Cardiovascular Ultrasound- 2009

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Cardiovascular Ultrasound- 2009. Yun Zhang, MD, PhD, FACC Shandong University, China. . 2007 271.6 34% 11.6 1 3 34 1 10 - PowerPoint PPT Presentation

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  • Cardiovascular Ultrasound-2009

    Yun Zhang, MD, PhD, FACC Shandong University, China

  • 2007271.634%11.61334110200256842007109665

  • Ding SF, et al. Am J Med Sci. 2008,336:27-31

  • TCRPMMPTIMPsCD40Lox-LDLLp-PLA2 sPLA2 MPOMCP-1 [6970]

    1.[B]2. [C]

  • Zhang PF, et al. J Hypertens, 2009;27:348-356

  • Zhang PF, et al. J Hypertens, 2009;27:348-356

  • Zhang PF, et al. J Hypertens, 2009;27:348-356

  • Logistic HR 95%CI p LSp (%) 0.386 0.145~0.820 0.007 CSp (%) 8.446 5.904~9.104 0.001 RSp (%) 8.963 5.358~10.486 0.001

  • ROCCSpRSp0.268%0.296%88.6%88.0%92.0%88.6%0.9650.963CSpRSp

  • Su HJ, et al. Sci China Series G. 2004, 47(7):452-462Su HJ, et al. Sci China Series G. 2008, 51(7):867-872

  • IVUS

  • Chen WQ, et al. Am J Physiol Heart Circ Physiol, 2007, 293:2836-2844

  • Plaque Rupture Predictors in Rabbits (Logistic Regression) Chen WQ, et al. Am J Physiol Heart Circ Physiol, 2007, 293:2836-2844

    Predictors OR P

    EI 7.056 0.003PAmm2 1.942 0.032hsCRP(ng/mL) 1.025 0.006AIIc%dB 0.856 0.002

  • ApoE-/-ABeginning of the experiment (bar=200um)BEnd of the experiment (bar=200um)

  • ApoE-/-FHistopathology H&E End of the experiment Control group: Concentric Plaque D and EMicro-ultrasound Imaging bar1mm

  • Multivariate Logistic Regression Analysis Factors SE p OR 95%CI for OR IMT (mm) 0.017 0.007 0.01 1.017 1.004 1.030 Vmax (m/s) 0.005 0.002 0.008 1.005 1.001 1.009 Plaque Rupture Predictors in MiceNi M, et al. Atherosclerosis, 2007, 197:67-71

  • Plaque Rupture Predictors in Patients (Logistic Regression) Chen WQ, et al. Am J Cardiol, 2007,100:1341-1346

    Predictors ORP 95%CI IMT (mm) 9.500 0.0291.256~71.861 hs-CRP(mg/L) 2.9160.0391.057~8.045 RI0.0100.0120.000~0.364

  • LAD75

  • LAD75

  • LAD75

  • TTCYao GH, et al. Ultr Med Biol, 2008,34:22-30

  • LAD75% Yao GH, et al. Ultr Med Biol, 2008,34:22-30

    (%) (%) ROC A 13.457.169.00.54 1.4585.766.70.69A 19.771.464.30.61A-endo 14.057.161.90.50-endo 1.4392.966.70.69A-endo 22.185.761.90.60A-EER 0.9457.152.40.62-EER 0.8992.961.90.75A-EER 0.8692.961.90.69WT(%) 32.050.038.10.37

  • Measurement of LA Volume

  • Measurement of LV Volume

  • Comparison of CMRI and Echo

  • Difference between LVEDV by CMRI and RT-3DE in both Groups****** P
  • Difference between LAVmax by CMRI and RT-3DE in both Groups****** P
  • AMILV conic index LV conic index = RT-3DE LV volume/LV conic volume V = h =(cm) D = (cm) Li F, et al. Am J Cardiol, 2008,102:1433-1437

  • AMI RT-3DE LVd conic index > 3.87 100% 90.9% AUC 0.989 LVd sphericity index > 0.28 83.3% 95.5% AUC 0.891 LVEDVLVESVLVEFWMI DT Li F, et al. Am J Cardiol, 2008,102:1433-1437

  • 6612QTVIQTVIQRSTsTe TsTe

  • 11111111111111111111

  • LVHNLVH

    Ts-max>88 ms71.0%LVH37.2%NLVHX2=10.45P=0.001 Te-max>73 ms29.0%LVH10.7%NLVHX2=5.76P=0.02 Tan HW, et al. J Hypertens, 2008,26:553-559

  • MS135MS >25>90cm>85cmTG>150mg/dlHDL
  • Li SH, et al. J Hypertens. 2009, 27: 869-875

  • ASDTEELi GS, et al. Ultr Med Biol, 2009,35:58-64

  • ASDTEELi GS, et al. Ultr Med Biol, 2009,35:58-64

  • ASDTEELi GS, et al. Ultr Med Biol, 2009,35:58-64

  • LAD75flash78

    flash78A

    A LAD75-EER A-EER TTC13.457.169.00.541.4585.766.70.6919.771.464.30.6114.057.161.90.501.4392.966.70.6922.185.761.90.600.9457.152.40.620.8992.961.90.750.8692.961.90.693250.038.10.3713.457.169.00.541.4585.766.70.6919.771.464.30.6114.057.161.90.501.4392.966.70.6922.185.761.90.600.9457.152.40.620.8992.961.90.750.8692.961.90.693250.038.10.37