cancer: subgroup analysis in PROFILE 1007. 第 11 回日本臨床腫瘍学会学術集会, 仙台市, 2013.08.29-31

13. Akamatsu H, Mori K, Harada H, Imai H, Ono A, Taira T, Kenmotsu H, Naito T, Murakami H, and Takahashi T: Surrogate markers of survival in locally advanced Non-Small Cell Lung Cancer: Meta-analysis from randomized trials. 第 11 回日本臨床腫瘍学会学術集会, 仙台市, 2013.08.29-31

14. 時任高章, 村上晴泰, 今井久雄, 赤松弘朗, 太良哲彦, 小野哲, 釼持広知, 内藤立暁, 高橋利明, 山本信之: Advance Care Planning for advanced non-small cell lung cancer patients / 4 期非小細胞肺癌 (NSCLC) に対する

Advance Care Planning (ACP) の検討. 第 11 回日本臨床腫瘍学会学術集会, 仙台市, 2013.08.29-31

15. 相羽惠介, 田村和夫, 佐伯俊昭, 中西洋一, 嘉村利治, 馬場秀夫, 山本信之, 平田公一, 前原喜彦, 北島政樹: がん薬物療法誘発悪心嘔吐に関する患者お

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よび医療者意識の全国調査 CINV 研究会. 第 11 回日本臨床腫瘍学会学術集

会, 仙台市, 2013.08.29-31 16. 鈴木賢一, 橋本浩伸, 水野靖也, 宇良敬, 荒川雄一郎, 森清志, 玉木慎也, 高

橋康雄, 山中竹春, 山本信之: シスプラチン投与後の化学療法誘発性悪心嘔

吐予防に対する、パロノセトロンとグラニセトロンの第三相試験. 第 11 回日

本臨床腫瘍学会学術集会, 仙台市, 2013.08.29-31 17. 金田裕靖, 里内美弥子, 千葉康敬, 山本信之, 西村恭昌, 藤阪保仁, 工藤新三,

樋田豊明, 安宅信二, 中川和彦: Additional analysis of WJTOG0105 comparing second and third-generation regimens with TRT in unresectable stage III NSCLC. 第 11 回日本臨床腫瘍学会学術集会, 仙台市, 2013.08.29-31

18. 今井久雄, 宿谷威仁, 吉野麗子, 村木慶子, 内藤立暁, 村上晴泰, 富澤由雄, 高橋利明, 高橋和久, 山本信之: 術後補助化学療法施行後、再発非小細胞肺癌

の一次治療としてプラチナ製剤を含む併用化学療法の有効性と安全性の検討. 第 11 回日本臨床腫瘍学会学術集会, 仙台市, 2013.08.29-31

19. 太良哲彦, 釼持広知, 洪泰浩, 高橋利明, 村上晴泰, 内藤立暁, 小野哲, 赤松

弘朗, 今井久雄, 山本信之: Comparison of lung cancer multiplexed molecular profiling between biopsy samples and surgically resected samples. 第 11 回日本臨床腫瘍学会学術集会, 仙台市, 2013.08.29-31

20. Akamatsu H, Kenmotsu H, Serizawa M, Koh Y, Ono A, Imai H, Naito T, Murakami H, Ohde Y, Endo M, Nakajima T, Takahashi T, and Yamamoto N: Multiplexed molecular profiling for advanced thoracic malignancies with pleural and pericardial effusion. 72nd Annual Meeting of the Japanese Cancer Association, Yokohama, 2013.10.03

21. 芹澤昌邦, 洪泰浩, 釼持広知, 井坂光宏, 成岡茜, 鈴木淳子, 阿部将人, 林勇, 遠藤正浩, 中島孝, 大出泰久, 高橋利明, 山本信之: 肺腺癌における個別化医

