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Mendelian genetics. Gregor Mendel. Father of modern genetics Researched with pea plants. Gregor Mendel. Father of modern genetics Researched with pea plants Developed ideas of dominance and trait segregation. Beberapa Istilah Yang sering digunakan. - PowerPoint PPT Presentation
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Mendelian genetics
Gregor Mendel
• Father of modern genetics
• Researched with pea plants
•
Gregor Mendel
• Father of modern genetics
• Researched with pea plants
• Developed ideas of dominance and trait segregation
Beberapa Istilah Yang sering digunakan
• parental (P) : induk/ orang tua (parents)• filial (F) : keturunan (misal F1 adalah keturunan
pertama, F2 keturunan kedua)• fenotip : karakter individu yang dapat diamati, misal
bentuk, warna, dan ukuran• genotip : susunan genetik suatu individu (gabungan
gen), biasanya ditulis dengan simbol huruf dobel, misalnya AA, BB, cc, dd dan seterusnya
• alel : pasangan gen (misal, gen M menentukan warna merah, dan alelnya m menentukan warna putih). M alel dominan, m alel resesif
Beberapa Istilah Yang sering digunakan
• Homozigot : sifat suatu individu yang genotipnya terdiri dari alel-alel yang sama untuk tiap jenis gen. Contoh : RR, rr, AABB, aabb dan lain-lain
• Heterozigot : sifat suatu individu yang genotipnya terdiri dari alel-alel yang berlainan dari tiap jenis gen. Contoh : Rr, AaBb dan lain-lain
• Hibrid : perkawinan antara dua individu yang memiliki sifat beda (monohibrid : satu sifat beda, dihibrid : dua sifat beda)
• Persilangan resiprok : persilangan yang merupakan kebalikan dari persilangan semula
• Persilangan kembali (backcross) : persilangan antara hibrid F1 dengan induknya jantan atau betina
• Uji Silang (testcross) : persilangan antara hibrid F1 dengan individu yang homozigot resesif
Phenotype
• Phenotype – Physical
characteristics
Genotype
• Phenotype – Physical
characteristics
• Genotype – Genes we inherit
from our parents
Phenotype
– Facial structure
Notice the similarities:
Phenotype
– Facial structure– Eyes
Notice the similarities:
Phenotype
– Facial structure– Eyes– Smile
Notice the similarities:
Phenotype
– Facial structure– Eyes– Smile– Ears
Notice the similarities:
Phenotype
– Facial structure– Eyes– Smile– Ears– Nose
Notice the similarities:
Phenotype
– Facial structure– Eyes– Smile– Ears– Nose– Neck
Notice the similarities:
Mendelian Genetics
Mendel studied a number of characteristics in pea plants including:
• Height - short or TALL
Mendelian GeneticsMendel studied a number of characteristics in pea plants including:
• Height - short or TALL• Seed color - green or YELLOW
Mendelian Genetics
Mendel studied a number of characteristics in pea plants including:
• Height - short or TALL• Seed color - green or YELLOW• Seed shape - wrinkled or ROUND
Mendelian Genetics
Mendel studied a number of characteristics in pea plants including:
• Height - short or TALL• Seed color - green or YELLOW• Seed shape - wrinkled or ROUND• Seed coat color - white or GRAY
Mendelian Genetics
Mendel studied a number of characteristics in pea plants including:
• Height - short or TALL• Seed color - green or YELLOW• Seed shape - wrinkled or ROUND• Seed coat color - white or GRAY • Pod shape - constricted or SMOOTH
Mendelian Genetics
Mendel studied a number of characteristics in pea plants including:
• Height - short or TALL• Seed color - green or YELLOW• Seed shape - wrinkled or ROUND• Seed coat color - white or GRAY • Pod shape - constricted or SMOOTH• Pod color - yellow or GREEN
Mendelian Genetics
Mendel studied a number of characteristics in pea plants including:
• Height - short or TALL• Seed color - green or YELLOW• Seed shape - wrinkled or ROUND• Seed coat color - white or GRAY • Pod shape - constricted or SMOOTH• Pod color - yellow or GREEN• Flower position - terminal or AXIAL
Mendelian Genetics
We will work with the following three:
• Height - short or TALL• Seed color - green or YELLOW• Seed shape - wrinkled or ROUND• Seed coat color - white or GRAY • Pod shape - constricted or SMOOTH• Pod color - yellow or GREEN• Flower position - terminal or AXIAL
Mengapa penelitian Mendel menggunakan kacang Ercis?
