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ヒルトン成⽥ H I L T O N N A R I T A 千葉成⽥市⼩菅4 5 6 2 8 6 - 0 1 2 7 456 Kosuge Narita CHIBA 286-0127 JAPAN NVND-2018 International Conference on Neurovascular and Neurodegenerative Diseases October 15-17 2018

International Conference on NVND-2018 Neurovascular and ... · Alzheimer’s Disease Ogan Gurel, Daegu Gyeongbuk Institute of Science & Technology, South Korea 14:20 Parkinson’s

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Page 1: International Conference on NVND-2018 Neurovascular and ... · Alzheimer’s Disease Ogan Gurel, Daegu Gyeongbuk Institute of Science & Technology, South Korea 14:20 Parkinson’s

ヒルトン成⽥

H I L T O N N A R I T A千葉県成⽥市⼩菅4 5 6 2 8 6 - 0 1 2 7456 Kosuge Narita CHIBA 286-0127 JAPAN

NVND-2018International Conference on

NeurovascularandNeurodegenerativeDiseases

October 15-172018

Page 2: International Conference on NVND-2018 Neurovascular and ... · Alzheimer’s Disease Ogan Gurel, Daegu Gyeongbuk Institute of Science & Technology, South Korea 14:20 Parkinson’s

Venue Floor Plan

Page 3: International Conference on NVND-2018 Neurovascular and ... · Alzheimer’s Disease Ogan Gurel, Daegu Gyeongbuk Institute of Science & Technology, South Korea 14:20 Parkinson’s

Day-1Program

07:30 Registrations and Introduction to NVND-2018 @ Foyer Area

Keynote Session @ Royal Hall 3

08:30 New Approaches in Neurological Diseases: From the Digital to the Electronic Ogan Gurel, Daegu Gyeongbuk Institute of Science & Technology, South Korea

09:10 The Green Tea Amino Acid Theanine Accelerates Neurogenesis from Neural Progenitors

Yukio Yoneda, Kanazawa University, Japan

09:50 Mitochondrial Dysfunction in the Mechanism of Neurodegeneration of Familial Form of Parkinson’s Disease

Andrey Y Abramov, UCL Institute of Neurology, UK

10:30 Coffee Break @ Foyer Area

Session 1 @ Royal Hall 3

Diagnostics of Neurodegenerative Diseases: Neuroimaging, Biomarkers and Laboratory Studies

Neurodegenerative Diseases: Prevention, Treatment and Therapeutic Options

Chairs: Yukio Yoneda, Kanazawa University, Japan | Michael J Brenner, University of Michigan, USA

10:45 What if Parkinson’s Disease Symptoms are Cortical? Gordon W Arbuthnott, OIST Graduate University, Japan Marianela Garcia Munoz, OIST Graduate University, Japan

11:05 Incidence, Risk Factors and Genetic Associations of Leukoaraiosis Indicate Pathophysiological Mechanisms in White Matter Lesions Etiology

Chi-Meng Tzeng, Jiansu Institute of Translational Medicine and Translation Medicine Research Center Xiamen University, China

11:25 Endothelial TIGAR Protects Tight Junction Integrity and the Blood Brain Barrier From Excessive Autophagy During Hypoglycemic Stress

Feng Han, Nanjing Medical University, China

11:45 Progressive Neuropathy – Does the Bladder Matter in Multiple Sclerosis (MS)? Gurpreet Singh, NHS, UK

12:05 Role of Green Tea Catechin Metabolites on the Brain: A Study of the Blood-Brain Barrier Permeability and the Neuritogenic Activity

Keiko Unno, University of Shizuoka, Japan

12:25 Terahertz Spectroscopic Diagnosis of Myelin Deficit Brain with Chemometrics Yi Zou, Institute of Fluid Physics, China

12:45 Neurovascular Coupling in the Striatum under Normal and Diseased Condition Yen-Yu Ian Shih, University of North Carolina, USA

