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The value of echocardiography in stroke management Asjid Qureshi, Specialist registrar to Dr S Nussey

The value of echocardiography in stroke management Asjid Qureshi, Specialist registrar to Dr S Nussey

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Page 1: The value of echocardiography in stroke management Asjid Qureshi, Specialist registrar to Dr S Nussey

The value of echocardiography in stroke management

Asjid Qureshi,

Specialist registrar to Dr S Nussey

Page 2: The value of echocardiography in stroke management Asjid Qureshi, Specialist registrar to Dr S Nussey

Echocardiography at St George’s Hospital

• Each echocardiogram is estimated to cost £55 • 12,000 requests are received per year• Total cost of £660,000• 30-35 echocardiograms performed per day• Average outpatient wait for routine echo is 6

weeks• Only “urgent” inpatient echos are done during

admission

Page 3: The value of echocardiography in stroke management Asjid Qureshi, Specialist registrar to Dr S Nussey

Echocardiography in stroke management at St George’s Hospital

• Already a filtering system in place

• Only those with a cardiac history (AF, previous

MI, murmur) are accepted

• Those requests without this are filtered out, unless

you persist!

Page 4: The value of echocardiography in stroke management Asjid Qureshi, Specialist registrar to Dr S Nussey

To estimate the frequency of management altering abnormal echocardiograms in stroke patients at St

George’s Hospital

Aim of this audit

Page 5: The value of echocardiography in stroke management Asjid Qureshi, Specialist registrar to Dr S Nussey

Methods

• All admissions to Thomas Young Ward

• Between 1-1-01 and 1-6-01

• Details from ward register

• Search for echocardiogram results on all

• Review appropriate notes

Page 6: The value of echocardiography in stroke management Asjid Qureshi, Specialist registrar to Dr S Nussey

Patient details from ward register

Abnormal echocardiogram report?

No

Management altering abnormality?

Yes

NoYes

Did it alter management?

Echocardiogram result from cardiology database

Page 7: The value of echocardiography in stroke management Asjid Qureshi, Specialist registrar to Dr S Nussey

Thomas Young ward register

• Name• Hospital number• DOB• Date of admission/discharge• Consultant• Diagnosis• Follow up arrangements

Page 8: The value of echocardiography in stroke management Asjid Qureshi, Specialist registrar to Dr S Nussey

Echocardiogram search

• On the hospital number

• Name and/or DOB

Page 9: The value of echocardiography in stroke management Asjid Qureshi, Specialist registrar to Dr S Nussey

Results

Page 10: The value of echocardiography in stroke management Asjid Qureshi, Specialist registrar to Dr S Nussey

Admissions

Number

Total 103

Male 56

Female 47

Mean no. admissions per month 20

Mean age 72yrs

Age range 35-98yrs

Page 11: The value of echocardiography in stroke management Asjid Qureshi, Specialist registrar to Dr S Nussey

Echocardiogram

Echocardiogram No echocardiogram

Total 24(23.3%) 79(76.7%)

Male 15(26.8%) 41(73.2%)

Female 9(19.1%) 38(80.9%)

Mean age 66yrs 74yrs

Age range 35-90yrs 48-98yrs

Page 12: The value of echocardiography in stroke management Asjid Qureshi, Specialist registrar to Dr S Nussey

Admissions per consultant

14

10

8

10

7

9

6

12

6

1

15

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Page 13: The value of echocardiography in stroke management Asjid Qureshi, Specialist registrar to Dr S Nussey

Echocardiograms per consultant

4 0 2 1 0 2 2 3 3 1 3

10

10

6

9

7

7

4

9

3

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No echoEcho

Page 14: The value of echocardiography in stroke management Asjid Qureshi, Specialist registrar to Dr S Nussey

Echocardiograms

Echocardiogram

Total 24

Entirely normal 10

Abnormal 14

Page 15: The value of echocardiography in stroke management Asjid Qureshi, Specialist registrar to Dr S Nussey

Echocardiogram results

10

4

2

1

3

1

11

1 Normal

Mild LV/LA dilatation

Sclerotic AV

Patent foramen Ovale

LVH

Aortic stenosis

Mildly dilated prox.Aorta

Vegetation

Moderate MR

Page 16: The value of echocardiography in stroke management Asjid Qureshi, Specialist registrar to Dr S Nussey

Value of echocardiogram

• 1 in 24 significantly positive result

• Almost 4% yield

Have I just shot myself in the foot?

Page 17: The value of echocardiography in stroke management Asjid Qureshi, Specialist registrar to Dr S Nussey

Mr DT

History49 year old AphasiaRight hemiparesisFebrileFormer IV drug user

Page 18: The value of echocardiography in stroke management Asjid Qureshi, Specialist registrar to Dr S Nussey

Mr DT

Examination

Clubbed, splinter haemorrhagesTemp 39HR 100/minBP 110/58Pan systolic murmur No splenomegaly

Diagnosis“Bacterial endocarditis and embolic CVA”

TreatmentIV cefotaxime, flucloxacillin and gentamicin

Page 19: The value of echocardiography in stroke management Asjid Qureshi, Specialist registrar to Dr S Nussey

Summary

• 103 stroke patients admitted to Thomas Young ward

• 24 had echocardiograms performed

• Far more requested though!

