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22 September 2015 CKD and Urology

22 September 2015. Paired retroperitoneal structures Filtration and excretion of metabolic waste products Regulation of electrolytes, fluid, and acid-base

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Page 1: 22 September 2015. Paired retroperitoneal structures Filtration and excretion of metabolic waste products Regulation of electrolytes, fluid, and acid-base

22 September 2015

CKD and Urology

Page 2: 22 September 2015. Paired retroperitoneal structures Filtration and excretion of metabolic waste products Regulation of electrolytes, fluid, and acid-base
Page 3: 22 September 2015. Paired retroperitoneal structures Filtration and excretion of metabolic waste products Regulation of electrolytes, fluid, and acid-base

KidneysPaired retroperitoneal structuresFiltration and excretion of metabolic waste

productsRegulation of electrolytes, fluid, and acid-

base balanceStimulation of RBC production

Page 4: 22 September 2015. Paired retroperitoneal structures Filtration and excretion of metabolic waste products Regulation of electrolytes, fluid, and acid-base

Kidneys

Page 5: 22 September 2015. Paired retroperitoneal structures Filtration and excretion of metabolic waste products Regulation of electrolytes, fluid, and acid-base

Kidneys

Page 6: 22 September 2015. Paired retroperitoneal structures Filtration and excretion of metabolic waste products Regulation of electrolytes, fluid, and acid-base

Kidneys

Page 7: 22 September 2015. Paired retroperitoneal structures Filtration and excretion of metabolic waste products Regulation of electrolytes, fluid, and acid-base

NephrolithiasisRenal calculiA common cause of renal failureSupersaturation of the urine by stone-forming

constituentsCalcium, oxalate, and uric acidDehydration, low fluid intake

Page 8: 22 September 2015. Paired retroperitoneal structures Filtration and excretion of metabolic waste products Regulation of electrolytes, fluid, and acid-base

Kidney stones can cause kidney damage in two primary ways

An untreated obstructing stone that causes persistent severe blockage

Infection related stones can lead to ongoing chronic urinary tract infections that cause damage slowly through inflammation and scarring of the kidney tissue

Nephrolithiasis

Page 9: 22 September 2015. Paired retroperitoneal structures Filtration and excretion of metabolic waste products Regulation of electrolytes, fluid, and acid-base

Nephrolithiasis

Page 10: 22 September 2015. Paired retroperitoneal structures Filtration and excretion of metabolic waste products Regulation of electrolytes, fluid, and acid-base

Nephrolithiasis

Page 11: 22 September 2015. Paired retroperitoneal structures Filtration and excretion of metabolic waste products Regulation of electrolytes, fluid, and acid-base

Nephrolithiasis

Page 12: 22 September 2015. Paired retroperitoneal structures Filtration and excretion of metabolic waste products Regulation of electrolytes, fluid, and acid-base
Page 13: 22 September 2015. Paired retroperitoneal structures Filtration and excretion of metabolic waste products Regulation of electrolytes, fluid, and acid-base
Page 14: 22 September 2015. Paired retroperitoneal structures Filtration and excretion of metabolic waste products Regulation of electrolytes, fluid, and acid-base

PresentationsPainHematuriaUTIRenal failureAsymptomatic

Page 15: 22 September 2015. Paired retroperitoneal structures Filtration and excretion of metabolic waste products Regulation of electrolytes, fluid, and acid-base
Page 16: 22 September 2015. Paired retroperitoneal structures Filtration and excretion of metabolic waste products Regulation of electrolytes, fluid, and acid-base

InvestigationsUrine examinationPlain KUBBUN, CreatinineIVP CT scan

Page 17: 22 September 2015. Paired retroperitoneal structures Filtration and excretion of metabolic waste products Regulation of electrolytes, fluid, and acid-base

Plain KUB

Page 18: 22 September 2015. Paired retroperitoneal structures Filtration and excretion of metabolic waste products Regulation of electrolytes, fluid, and acid-base

IVP

Page 19: 22 September 2015. Paired retroperitoneal structures Filtration and excretion of metabolic waste products Regulation of electrolytes, fluid, and acid-base

IVP

Page 20: 22 September 2015. Paired retroperitoneal structures Filtration and excretion of metabolic waste products Regulation of electrolytes, fluid, and acid-base

Treatment of renal calculi

Conservative, medicationESWL ( extracorporeal shockwave lithotripsy )RIRS ( retrograde intrarenal surgery )PCNL ( percutaneous nephrolithotomy )Open Sx ( Anatrophic nephrolithotomy,

Pyelolithotomy )Nephrectomy

Page 21: 22 September 2015. Paired retroperitoneal structures Filtration and excretion of metabolic waste products Regulation of electrolytes, fluid, and acid-base

ESWL

Page 22: 22 September 2015. Paired retroperitoneal structures Filtration and excretion of metabolic waste products Regulation of electrolytes, fluid, and acid-base