13:05 Lunch @ Crown Room

MONDAY, OCTOBER 15, 2018

NVND-2018 MEETING GUIDE 3

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14:00 Terahertz Imaging and Electromagnetic Model of Axon Demyelination in Alzheimer’s Disease

Ogan Gurel, Daegu Gyeongbuk Institute of Science & Technology, South Korea

14:20 Parkinson’s Disease in Japan Yuko Harada, Yamato Tokushukai Hospital, Japan

14:40 Neurovascular Manifestations of Oxidative Stress in Diabetes, Smoking, and Surgical Wound Healing

Michael J Brenner, University of Michigan, USA

15:00 Can Valproic Acid Treat Neurodegenerative Diseases? Atsuko Kimura, Tokyo Metropolitan Institute of Medical Science, Japan

15:20 Autoimmune Biomarkers and AI Algorithms Could Lead to New Diagnosis and Treatment Options in Neurodegenerative Diseases Such as Glaucoma

Franz Grus, University Medical Center, Germany

15:40 Networking Break @ Foyer Area

Session 2 @ Royal Hall 3 Advances in Stroke Management | Stroke: Prevention, Treatment and Recovery

Chair: Alberto Friedmann, Indiana State University, USA

15:55 Stroke Cerebroprotection: Role of Endogenous Progesterone and its Intaracellular Receptors Rachida Guennoun, INSERM, University Paris-Sud and University Paris-Saclay, France

16:15 A Nearly Full-recovery From AVM Hemorrhagic Stroke 17 Years After Insult Using a New Integrated Neurodevelopmental Approach. A Case Study

Alberto Friedmann, Indiana State University, USA

16:35 Dual-afferent Sensory Input Training for Voluntary Movement After Stroke: A Pilot Randomized Controlled Study

Seahyun Bae, Dongshin University, South Korea

16:55 Longitudinal Measurement of Blood-brain Barrier Permeability and Cerebrospinal Fluid Level of Matrix Metalloproteinases in Rhesus Monkeys Subjected to Transient Ischemic Stroke

Zhihui Zhong, Sichuan University, China

17:15 Patients with the History of Stroke: Drug Treatment and Outcomes in Real Outpatient Practice

Mikhail Loukianov, National Medical Center for Preventive Medicine, Russia

17:35 Neural Activity-dependent Transcription Factor Npas4 Plays a Crucial Role in Neuronal Survival After Ischemic Stroke

Akio Tsuboi, Osaka University, Japan

Day-1Program MONDAY, OCTOBER 15, 2018

4 NVND-2018 MEETING GUIDE

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Keynote Session @ Royal Hall 3

08:00 Neuropathology and Diagnosis of Dementia: Novel Approach Rajendra Badgaiyan, Icahn School of Medicine at Mt. Sinai, USA

08:40 Structural and Functional MRI Correlates of Poststroke Depression Wai Kwong Tang, Chinese University of Hong Kong, China & CUHK Shenzhen Research

Institute, China

Symposium on: “Novel Therapeutic Targets for Neurodegeneration”

Chair: Katsura Takano, Osaka Prefecture University, Japan

09:20 The Role of Prostaglandin E2 in Dopaminergic Neurodegeneration of Parkinson’s Disease

Yuri Ikeda-Matsuo, Hokuriku University, Japan

09:40 Transglutaminases in Neurodegenerative Diseases Katsura Takano, Osaka Prefecture University, Japan

10:00 Protective Role of NDRG2 in Blood-brain Barrier Integrity Following Ischemia Mika Takarada-Iemata, Kanazawa University, Japan

10:20 Challenge to Elucidate the Cause of Depression-like Symptoms by Individuality Hirotaka Oikawa, Suzuka University of Medical Science, Japan

10:40 Coffee Break @ Foyer Area

Session 3 @ Royal Hall 3 Alzheimer’s Disease, Dementia and Mild Cognitive Impairment Translational Insights and Therapeutic Opportunities

Chair: Rajendra Badgaiyan, Icahn School of Medicine at Mt. Sinai, USA

10:55 Is Isorhynchophylline a Promising Agent for Alzheimer’s Disease: Pharmaco-logical Studies on TgCRND8 Transgenic Mice

