CEOCEO

: :

CEO CEO

: (I1000241) I

1834286346408B-I 247116I 243205I 240631I 273137

??

()

:1.2.3.4.

35(heterotroph)(autotroph)

30 -

15

http://creative.gettyimages.com/source/Search/40','40','2','http://creative.gettyimages.com/source/Search/44','44','2','

:1. :

a.b.c.

2.:a.,b.b.

35

:

(Cyanophyta)

(Chlorophyta)

(Charophyta)

(Euglenophyta)

(Chrysophyta)

(Pyrrhophyta)

(Cryptophyta)

(Phaeophyta)

(Rhodophyta)

http://www.center.kl.edu.tw/klstory/small/ch08/ch8b/89.JPG

Chlorella

Spirulina

()

GLA

Hematococcus

Astaxanthin

Crypthecodinium

DHA

Porphyridium ()

AA

http://creative.gettyimages.com/source/Search/5','5','2','

1917

1948

1951

1962

1964

1974

1976 500

1977

1985

1990

CO2

Algae Powders

Ganoderma

Microalgae MaskLotion Bath Salt

Micro-encapsulatedArtificial Plankton

Health Care

Nutriments

Flogen Probes

Multicolor probes

Anti-EV71Anti-Inf A

Anti-Herpes

Sloargen

GlobalLocalGlocal

FEBICO

Flogen

Apogen

(Chlorella) (Chlorella)

(Chlorella)

(65% l3%9 % )

Coenzyme Q9

http://images.google.com.tw/imgres?imgurl=http://www.best-of-bio.de/g/custom/product/Chlorella&imgrefurl=http://www.best-of-bio.de/chlorella---aktuelle-angebote-gro-_223e-auswahl-und-hintergrundinfos-text_204.htm&h=300&w=200&sz=13&tbnid=aB2xOLhQrfoJ:&tbnh=111&tbnw=74&hl=zh-TW&start=147&prev=/images%3Fq%3Dchlorella%2Bpicture%26start%3D140%26svnum%3D10%26hl%3Dzh-TW%26lr%3D%26sa%3DNhttp://images.google.com.tw/imgres?imgurl=http://tuberose.com/Graphics/ChlorellaCell.jpg&imgrefurl=http://tuberose.com/Chlorella.html&h=216&w=220&sz=34&tbnid=PTHPVqEZ528J:&tbnh=100&tbnw=102&hl=zh-TW&start=85&prev=/images%3Fq%3Dchlorella%2Bpicture%26start%3D80%26svnum%3D10%26hl%3Dzh-TW%26lr%3D%26sa%3DN

(PUFA)PPAR

, 2005

(C.G.F.)

Saburo Hidaka et al, 2004

10-

Guzman S et al, 2001

Merchant RE et al, 2002

Sano T et al, 1987

Health Benefits of Chlorella

(CH4)

0.5g A 830g 20.5mg

6.0g -carotene 8.61mg 80mg

0.8g Carotenoids 20mg 16.4mg

1.5g B1 0.23mg 1.5mg

0.5g B2 0.58mg 103mg

0.7g B6 0.22mg 30mg

380mg B12 10g 0.5mg

44.9mg 3.0mg 8mg

240g C 4.9mg 9gE 2.3mg 7mg

(10)

,,

(As Pb Hg Cd)

()

Lutein, -Carotene, chlorophyll

DNA DNA

4050

! 80

?

3

No.183428

-

A++

900 990

()

250cc 1680

(Lutein)

60 880

CV66

1350 1800

((SpirulinaSpirulina) )

(Spirulina) 35

0.3~0.5 mm 5~8 m100

(>90%)

0.5g A 43,000IU 17.1mg

6.7g -carotene 25.8mg 91.4mg

0.4g Carotenoids 40mg 5.3mg

125mg B1 0.48mg 177mg

1.4g B2 0.42mg 77mg

0.2g B6 0.07mg 0.4mg

0.8g B12 6.7g 70g

1.04g 150g 3.3g

150mg 150g 0mg

800mg 7mg 0.5mg

E 150g

(10)

Lisheng et al., 1991

Nayaka et al., 1988

Babu et al., 1995

Parikh et al., 2001

2.8

Becker et al., 1986

Iwata et al., 1990

B() DNA

No.94121201-02

No.1000241

FSII-OP-0010

A+

450 990

15 880

150cc153g

150cc153g

ApogenApogen

1~3612

7-10

ABC

(Hemagglutinin, HA) (Neuraminidase, NA)

