8
Hypertension = x
140 mmHg 90 mmHg
Systolic/diastolic
2 (essential HTN 95%) 30% (secondary HTN 5 %), ,
- , ,
- , , , , , , , : 90~95% : , , , , 3
1) : 2 2) : 1 3) 1 : 1-2 4) 2 - 180/110mmHg , 1 - 1
Effects of Hypertension
1. , , , 2. 3. , (occipital pain), , 4. 5. 6. , 5 20/10 mmHg - ,
, ,
30 ~ 45% 20 ~ 25% 50% Intubation CVA risk Desflurane Heartrate,
BP
: , HDL, LDL, . : , , , , , . BUN : , , ( )
X-ray- . - X-ray .8 (140/90mmHg) ( , 130/80mmHg )1 (SBP140~159
or DBP90~99mmHg)Thiazide *
*** , 2 (SBP 1.4 .- ; , , , ,
Furosemide (Lasix)- loop diuretics, - 20-80mg qd (
600mg/day)
Spironolactone (Aldactone)- Aldosterone antagonist- 1 25 mg ~ 50
mg- (cardiac remodeling )-
-methyldopa, clonidine, guanabenz 2-adrenaline , , , , 1
adrenaline Prazocin, doxazosin, terazocin 1 , , , , , ,
1 adrenaline -adrenaline , - Propranolol 1 Metoprolol,
acebutolol, atenolol , renin , , , , , ,
-adrenaline Atenolol (Tenormin), Celiprolol (Selectol )
1 25 mg 50 mg qdSelectol 200-400mg
: , , 2 3
-adrenaline Angiotensin II Aldosterone 1 : 5-20%
captopril (): 25 mg bid-tidenalapril (): 10-40 mg/day 1-2
lisinopril (): 20-40mg qdfosinopril (): 20mg qd
Angiotensin II : losartan, irbesartan, valsartan Angiotensin II
AT1 ACEi , but Angiotensin II losartan (): 50mg qdvalsartan ():
80mg qdtelmisartan (): 40mg-80mg qdirbesartan (): 150mg
qdOlmesartan(): 10mg-40mg qd*thiazide : .. , .. Angiotensin II :
amlodipine, nifedipine, verapamil Ca2+ , , , , , Felodipine
(Munobal), Amlodipine (Novasc )1) 5mg 1 1 10mg 2) - ,, , 3) - , , ,
, ,
diltiazem (), verapamil ()
nifedipine (): 30-60mg qd