Zhi-Xiu Lin, The Chinese University of Hong Kong, Hong Kong

11:15 Magnolol, Honokiol and their Combination Ameliorate the Cognitive Deficits Induced by Beta Amyloid1-42 in Rats via GSK-3β Signaling Pathway

Yan-Fang Xian, The Chinese University of Hong Kong, Hong Kong

11:35 Neuronal Signaling Imbalances Underlie Early Sensory Deficit in Dementia Lavinia Alberi, Swiss Integrative Center for Human Health, Switzerland

11:55 Cholinergic Grb2-Associated-Binding Protein 1 Regulates Cognitive Function through SK Channel

Ying-Mei Lu, Zhejiang University, China

TUESDAY, OCTOBER 16, 2018Day-2Program

NVND-2018 MEETING GUIDE 5

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12:15 Disease Management in Alzheimer’s Disease Centre: The Analysis of Dementia Cases Followed Up from Diagnosis to Death

Nataliya Mikhaylova, IFSBSI “Mental Health Research Center”, Russia

12:35 Automated Operand Conditioning as a Reproducible Cognitive Challenge to Study Treatment Effects in Pig Models

Christian Manteuffel, Leibniz Institute for Farm Animal Biology, Germany

12:55 Therapeutic Potential of Targeting NLRP3 Inflammasome for Alzheimer’s Disease Dong Sun, Virginia Commonwealth University, USA

13:15 Lunch @ Crown Room

14:05 Activated Forms of Astrocytes with Higher GLT-1 Expression are Associated with Cognitive Normal Subjects with Alzheimer Pathology in Human Brain

Eiji Kobayashi, Sapporo Medical University, Japan

14:25 Should the Treatment of Amyloidosis be Personified? Molecular Mechanism of Amyloid Formation by Abeta Peptide and its Fragments

Oxana V Galzitskaya, Institute of Protein Research, Russia

14:45 Determination of Regions Involved in Amyloid Fibril Formation: Abeta Peptide and its Fragments

Alexey Surin, Institute of Protein Research, Russia

15:05 Predictive Factors for Dementia and Cognitive Impairment Among Residents Living in the Veterans’ Retirement Communities in Taiwan: Implications for Cognitive Health Promotion Activities

Liang-Yu Chen, Taipei Veterans General Hospital, Taiwan

15:25 Molecular Hydrogen Inhalation Treatment for Neurovascular and Neuro-degenerative Disease

Hirohisa Ono, Juntendo University, Japan

15:45 Sphingosine 1-Phosphate Metabolism in Alzheimer’s Disease Olivier Cuvillier, INSERM, France

16:05 Multisession Cyberknife Radiosurgery for Large AVM and AVM in Eloquent Regions Shinichiro Miyazaki, Shin-yurigaoka General Hospital, Japan

16:25 Integration of Gene Expression and GWAS Results Supports Involvement of Calcium Signaling in Schizophrenia

Libi Hertzberg, Shalvata Mental Health Center, Israel

16:45 Coffee Break @ Foyer Area

17:00 Poster Presentations @ Foyer Area

Day-2Program TUESDAY, OCTOBER 16, 2018

6 NVND-2018 MEETING GUIDE

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NVND-01 Social Participation Related to Cognitive Performance in Community-dwelling Older Adults: A Prospective Cohort Study in Japan

Kimiko Tomioka, Nara Prefectural Health Research Center, Japan

NVND-02 Analysis of Micro and Macrolinguistic Aspects in the Narratives of Individuals with Alzheimer’s Disease, Mild Cognitive Impairment and No Cognitive Impairment

Cintia Toledo, University of São Paulo, Brazil

NVND-03 Effect of Erinacine A-enriched Hericium erinaceus on Anti-aging in Senescence Accelerated Mice

Liya Lee, Grape King Bio Ltd., Taiwan

NVND-04 Effect of Erinacine A-enriched Hericium erinaceus on Learning and Memory in Senescence Accelerated Mice