• 10 were entirely normal

• Only 1 had a results that would alter management

• Clinical features in that case completely supported the

request for an echocardiogram

Page 20: The value of echocardiography in stroke management Asjid Qureshi, Specialist registrar to Dr S Nussey

Low Yield of Transthoracic Echocardiography for Cardiac Source of Embolism

Vedat Sansoy et al

American Journal of Cardiology

1995;75:166-69

University of Virginia Medical Centre

Page 21: The value of echocardiography in stroke management Asjid Qureshi, Specialist registrar to Dr S Nussey

Low Yield of Transthoracic Echocardiography for Cardiac Source of Embloism

• 1,010 consecutive patients admitted with CVAs or TIAs

• 325 controls

• Exclusion criteria: MI within the prior 6weeks, orknown bacterial endocarditis

Page 22: The value of echocardiography in stroke management Asjid Qureshi, Specialist registrar to Dr S Nussey

Criteria used for determining cardiac source of embolism

Highly probable causes: Definite left ventricularDefinite left atrial thrombusDefinite left atrial myxomaDefinite valvular vegetation

Possible causes: Possible left ventricularPossible left atrial thrombusPossible valvular vegetationAtrial septal defect

Doubtful causes: Mitral valve prolapse

Mitral annular calcification

Page 23: The value of echocardiography in stroke management Asjid Qureshi, Specialist registrar to Dr S Nussey

Results

Cases (n=1010) Controls (n=325)

Male 521 [52%] 166 [51%]

Female 489 [48%] 159 [49%]

Mean age 67yrs 65yrs

Page 24: The value of echocardiography in stroke management Asjid Qureshi, Specialist registrar to Dr S Nussey

Cases (n=1010)

Number (percentage)

CVA 677 (67%)

TIA 313 (31%)

Unclear 20 (2%)

Page 25: The value of echocardiography in stroke management Asjid Qureshi, Specialist registrar to Dr S Nussey

Results

CasesControls

Definite left ventricular thrombus 2.8% 5.2%

Definite left atrial thrombus 0.0% 0.0%

Definite valvular vegetation 0.0% 2.5%

Left atrial myxoma 0.0% 0.0%

Possible left ventricular thrombus 2.0% 3.0%

Possible left atrial thrombus 0.3% 0.0%

Possible valvular vegetation 2.0% 2.0%

Atrial septal defect 0.3% 0.6%

Mitral valve prolapse 5.0% 5.0%

Mitral annular calcification 31.0% 26.0%

Page 26: The value of echocardiography in stroke management Asjid Qureshi, Specialist registrar to Dr S Nussey

Results

Cases Controls

Atrial fibrillation 14% 15%

Systemic hypertension 48% 29%

Diabetes mellitus 25% 25%

IHD 15% 33%

CCF 6% 36%

Page 27: The value of echocardiography in stroke management Asjid Qureshi, Specialist registrar to Dr S Nussey

Percentage of patients with definite, probable and doubtful cardiac source of embolus as determined by Transthoracic

two-dimensional Echocardiography after adjustment for age and various cardiovascular conditions

CasesControls

Definite cardiac source 5% 5%

Probable cardiac source 4% 4%

Doubtful cardiac source 37% 30%

Page 28: The value of echocardiography in stroke management Asjid Qureshi, Specialist registrar to Dr S Nussey

Patients anticoagulated following a positive echocardiograph result

Cases

Definite cardiac source 50%

Probable cardiac source 30%

Doubtful cardiac source 0%

The remainder were not treated with anticoagulants because of

contraindications that were known before echocardiography

Page 29: The value of echocardiography in stroke management Asjid Qureshi, Specialist registrar to Dr S Nussey

Management was altered in only 22 of 1010 patients

(2%) of whom 17 had pre-existing and known clinical

and/or electrocardiographic abnormalities

Page 30: The value of echocardiography in stroke management Asjid Qureshi, Specialist registrar to Dr S Nussey

Other findings in cases of definite or possible thrombus

Definite Possible

Q waves on ECG 54% 41%

LBBB 18% 11%

CCF 43% 26%

AF 25% 30%

Only 23% had none of these abnormalities

Page 31: The value of echocardiography in stroke management Asjid Qureshi, Specialist registrar to Dr S Nussey

Conclusion• Limited resources in echocardiogram department

• Over 25% of patients with a CVA receive an

echocardiogram at St George’s Hospital

• It is very unlikely to alter management

• Long outpatient waits for echocardiograms

• Only urgent echos performed as inpatient

• Echocardiography in CVA management is an area were

there is a need to rationalize our requests

Page 32: The value of echocardiography in stroke management Asjid Qureshi, Specialist registrar to Dr S Nussey

Take home message

• Low yield for transthoracic echocardiography in stroke management

• Most cases have other cardiological features/abnormalities

• Echocardiography is a valuable and over used resource

• We need to be far more selective in our use of echocardiography in stroke management

• Long waiting lists for routine echocardiography could be improved as a result