A

A1 H5N1A2 H9N2

B C

Rotavirus, RV

5~10% 1050%

65 2~4

Human Respiratory syncytialvirus HRSV1956

Paramyxovirussyncytialcytopathology

1~3612

ApogenApogen

Apogen FEM-1

ApogenApogen

Tamiflu

EV71 & CA16A & B

Apogen

Apogen

Apogen Enterovirus71 (EV71) Coxsackie A16 (CA16) Influenza Virus A & B (FluA & Flu B ) Rotavirus (RV) Respiratory Syncytial Virus (RSV)

ApogenApogen EV71EV71 CA16CA16 Flu AFlu A FluBFluB RVRV RSVRSV

ICIC5050 ((g/mLg/mL)) 242242 4343

>1500>1500

383383342342

>3000>3000

4949

>2300>2300

195195

>1200>1200LCLC5050 ((g/mLg/mL)) >1500>1500

APC (Apogen)EV71

A: Vero cells only

B: EV71Vero

C: 0.238 M APC (Apogen)Vero

D: 0.238 M APC (Apogen)EV71

APC (Apogen) EV71

a: , b: ,

c ~ f : , 0.047 M 0.071 M0.119 M 0.238 M APC (Apogen)

APC (Apogen)

APC (Apogen) EV71

IC50 0.056 0.007 M 0.101 0.032 M

: APC (Apogen)

: APC (Apogen)

V

D+VAPC (Apogen)

APC (Apogen)

VP1 RNA 8APC (Apogen)RNA

APC (Apogen)

A B

C

E

D

F

A : RD B: EV71 RDCD: 0.048 M APC (Apogen) EF : 0.071 M APC (Apogen)

ApogenApogenEV71 ApogenApogen ApogenApogen ApogenApogen

ApogenApogen

ApogenApogen

ApogenApogen

ApogenApogen

ApogenApogen

ApogenApogen AB100%AApogenApogenTamiflu

ApogenApogen

Apogen

80 980

30cc 1500

Apogen

80 980

30 980

ApogenApogen

Apogen

80 980

Apogen

30 980

ApogenApogen

:

1~3%7~8%

(Green stage)

:

(Red stage)

(Astaxanthin)

- E

-10E550

http://www.dw-world.de/image/0,,1114495_4,00.jpg

(ppm)

~ 5 ppm

~ 60 ppm

~ 120 ppm

~ 1,200 ppm

~ 8,000 ppm

~ 40,000 ppm

(Haematococcus pluvialis)

http://mall.vieweaver.com/catalog/images/HA002_b.jpghttp://www.kepu.net.cn/gb/earth/antarctica/resource/images/rsr03b_pic.jpg

FDA

Fuji Chemical ( Hawaii)

(Green stage)

(Red stage)

Green stage Red stage

(Astaxanthin)

E

UV

No

10

nm100 nm 10 um

10

( 375 ) 5 (2.5)

60 980

90 980

DHA

Crypthecodinium

DHA

DHA (15%or 42%)

DHA

DHA(Docosahexaenoic acid)

-3PUFA

-3Common name Lipid name Chemical name

-Linolenic acid (ALA) 18:3 (-3) octadeca-9,12,15-trienoic acid

Eicosapentaenoic acid (EPA) 20:5 (-3) eicosa-5,8,11,14,17-pentaenoic acid

Docosahexaenoic acid (DHA) 22:6 (-3) docosa-4,7,10,13,16,19-hexaenoic acid

ALAEPADHA

DHA

DHA

,

,DHA/EPA/DPA

,,,,

DHA

DHA

DHA(PS)

DHA

2. DHA

3. DHA

1. DHA(Blood Retina Barrier)

4. DHA

5.

DHA

DHA

DHAUnit A B C

g 2.1 2.07 2.22g 5 5.49 5.49g 10.9 10.56 10.41g 134 133 133

mg 860 1000 100mg 17 8 8mg 34 22 21

DHA ARA

Nutrients per 100 Cal. Protein Fat Carbohydrates Water Linoleic Acid

Thank You for Your Attention Far East Microalgae Ind. Co., Ltd. (FEMICO)& Far East Bio-Tec Ind. Co., Ltd. (FEBICO)313A(F)TEL: 02-2655-8198 / FAX: 02-2655-8196Email: algae@femico.com.tw

? (Chlorella) (Chlorella)- (Spirulina) (Spirulina) (10) Apogen ApogenApogen ApogenAPC (Apogen)EV71APC (Apogen) EV71 APC (Apogen) APC (Apogen)APC (Apogen)Apogen EV71Apogen ApogenApogen(Astaxanthin)DHADHA