療の推進を目的した体細胞変異プロファイリング. 第72回日本癌学会学術総

会, 横浜市, 2013.10.03-05 22. 井坂光宏, 芹澤昌邦, 洪泰浩, 釼持広知, 高橋祥司, 馬庭知弘, 内藤立暁, 村

上晴泰, 遠藤正浩, 中島孝, 大出泰久, 高橋利明, 山本信之: 次世代シーケン

サーによる非小細胞肺癌切除例の体細胞変異プロファイリング. 第72回日本

癌学会学術総会, 横浜市, 2013.10.03-05 23. 釼持広知, 芹澤昌邦, 洪泰浩, 井坂光宏, 阿部将人, 杉野隆, 馬庭知弘, 高橋

祥司, 遠藤正浩, 中島孝, 大出泰久, 高橋利明, 山本信之: 肺扁平上皮癌にお

ける遺伝子プロファイリング. 第 72 回日本癌学会学術総会, 横浜市, 2013.10.03-05

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24. 和久田一茂, 釼持広知, 芹澤昌邦, 洪泰浩, 井坂光宏, 小野哲, 内藤立暁, 盛啓太, 遠藤正浩, 中島孝, 大出泰久, 高橋利明, 山本信之: 小細胞肺癌におけ

る遺伝子プロファイリングの検討. 第 72 回日本癌学会学術総会, 横浜市, 2013.10.03-05

25. 赤松弘朗, 釼持広知, 芹澤昌邦, 洪泰浩, 小野哲, 今井久雄, 内藤立暁, 村上

晴泰, 大出泰久, 遠藤正浩, 中島孝, 高橋利明, 山本信之: 胸水・心嚢水を用

いた、胸部悪性腫瘍における網羅的分子プロファイリングの試み. 第 72 回日

本癌学会学術総会, 横浜市, 2013.10.03-05 26. 太良哲彦, 釼持広知, 芹澤昌邦, 洪泰浩, 井坂光宏, 村上晴泰, 盛啓太, 遠藤

正浩, 中島孝, 大出泰久, 高橋利明, 山本信之: ホルマリン固定パラフィン包

埋生理検体と外科的切除凍結組織における肺癌分子プロファイリングの比較. 第 72 回日本癌学会学術総会, 横浜市, 2013.10.03-05

27. 阿部将人, 杉野隆, 村松浩二, 芹澤昌邦, 洪泰浩, 赤松弘朗, 剣持広知, 井坂

光弘, 大出泰久, 高橋利明, 山本信之, 中島孝: 肺扁平上皮癌における PTEN発現状況の免疫組織化学的検出. 第 72 回日本癌学会学術総会, 横浜市, 2013.10.03-05

28. 宿谷威仁, 芹澤昌邦, 赤松弘朗, 時任高章, 今井久雄, 小野哲, 太良哲彦, 釼持広知, 内藤立暁, 村上晴泰, 高橋利明, 洪泰浩, 山本信之: 悪性胸膜中皮腫

に対する遺伝子異常解析. 第 72 回日本癌学会学術総会, 横浜市, 2013.10.03-05

29. 今井久雄, 高橋利明, 芹澤昌邦, 盛啓太, 中村有希子, 釼持広知, 内藤立暁, 村上晴泰, 洪泰浩, 遠藤正浩, 中島孝, 山本信之: 進行非小細胞肺がんに対す

るPemetrexedの効果および毒性に関する遺伝子多型の影響. 第 72回日本癌

学会学術総会, 横浜市, 2013.10.03-05 30. 本多雄一, 南方良章, 杉野亮人, 森下友紀子, 山本信之: 在宅酸素療法患者に

対するフライングディスク競技の忍容性と活動強度に関する研究. 第23回日

本呼吸ケア・リハビリテーション学会, 東京, 2013.10.11 31. 上田弘樹, 下野千草, 山上裕機: XELOX におけるパロノセトロンを用いた制

吐療法の DXM 減量の後方視的検討. 第 51 回日本癌治療学会学術集会, 京都

市, 2013.10.24 32. 山本信之, 後藤功一, 大江裕一郎, 楠木昌彦, 遠藤正浩, 清水綾香, 福岡正博:

アバスチン®非小細胞肺癌における喀血発現リスク因子の探索を目的とした

ネステッドコントロール研究. 第 54 回日本肺癌学会総会, 東京, 2013.11.21-22

33. 芹澤昌邦, 洪泰浩, 釼持広知, 井坂光宏, 成岡茜, 鈴木淳子, 和久田一茂, 阿部将人, 林勇, 遠藤正浩, 中島孝, 大出泰久, 赤松弘朗, 村上晴泰, 高橋利明,

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山本信之: 肺腺癌における個別化医療の推進を目的とした体細胞変異プロフ

ァイリング. 第 54 回日本肺癌学会総会, 東京, 2013.11.21-22 34. 赤松弘朗, 剣持広知, 芹澤昌邦, 洪泰浩, 小野哲, 今井久雄, 太良哲彦, 内藤

立暁, 村上晴泰, 大出泰久, 遠藤正浩, 中島孝, 高橋利明, 山本信之: 胸水・心

嚢水を用いた, 胸部悪性腫瘍における網羅的分子プロファイリングの検討. 第 54 回日本肺癌学会総会, 東京, 2013.11. 21-22

35. 赤松弘朗, 中島和寿, 親川拓也, 内藤立暁, 盛啓太, 今井久雄, 小野哲, 太良

哲彦, 剣持広知, 村上晴泰, 遠藤正浩, 高橋利明: 高齢進行非小細胞肺癌にお

ける初回化学療法の無増悪生存/増悪後生存期間と全生存期間の相関に関す

る検討. 第 54 回日本肺癌学会総会, 東京, 2013.11.21-22 36. 瀧口友美, 大柳文義, 橋本浩伸, 中尾将彦, 武田晃司, 東加奈子, 藤原季美子,

山中竹春, 鈴木賢一, 山本信之: 高度催吐性化学療法におけるグラニセトロ

ン(Gra)とパロノセトロン(Paro)の二重盲検無作為化比較試験. 第 54 回日本

肺癌学会総会, 東京, 2013.11.21-22 37. 藤田昌樹, 高山浩一, 小野哲, 武田晃司, 大平達夫, 礒部宏, 海老規之, 立石

一成, 山本信之, 中西洋一, 田村和夫: 肺がん化学療法時の悪心・嘔吐観察研

究:がん治療と CINV 研究会による多施設共同研究. 第 54 回日本肺癌学会総

会, 東京, 2013.11.21-22 38. 今井久雄, 芹澤昌邦, 高橋利明, 盛啓太, 小野哲, 赤松弘朗, 太良哲彦, 釼持

広知, 内藤立暁, 村上晴泰, 洪泰浩, 遠藤正浩, 山本信之: 進行非扁平上皮非

小細胞肺がんに対する Pemetrexed の効果および毒性に関する遺伝子多型の

影響. 第 54 回日本肺癌学会総会, 東京, 2013.11.21-22 39. 駄賀晴子, 武田晃司, 山本信之, 工藤新三, 中川和彦, 樋田豊明, 木浦勝行,

瀧川奈義夫, 瀬戸貴司, 米坂仁雄, 福岡正博, 益田典幸: 肝機能異常を有する

肺癌患者を対象としたアムルビシン塩酸塩の薬物動態試験. 第54回日本肺癌

学会総会, 東京, 2013.11.21-22 40. 釼持広知, 芹澤昌邦, 洪泰浩, 井坂光宏, 阿部将人, 杉野隆, 馬庭知弘, 高橋

祥司, 太良哲彦, 遠藤正浩, 中島孝, 大出泰久, 高橋利明, 山本信之: 肺扁平

上皮癌における遺伝子プロファイリングの検討. 第 54 回日本肺癌学会総会, 東京, 2013.11.21-22

41. 馬庭知弘, 芹澤昌邦, 洪泰浩, 井坂光宏,、釼持広知, 高橋祥司, 遠藤正浩, 中島孝, 大出泰久, 高橋利明, 山本信之: 間質性肺炎合併非小細胞肺癌における

遺伝子プロファイルの検討. 第 54 回日本肺癌学会総会, 東京, 2013.11.21-22

42. 金田裕靖, 中川和彦, 工藤慶太, 西尾誠人, 村上晴泰, 山本信之, 堀之内秀仁, 田村友秀: Phase I study of patritumab (U3-1287) in combination with

