Something wrong ?

Situs Inversus totalis Aziza Al-amri

Outlines .. Definition Prevalence Types Possible Causes Signs and Symptom Diagnosis Treatment Special concerns

Definition

Situs Inversus totalis is a genetic condition that causes the organs in the chest and abdomen to be positioned in a mirror image from their normal positions.

• Eg. In the abdominal cavity, the liver is positioned on the left side instead of the right, and the stomach is on the right side instead of the left.

Prevalence

Situs inversus totalis has been estimated to occur once in about (8-10,000) births.

20% of patients with situs inversus have a rare abnormal condition called Kartagener's syndrome.

Only 50% of patients with Kartagener syndrome have situs inversus

Types

Situs inversus totalis

Situs inversus thoracalis

Situs inversus abdominalis

All organs are transposed in a mirror image of the normal positioning

Only lungs and heart

Liver, stomach and spleen

Situs inversus totalis

LevocardiaDextrocardia

Possible Cause !

• Mutation in the coding region of DNAH11(Bartoloni et al., 2002).

• Developmental stage of an embryo !

Signs and Symptom

• No medical symptoms or complications .• 3-5% have functional heart defect• 25% have an underlying condition called

primary ciliary dyskinesia (PCD)

DiagnosisIt can be detected using• X-ray• CT• MRI• Ultrasonography

A doctor/RT may suspect• Heartbeat ?

Treatment

• No cure for situs inversus.• If other complications are present,

the symptoms will be treated accordingly.

Special concerns !

• Failure to recognize situs inversus ?• Attention to the left and right sides of the

patient and the left and right labeling of images .

• Organ donation !

At the end ..