RIRS

Page 23: 22 September 2015. Paired retroperitoneal structures Filtration and excretion of metabolic waste products Regulation of electrolytes, fluid, and acid-base

PCNLPercutaneous nephrolithotomyPRS : Percutaneous Renal SurgeryA minimally invasive technique to access the

kidney to remove large stones (>2cm) or stones

Small puncture wound

Page 24: 22 September 2015. Paired retroperitoneal structures Filtration and excretion of metabolic waste products Regulation of electrolytes, fluid, and acid-base

PCNL

Page 25: 22 September 2015. Paired retroperitoneal structures Filtration and excretion of metabolic waste products Regulation of electrolytes, fluid, and acid-base

ANL

Page 26: 22 September 2015. Paired retroperitoneal structures Filtration and excretion of metabolic waste products Regulation of electrolytes, fluid, and acid-base

Obstructive uropathy

Page 27: 22 September 2015. Paired retroperitoneal structures Filtration and excretion of metabolic waste products Regulation of electrolytes, fluid, and acid-base

Obstructive uropathyBlockage of the flow of urine out of the bodyCommon cause of acute and chronic renal

failureIntrinsic and extrinsic causeUrine stasis, infection, stone formation,

anatomical changes, renal deterioration

Page 28: 22 September 2015. Paired retroperitoneal structures Filtration and excretion of metabolic waste products Regulation of electrolytes, fluid, and acid-base

Obstructive uropathy Post-renal renal failureSupravesical obstruction (Bilateral ureteral

obstruction) infravesical obstruction (Bladder outlet

obstruction)HydronephrosisSurgical anuriaOverflow incontinence

Page 29: 22 September 2015. Paired retroperitoneal structures Filtration and excretion of metabolic waste products Regulation of electrolytes, fluid, and acid-base

HintUnderlying diseasesPrevious renal functionSigns of CKDLUTSHistory of KUB stone

Page 30: 22 September 2015. Paired retroperitoneal structures Filtration and excretion of metabolic waste products Regulation of electrolytes, fluid, and acid-base

InvestigationsCBCBUN, Cr., electrolyteUAPlain KUBUltrasound

Page 31: 22 September 2015. Paired retroperitoneal structures Filtration and excretion of metabolic waste products Regulation of electrolytes, fluid, and acid-base

Renal UltrasonographyHydronephrosis : a hallmark of urinary tract

obstructionMeasurement of kidney size and echogenicity

as part of an evaluation of chronic kidney disease

No exposure to radiationInterpretation is operator-dependent

Page 32: 22 September 2015. Paired retroperitoneal structures Filtration and excretion of metabolic waste products Regulation of electrolytes, fluid, and acid-base
Page 33: 22 September 2015. Paired retroperitoneal structures Filtration and excretion of metabolic waste products Regulation of electrolytes, fluid, and acid-base
Page 34: 22 September 2015. Paired retroperitoneal structures Filtration and excretion of metabolic waste products Regulation of electrolytes, fluid, and acid-base
Page 35: 22 September 2015. Paired retroperitoneal structures Filtration and excretion of metabolic waste products Regulation of electrolytes, fluid, and acid-base
Page 36: 22 September 2015. Paired retroperitoneal structures Filtration and excretion of metabolic waste products Regulation of electrolytes, fluid, and acid-base

Obstructive uropathyUrinary diversionFoley catheterIntake, output monitoringNephrotoxics avoidanceElectrolyte imbalance

Page 37: 22 September 2015. Paired retroperitoneal structures Filtration and excretion of metabolic waste products Regulation of electrolytes, fluid, and acid-base

Urinary diversionA surgical procedure that reroutes the

normal flow of urine out of the bodyUrine cannot flow out of the body External diversion (nephrostomy)Internal diversion (double J stent)

Page 38: 22 September 2015. Paired retroperitoneal structures Filtration and excretion of metabolic waste products Regulation of electrolytes, fluid, and acid-base

nephrostomy

Page 39: 22 September 2015. Paired retroperitoneal structures Filtration and excretion of metabolic waste products Regulation of electrolytes, fluid, and acid-base

Double J stent

Page 40: 22 September 2015. Paired retroperitoneal structures Filtration and excretion of metabolic waste products Regulation of electrolytes, fluid, and acid-base

Bladder outlet obstructionA blockage at the base of the bladder that

reduces or prevents the flow of urineBPH, Urethral stricture, Urethral calculiLUTS (lower urinary tract symptoms)Mechanical, FunctionalFoley catheter

Page 41: 22 September 2015. Paired retroperitoneal structures Filtration and excretion of metabolic waste products Regulation of electrolytes, fluid, and acid-base
Page 42: 22 September 2015. Paired retroperitoneal structures Filtration and excretion of metabolic waste products Regulation of electrolytes, fluid, and acid-base

Thank You