• berumur pendek, mudah tumbuh dan mudah disilangkan
• memiliki bunga sempurna (memiliki benang sari dan putik)
• dapat melakukan penyerbukan sendiri dan dapat disilangkan dengan bantuan manusia
• memiliki variasi karakter (7) dengan perbedaan yang menyolok (batang, warna polong, tekstur polong, warna bunga, letak bunga, warna biji, dan permukaan biji).
Persilangan yang dilakukan Mendel pada kacang kapri
Predicting Inheritance
To determine the chances of inheriting a given trait, scientists use Punnett squares and symbols to represent the genes.
UPPERCASE letters are used to represent dominant genes.
lowercase letters are used to represent recessive genes.
Predicting Inheritance
For example:T = represents the gene for TALL in pea plantst = represents the gene for short in pea plants
So:TT & Tt both result in a TALL plant, because T is dominant over t. t is recessive. tt will result in a short plant.
Remember there are two genes for every trait! One from each parent.
Predicting Inheritance
For example:T = represents the gene for TALL in pea plantst = represents the gene for short in pea plants
So:TT & Tt both result in a TALL plant, because T is dominant over t. t is recessive. tt will result in a short plant.
Remember there are two genes for every trait!
Mendels’ Principle of Dominance
Some genes (alleles) are dominant and others are recessive. The phenotype (trait) of a dominant gene will be seen when it is paired with a recessive gene.
Predicting Inheritance
Let’s cross a totally dominant tall plant (TT) with a short plant (tt).Each plant will give only one of its’ two genes to the offspring or F1 generation.
TT x tt
T T t t
Predicting Inheritance
Let’s cross a totally dominant tall plant (TT) with a short plant (tt).Each plant will give only one of its’ two genes to the offspring or F1 generation.
TT x tt
T T t t
Mendels’ “Law” of Segregation
Each gene (allele) separates from the other so that the offspring get only one gene from each parent for a given trait.
Punnett Squares
Tt Tt
Tt Tt
The genes from one parent go here.
The genes from the other parent go here.
Punnett Squares
T T
t Tt Tt
t Tt Tt
Punnett Squares
T T
t Tt Tt
t Tt Tt
Punnett Squares
T T
t Tt Tt
t Tt Tt
Punnett Squares
T T
t Tt Tt
t Tt Tt
Punnett Squares
T T
t Tt Tt
t Tt Tt
Punnett Squares
T T
t Tt Tt
t Tt TtF1 generation
Interpreting the ResultsThe genotype for all the offspring is Tt.The genotype ratio is:
Tt - 4/4
The phenotype for all the offspring is tall.The phenotype ratio is:
tall - 4/4
Punnett Squares
T t
T ?? ??
t ?? ??
Your Turn!!
Punnett Squares
T t
T TT Tt
t Tt ttF2 generation
Punnett Squares
T t
T TT Tt
t Tt tt
Next, give the genotype and phenotype ratios of the offspring (F2 generation).
Punnett Squares
T t
T TT Tt
t Tt tt
Genotype ratio: TT - 1
Punnett Squares
T t
T TT Tt
t Tt tt
Genotype ratio: TT - 1, Tt - 2
Punnett Squares
T t
T TT Tt
t Tt tt
Genotype ratio: TT - 1, Tt - 2, tt - 1
Punnett Squares
T t
T TT Tt
t Tt tt
Genotype ratio: TT - 1, Tt - 2, tt - 1
Phenotype ratio: Tall - 3
Punnett Squares
T t
T TT Tt
t Tt tt
Genotype ratio: TT - 1, Tt - 2, tt - 1
Phenotype ratio: Tall - 3, short - 1
Punnett Squares
T t
T TT Tt
t Tt tt
This is a monohybrid cross. We worked with only one trait. The height of the plant.
Punnett Squares
T t
T TT Tt
t Tt tt
This is a monohybrid cross. We worked with only one trait. The height of the plant.
Later we will work with a dihybrid cross, using the height of the plant and either seed color or seed shape.
two
