drugstudy(OSMAK)

7/27/2019 drugstudy(OSMAK)

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IX. DRUG STUDY:

DRUGNAME ACTION DOSAGE INDICATION CONTRAINDICATION ADVERSE REACTIONNURSING

RESPONSIBILITIES

Generic name:

LOSARTAN

Brand name:

Cozaar

Classification:

cardiovascular

agent;

antihypertensive

Angiotens in II

receptor (type

AT1)

antagonist acts

as a potent

vasoconstrictor

and primary

vasoactive

hormone of the

renin

angiotensin

aldosterone

system.

50 mg

tab/ OD

*Treatment of

hypertension; in

heart failure and

myocardial

infarction, it may

be used alone or

incombination with

other

antihypertensive

agents.

*Renal protection

in type 2 diabetic

patients with

proteinuria.

*renal artery stenosis,hyperkalemia,hypersensitivity, anuria,patients who arehypersensitive to othersulfonamide-deriveddrugs

CNS: Dizziness, insomnia,

headache.

GI: Diarrhea, dyspepsia.

Musculoskeletal:

Muscle cramps, back or

leg pain.

Respiratory:

Nasal congestion, cough,

upper respiratory infection,

sinusitis

*Assess patients blood

pressure before starting

therapy and regularly and

pulse rate.

*Obtain baseline liver and

renal function before therap

and regularly assess kidney

function BUN and creatinin

*Monitor forpossible advers

drug reaction

*Assess for hydration statu

mucous membranes and s

turgor

*Assess patients familys

knowledge of Drug therapy


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DRUGNAME ACTION DOSAGE INDICATION CONTRAINDICATION

ADVERSEREACTION

NURSINGRESPONSIBILITIES

Generic name:

Amlodipine

Brand name:

(Norvasc)

Classification:

Antihypertensive

Calcium Channel

Blocker

Inhibits the movement

of calcium ions across

the membranes of

cardiac and arterial

muscle cells; inhibits

transmembrane

calcium flow, which

results in depression of

impulse formation in

specialized cardiac

pacemaker muscles,

slowing the conduction

of the cardiac impulse,

depression of

myocardial contractility

and dilation of

coronary arteries and

arterioles.

10mg/

tab (OD)

PO

*Treatment of

hypertension

*Contraindicated withallergies to amlodipine,impaired hepatic orrenal function, heartblock

*Use cautiously with

heart failure

CNS: fatigue,

lethargy

* Administer drug with

food or meals if GI upset

occurs

*Monitor patient carefully

*Monitor cardiac rhythm

regularly

*Report irregular

heartbeat, shortness of

breath, swelling of hands

or feet, dizziness


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ADVERSEREACTION


Generic name:

citicholineBrand name:

(Zynapse)

Classification:

Neurotonics

Citicoline activates the

biosynthesis ofstructural

phospholipids in the

neuronal membrane,

increases cerebral

metabolism and

increases the level of

various

neurotransmitters,

including acetylcholine

and dopamine.

Citicoline has shown

neuroprotective effects

in situations of hypoxia

and ischemia.

100mg/ml

(TID)

Cerebrovascular

Diseases,accelerates the

recovery of

consciousness

and overcoming

motor deficit.

*Hypertonia of the

parasympathetic

Body temperature

elevation Restlessness

Headaches

Nausea and

vomiting

Diarrhea

Low or high blood

pressure

Tachycardia

Sleeping troubles

or insomnia

Blurred vision

Chest pains

Citicoline may be

taken with or withoutfood. Take it with or

between meals.

The supplement

should not be taken in

the late afternoon or at

night because it can

cause difficulty

sleeping.

Contact the physician

immediately if allergic

reaction such as hives

rash, or itching,

swelling in your face o

hands, mouth or

throat, chest tightness

or trouble breathing

are experienced.

Watch out forhypotensive effects


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ADVERSEREACTION


Generic name:

metoprololBrand name:

(Prolol)

Classification:

Anti-hypertensivedrugs (beta-blockers)

*Exerts mainly beta1-

adrenergic blockingactivity but also blocks

beta-2 receptors at

high doses. It

reversibly and

competitively combines

with beta-1 adrenergic

receptors to block

sympathetic nerve

impulses, resulting to

decreased myocardial

contractility, heart rate,

cardiac output and

myocardial oxygen

consumption.

50 mg/tab

BID

Indicated to

hypertension.

*Contraindicated tokidney and liver failure

Fatigue

Dizziness Headache

Bradycardia

GI disturbances

Skin rashes

Sleep

disturbances

Sweating

Abdominal pain

Vomiting

Assess patients

condition beforetherapy and regularly

thereafter to monitor

drug effectiveness

Monitor vital signs

specially the BP

Do not crush or chew

tablets

Monitor urine output

Tell patient to avoid

taking OTC products

containing alpha-

adrenergic stimulants

(such as nasal

decongestans, cold

preparations), alcohol,

smoking and to limit

sodium intake.

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drugstudy(OSMAK)