-
Arterial stiffnessin Coronary Artery Disease
계명의대김기식, 이영수
-
김OO (F/72), Risk factor : none, TMT (+)
Dx : Angina pectoris
-
최OO (M/60), Smoking (+)
SPECT (+), TMT (+), Dx : Angina pectoris
-
민OO (M/61), Smoking (+), DM (+), HTN(+)
Dx : Angina pectoris
-
백OO (M/64), Risk factors : none,TMT (+), Dx : Angina
pectoris
-
4
6
8
10
12
14
0 1 2 3
PW
V (
m/s
ec)
Number of diseased vessel
P
-
0
2
4
6
8
10
12
14
Single Multiple
Number of diseased vessel
PW
V (
m/s
ec)
P
-
6.0 8.0 10.0 12.0 14.0
PWV (m/sec2)
0
5
10
15
20
25
Mod
ifie
d s
ten
osi
s sc
ore
sy
stem
Y=-7.726+1.422*X
r = 0.550, p
-
Control Cardiac syndrome X
5.0
6.0
7.0
8.0
9.0
10.0
11.0
12.0
Pu
lse
Wa
ve
Vel
oci
ty (
m/s
)P < 0.05
Increased Arterial Stiffness in Patients with Cardiac
Syndrome X
-
Increased aortic pulse wave velocity
in patients with TIMI 2 coronary flow
-
Arterial Stiffness, Wave Reflections, and the Risk
of Coronary Artery Disease
Weber T et al. Circulation. 2004;109:184-189
-
Caffeine Increases Aortic Stiffness
in Hypertensive Patients
Vlachopoulos C. Am J Hypertens 2003;16:63–66
-
PW
V (
m/s
ec)
AIx
(%
)
StudyPlacebo
Base 30 60 120 180 Base 30 60 120 1806
7
8
9
10
11
12
13
14
-25
-15
-5
5
15
StudyPlacebo
Acute Effect of Caffeine on Aortic Stiffness in Healthy
Subjects
-
Cigar Smoking Has an Acute Detrimental Effect
on Arterial Stiffness
Vlachopoulos C. Am J Hypertens 2004;17:299–303
-
Passive cigarette smoking in non-smoker would have acute adverse
effect on arterial stiffness
-
결 론
Augumentation index, pulse wave velocity를이용한 arterial stiffness의
측정은 관상 동맥 질환에서 병의 경과를 예측하고 치료 횩효과를 판정하는 중요한 변수로 인정되고
있으며 향후 많은 연구가 진행될 것으로 생각된다.
-
Thank You for Your Attention
-
박OO (M/53), Smoking (+)Dx : STEMI (ant. Wall)
-
김OO (M/65), Hyperlipidemia (+)
Dx : Angina pectoris
-
이OO (M/71) Risk factors : HTN
Dx : Angina pectoris
