7/29/2019 Amlodopine Drug Study

1/1

NAME OF DRUGAND

CLASSIFICATIONDOSAGE,

FREQUENCYAND ROUTE

MECHANSIM OFACTION

INDICATION CONTRAINDICATION ADVERSEREACTION

NURSINGRESPONSIBILIT

GENERIC NAME:

Amlodipine

BRAND NAME:

Norvasc

CLASSIFICATION:

Therapeutic: Anti-

hypertensives

Pharmacologic:

Calcium channel

blockers

2.5 g/tab OD Per orem

Inhibits the transport

of calcium into

myocardial andvascular smooth

muscle cells,

resulting in the

inhibition of

excitation

contraction coupling

and subsequent

contraction.

Therapeutic effects:

systemic vasodilation

resulting in thedecreased blood

pressure. Coronary

vasodilation resulting

in decreased

frequency and

severity attacks of

angina.

Alone or with

other agents in

themanagement of

hypertension,

angina pectoris

and vasospastic

angina.

Hypersensitivity. Blood

pressure less than 90

mmHg.Use cautiously in: sever

hepatic impairment,

history of CHF, aortic

Stenosis.

CNS: headache, dizziness,

fatigue

CV: peripheral edema,angina, bradycardia,

hypotension, palpitations

GI: gingival hyperplasia,

nausea

DERM: flushing

*Monitor blood pressu

pulse before therapy, d

dose titration, andperiodically during ther

Monitor ECG during

prolonged therapy.

*Monitor intake and ou

ratios and daily weight.

Assess for signs of CHF

(peripheral edema,

rales/crackles, dyspnea

weight gain and jugular

venous distention0

*Lab test consideration

Total serum calcium are

affected by calcium cha

blockers.

SOURCE: Daviss Drug Study Guide for Nurses (11th ed.)