I-Chen Li, Grape King Bio Ltd., Taiwan

NVND-05 An Adult Case of Noonan Syndrome Associated with Persistent Right Primitive Olfactory Artery and Vertebrobasilar Artery Hypoplasia

Yasushi Shibata, University of Tsukuba, Japan

NVND-06 Neuronal Defects in TAF15-Expressing Flies are Suppressed by Parkin Kiyoung Kim, Soonchunhyang University, South Korea

NVND-07 Predictors of Subclinical Multifocal Atherosclerosis and it’s Relationship with the Metabolic Syndrome

Tatyana Naiden, State North-Western University by I.I. Mechnikova, Russia

NVND-08 Plasma Protein Profiling for Potential Biomarkers in the Early Diagnosis of Alzheimer’s Disease

Yuki Kitamura, Kinjo Gakuin University of Pharmacy, Japan

NVND-09 Emergency Microsurgical Embolectomy in Acute Ischemic Stroke with Diffusion-Negative MRI

Sung Don Kang, Wonkwang University Hospital, South Korea

NVND-10 MicroRNA´s are New Generation Markers of Alzheimer’s Disease David Stejskal, University Hospital Ostrava, Czech Republic

NVND-11 Pharmacological Actions of Hydrogen Sulfide Donors on Sympathetic Neurotransmission in the Bovine Anterior Uvea, In vitro

Catherine A Opere, Creighton University, USA

NVND-12 Frequency of RNF213 p.R4810K Variant in Korean Patients Undergoing Trans-femoral Cerebral Angiography for Stent Insertion

Eunsin Bae, Veterans Health Service Medical Center, South Korea

Poster PresentationsDay-2Program

NVND-2018 MEETING GUIDE 7

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NVND-13 The Pyk2/MCU Pathway in the Rat Middle Cerebral Artery Occlusion Model of Ischemic Stroke

Kun Zhang, Hebei Medical University, China

NVND-14 Inhibition of Okadaic acid-induced Tau Hyperphosphorylation by Dendrobium nobile

So-Young Park, Dankook University, South Korea

NVND-15 Functional Characterization of Supt4h using GABAergic Neuron Cells Derived From iPSCs of Huntington’s Disease Patients

Yu-Shiuan Lin, Academia Sinica, Taiwan

NVND-16 Scrapie-associated Polymorphisms of Prion Protein Gene (PRNP) in Korean Native Black Goats

Seonkwan Kim, Chonbuk National University/Korea Zoonosis Research Institute, South Korea

NVND-17 A Double-blind Randomized Control Trial of Vagus Nerve Stimulation for Pediatric Patients with Drug Refractory Epilepsy

Zhao Yang, Tsinghua University, China

Poster PresentationsDay-2Program

8 NVND-2018 MEETING GUIDE

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Session 4 @ Royal Hall 3 Parkinson’s Disease and other Movement Disorders

Chair: Yuko Harada, Yamato Tokushukai Hospital, Japan

09:00 Comparison of Body Composition, Nutritional Habits, and Components in Parkinson´s Disease Patients Living in Urban and Country Side Environmental

Arthur Oscar Schelp, São Paulo State University, Brazil

09:20 Gait Assessment using Non-Motorized Treadmill in Patients with Parkinson Disease and Non-Disabled Individuals

Chia-Yu Kuo, Taipei Veterans General Hospital, Taiwan

09:40 RNA-Sequencing of Parkinson’s Disease Brain Tissues Indicates LRRK2-Mediated Protection by the Long Non-coding RNA NEAT1

Alon Simchovitz, Hebrew University of Jerusalem, Israel

10:00 Increased Expression of AQP4 and AQP9 in Hippocampus of Eclampsia-like Rat Model

Huang Qian, Guangzhou Medical University, China

10:20 Coffee Break @ Foyer Area

12:00 Lunch & Departures @ Crown Room

WEDNESDAY, OCTOBER 17, 2018Day-3Program

NVND-2018 MEETING GUIDE 9

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