Integgyrated Electronic Systems and Biomedical … 2011...Integreeritud elektroonikasüsteemide ja biomeditsiinitehnika tippkeskus Department of Computer Engineering ati.ttu.ee Centre

Integreeritud elektroonikasüsteemide ja biomeditsiinitehnika tippkeskus

Department of Computer Engineeringati.ttu.ee

Centre for research excellence

Integrated Electronic Systems and g yBiomedical Engineering – CEBE

(2008 2011 2015)(2008-2011-2015)

Kolm aastat otsinguid, tegusid, tulemusi

Mart MinThomas Johann Seebeck Department of Electronics

Tallinn University of TechnologyDepartment of Computer Engineering04. oktoober 2011

Integreeritud elektroonikasüsteemide ja biomeditsiinitehnika tippkeskus© Raimund Ubar

How the research and industrial development are organised in our field of activities?

Pro d u ct D eve lo p m en t

In d u s try B u s in e s s

B a s ic R e s e a rc h C en tre fo r re se arc h

C

A p p lie d an d In d u s try R e s e a rc h

C o m p e te n c e C e n tre E x p o rt E le c tro n ic /ele c tric a l m e d ic a l/b io te c h a n d s o ftw a re p ro d u c ts

e xc elle nc e C E B E E m b e d d e d

e le c tro n ic s a n d

C o m p e te n c e C e n tre T A K E L IK O

E le c tro n ic s & IC T

pb io m e d ic a l e n g in .

G o ver nm en ta l a nd P ub lic S e c to r E U d E t iE U a n d E s to n ia


O iOverview

What is CEBE (structure, mission, research fields)

Cooperation projects (internal and external) IAB suggestions and CEBE responses IAB suggestions and CEBE responses Formal results

(PhD theses patents publications dissemination finances)(PhD theses, patents, publications, dissemination, finances)

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Wh ?Who are we?

Research groups ( ihtfi t d ük d) Research groups (sihtfin teemad, üksused):

Design of dependable embedded systems (R.Ubar) Department of Computer EngineeringDepartment of Computer Engineering

Electronic components and subsystems of mission critical embedded systems(M.Min)c ca e edded sys e s( )Th.J. Seebeck Department of Electronics

Interpretation of biosignals in medical engineering (I.Fridolin) Technomedicum – biomedical engineering

St ff Staff: Researchers/professors – 70-80 PhD students 56 PhD students – 56

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O i iOur mission

Improvement of the quality life through technological innovation by the aid of

interdisciplinary research in: electronics and signal processing; analog and digital design, testing, diagnostics; engineering in biology and medicine

with applications in the field of mission critical and dependable

b dd d t i t d d tl (b l )embedded systems, intended mostly (but not only) for advancing medical-, food- and biotechnology

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Embedded Systems

Traditional Our focus is:

Embedded SystemsContain Application Specific Computers/Processors

Traditional computers medicine

&i iengineering

inbiotechbi l

Microprocessor market shares

98 % biologyfood tech

etc 2 %

98 %

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Our resultful focusesOur resultful focusesImpedance

Investigation of brain signals p

spectroscopyDepression

analysis based on

(EEG)

Cardiacmonitors

Interpretation of

analysis, based on EEG info

monitors, stimulators

Optical analysis

for

Biosignals Qualities of blood vessels

Signal processing

Design of Verification, test and diagnostics

fordialysis

Signal processing algorithms

gEmbedded Systems

gin electronics

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Internal cooperation projects

O ti l l i

Internal cooperation projects

Optical analysis for dialysis

P5: TM/ATI

Design Platform for Embedded Systems

Noninvasive methods of cardiology

Embedded System Verification

P1: ELIN/ATIP3: TM/ELIN P2: ATI/ELIN

El i B dEEG signal analyzer

P4: TM/ATI

Electronic Board Testing

P6: ATI/ELIN/TM

Applications in MedicinNew Ideas


S l t d R ltSelected Results A method for determining depressive disorders by measuring A method for determining depressive disorders by measuring

and analyzing of brain EEG signals (SASI algorithm) was invented and implemented as a mobile deviceN l ti l th d f ti ti th ffi i f di l i Novel optical method for estimating the efficiency of dialysis:surprising synergy was achieved bringing the ideas from the diagnostics of electronics into medical diagnosing

Original methods of signal generation and processing for broad-band impedance spectroscopy were invented and implemented in medicine and engineeringg g

A platform for automated design of specialized signal processors New verification methods for embedded systems including an

t l f t f lt i l t ith d b t 5 10 ti extremely fast fault simulator with a speed-up about 5-10 times compared to the existing professional tools

A system for automated test synthesis for electronic boards,

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y y ,today the test programs for boards are written manually


How we work with 6 internal CEBE projectsHow we work with 6 internal CEBE projects

Algorithm[MatLab]

Signal source[ l ]

Platform[f k] [analog][framework]

Design space exploration[different architectures]:

to industrial development

Prototype

Is it allowed to make prototypesIs it allowed to make prototypesin frames of CEBE?


