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Ras-raf- MEK AKT PI3K PTEN mTOR TSC 2 TSC 1 LKB1 AMPK TORC1 TORC2 mTOR mTORC1/2 inhibitors Tyrosine kinase inhibitors AKT inhibitors Metformine Rapalogs: Everolimus Temsirolimus ridaforolimus PI3K inhibitors PI3K dependent pathway AMPK-dependent PI3K independent pathway ENERGY PATHWAY

Ras-raf- MEK

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AMPK-dependent PI3K independent pathway ENERGY PATHWAY. Tyrosine kinase inhibitors. PI3K dependent pathway. Ras-raf- MEK. AKT inhibitors. LKB1. PI3K inhibitors. PI3K. PTEN. AMPK. AKT. TORC2. mTOR. Metformine. TSC2. TSC1. mTORC1/2 inhibitors. TORC1. mTOR. Rapalogs : - PowerPoint PPT Presentation

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Page 1: Ras-raf- MEK

Ras-raf-MEK

AKT

PI3K

PTEN

mTOR

TSC2 TSC1

LKB1

AMPK

TORC1

TORC2mTOR

mTORC1/2 inhibitors

Tyrosine kinase inhibitors

AKT inhibitors

Metformine

Rapalogs:Everolimus

Temsirolimusridaforolimus

PI3K inhibitors

PI3K dependent pathway

AMPK-dependentPI3K independent pathway

ENERGY PATHWAY