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erlotinib in NSCLC patients. 第 54 回日本肺癌学会総会, 東京, 2013.11.21-22

43. 三角祐生, 下川恒生, 堀池篤, 大柳文義, 西尾誠人, 釼持広知, 村上晴泰, 高橋利明, 山本信之, 岡本浩明: 高齢者の進展型小細胞肺がんに対するカルボ

プラチン+イリノテカン併用療法の feasibility study 最終報告. 第 54 回日本

肺癌学会総会, 東京, 2013.11.21-22 44. 太良哲彦, 村上晴泰, 内藤立暁, 釼持広知, 今井久雄, 小野哲, 赤松弘朗, 宿

谷威仁, 久松靖史, 大森翔太, 盛啓太, 原田英幸, 遠藤正浩, 中島孝, 高橋利

明, 山本信之: 局所進行非小細胞肺癌における p16INK4Aの予後因子としての

検討. 第 54 回日本肺癌学会総会, 東京, 2013.11.21-22 45. 井坂光宏, 芹澤昌邦, 洪泰浩, 釼持広知, 馬庭知弘, 高橋祥司, 遠藤正浩, 中

島孝, 大出泰久, 高橋利明, 山本信之: 次世代シーケンサーによる肺腺癌切除

例の遺伝子プロファイルと病理組織像との検討. 第 54 回日本肺癌学会総会, 東京, 2013.11.21-22

46. 和久田一茂, 釼持広知, 芹澤昌邦, 洪泰浩, 井坂光宏, 今井久雄, 小野哲, 内藤立暁, 盛啓太, 遠藤正浩, 中島孝, 大出泰久, 高橋利明, 山本信之: 小細胞

肺癌の分子プロファイリングの検討. 第 54 回日本肺癌学会総会, 東京, 2013.11.21-22

47. 阿部将人, 杉野隆, 村松浩二, 芹澤昌邦, 洪泰浩, 赤松弘朗, 剣持広知, 井坂

光弘, 大出泰久, 高橋利明, 山本信之, 中島孝: 肺扁平上皮癌における PTEN発現状況の免疫組織化学的検出. 第 54 回日本肺癌学会総会, 東京, 2013.11.21-22

地方学会

1. 太地良, 金井一修, 岡亜早子, 森下友紀子, 川端宏樹, 菊池崇史, 平松政高, 市川朋宏, 赤松啓一郎, 平野綱彦, 中西正典, 松永和人, 南方良章, 山本信之: 当院における超音波気管支鏡ガイド下針生検 (EBUS-TBNA) 施行症例の検

討. 第 94 回日本呼吸器内視鏡学会近畿支部会, 大阪市, 2013.11.30 2. 太地良, 杉本真衣美, 岡亜早子, 森下友紀子, 金井一修, 川端宏樹, 菊池崇史,

平松政高, 市川朋宏, 赤松啓一郎, 平野綱彦, 中西正典, 松永和人, 南方良章, 山本信之, 中村靖司: IgG4 関連疾患による胸膜炎が疑われた 1 例. 第 82 回日

本呼吸器学会近畿地方会, 大阪市, 2013.12.07 3. 柴木亮太, 田中彩加, 岡亜早子, 森下友紀子, 金井一修, 川端宏樹, 菊池崇史,

平松政高, 赤松弘朗, 市川朋宏, 赤松啓一郎, 平野綱彦, 中西正典, 松永和人, 南方良章, 山本信之: 胸水と肺塞栓症を認めた IgG4 関連呼吸器疾患の 1 例. 第 82 回日本呼吸器学会近畿地方会, 大阪市, 2013.12.07

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4. 平田桂資, 森下友紀子, 市川朋宏, 川端宏樹, 赤松啓一郎, 中西正典, 南方良

章, 山本信之: 癌性リンパ管症で発症した結腸癌の一例. 第 82 回日本呼吸器

学会近畿地方会, 大阪市, 2013.12.07

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