I t ti l j tInternational projects20082008 Intelligent Battery Management (in wearable devices) iBatMan

with National Semiconductor Corporation, USA (2008-2011)

2009 FP7 REGPOT: Centre of Research Excellence in Dependable

Embedded Systems CREDES (2009 2012) Pa tne s Ge man Embedded Systems - CREDES (2009-2012) Partners: Germany (3), UK, Italy, Portugal

EU TEMPUS project : Curricula Reformation and Harmonization i Bi di l E i i (2009 2012)in Biomedical Engineering (2009-2012)

2010FP7 STREP: DIAMOND Diagnosis Error Modeling and Correction FP7 STREP: DIAMOND - Diagnosis, Error Modeling and Correction for Reliable Systems Design, Coordinator: TU Tallinn (2010-2013)Partners: IBM, Ericsson, Germany, Sweden, Austria, Hungary

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N i t ti l j t

2011

New international projects

2011

FP7-SME: SafeMetal (2011-2013). Increasing EU citizen security by utilizing innovative intelligent signal processing systems for Euro-coin validation and metal quality testing.Partners: Estonia (3, incl. coordinator), Latvia, UK, Slovakia, Greece, Cyprus

EUROSTARS: COMBOARD (2011-2013). FPGA-Based Test ( )Acceleration Methodology for Complex Electronic Boards project (leader is Testonica OÜ). Partners: Germany (2), Estonia (2)

International DAAD PhD Network (2011-2014). Partners: Universities from Germany, Poland, Slovak Republic, Estonia (TTU)

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CEBE I t ti l Ad i B d (IAB)CEBE International Advisory Board (IAB)

B hi M Al H hi i U i i f S h UK Bashir M. Al-Hashimi - University of Southampton, UK(electronics, energy harvesting)

Jürgen Bommer - Dialysezentrum Heidelberg, Germany Jürgen Bommer Dialysezentrum Heidelberg, Germany(medicine)

Bernard Courtois – CMP (Grenoble) France (micro-nano electronics) Rainer Dorsch - IBM, Germany (digital systems, computers) Manfred Glesner - TU Darmstadt, Germany (electronic design) Ahmed Jerraya - CEA-LETI, MINATEC, France (bio-nano, MEMS) Jaakko Malmivuo - Tampere UT, Finland (biomed engineering) Uwe Pliquett Institut für Bioprozess und Uwe Pliquett - Institut für Bioprozess- und

AnalysenMesstechnik, Germany (biotech, measurement science) Marta Rencz - Budapest University of Technology, Hungaryp y gy, g y

(electronics)14


CEBE I t ti l Ad i B d IABCEBE International Advisory Board - IAB IAB Conferences IAB Conferences

April, 2009 – presentations, discussions, recommendations. September, 2010 – presentations of CEBE, discussions, September, 2010 presentations of CEBE, discussions,

statments of the IAB members about the results and organisation of CEBE.

R i Reporting CEBE full report about 2-year activities on 37 pages.

IAB f db k CEBE lt d ti 6 IAB feedback on CEBE results and suggestions on 6 pages.In fact, the IAB suggested to establish a new and modern

International Faculty at the University, including reasearch, International Faculty at the University, including reasearch, teaching on the MSc and PhD levels, also engineering and development for the industry, economy and society, both in Estonia and EUEstonia and EU.

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IAB M f SIAB: Measures of Success

S ti f IABSuggestions of IAB Definition of some project demonstrators would make the

l ti i d ld id d progress evaluation easier and would provide good marketing opportunities for the Centre itself.

Going towards demonstrators (CEBE internal projects): Project P1: Task driven signal processor architectures

f b dfor bioimpedance spectroscopy; Project P4: Electronic implementation of the algorithms for

detection of mental disorders as a specific signal processor;detection of mental disorders as a specific signal processor; Project P5: Analyzer for dialysis.

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PhD theses, patents, publications, presentations (2008-2010)

PhD theses – 13PhD theses 13 Patent applications – 15 Patents - 6 Patents - 6 Publications:

Journal papers 84 (ISI WoS 57 other 27)• Journal papers – 84 (ISI WoS – 57, other - 27)• Full texts of conference presentations – 130• Monographies – 6• Monographies 6

Public presentations and other eventsYear Radio TV Articles Seminars/WS Presentations/LecturesYear Radio TV Articles Seminars/WS Presentations/Lectures2008 1 5 2 22009 7 3 9 2 82010 8 1 4 1 1

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CEBE fiCEBE finances Planned direct financing 2008 - 2015:g

EU Structural Funds – 4,2 million € (77,38 milj. EEK) State budget support – 0,27 million € (4,22 milj. EEK)

2010 total budget of CEBE: Planned CEBE financing - 583 k€ (24%) Different EU projects - 600 k€ (25%) Target financing - 636 k€ (27%) Industry and other sources - 148 k€ ( 6 %)

f i 20 k€ ( 8%) Infrastructure investments - 420 k€ (18%)-------------------------------------------------Kokku: 2387 tuh €Kokku: 2387 tuh.€

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Integgyrated Electronic Systems and Biomedical … 2011...Integreeritud elektroonikasüsteemide ja biomeditsiinitehnika tippkeskus Department of Computer Engineering ati.ttu.ee Centre