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Gerovitalul!
http://ar.iiarjournals.org/content/24/2B/1003.full.pdf
Am subliniat pasajele care mi se par semnificative n leg!tur! cu
rolul sistemuluinervos n patologia cancerului "i cu faptul ca
mecanismul concret nu era nc! cunoscut#2004$.
%&ancer survival decreases in patients e'periencing various
ps(chosocial stresses #1$)suggesting a potential role for the
central nervous s(stem in progression of malignanc(.*pecificall()
stress+ induced changes in neuroendocrine and immune functions
ma(contribute to cancer mortalit( #2$. *tress not onl( alters the
neuroendocrine s(stem) butalso modifies sensor( nerve
function.,
-ata de supravieuire n cancer descre"te n caul pacienilor
confruntai cu diferitetipuri de stres psihosocial #1$) situaie care
sugerea! un potenial rol pe care sistemul
nervos central l joac! n evoluia procesului de maligniare.
&oncret) schimb!rile indusede stres la nivelul funciilor imune
"i neuroendocrine pot contribui la mortalitatea ncancer #2$.
*tresul nu numai c! alterea! funcionarea sistemului neuroendocrin
darmodific! "i funcia nervilor senitivi.
*tresul mai i mb!trne te nu+i a a 1. eurons sensitive to
capsaicin mediate inflammator( pain and are important targetsfor
management of chronic pain. hese neurons also regulate local tissue
homeostasis)inflammation) healing and development) especiall( under
conditions of ps(chologicalstress. *tress contributes to increased
cancer recurrence and metastasis through as (etundefined
mechanisms.i5e6ise) activit( of capsaicin+sensitive neurons is
altered b(pathological conditions that ma( lead to metastatic
gro6th #e.g. stress$. herefore) 6e
e'amined effects of a treatment that induces sensor( nerve
denervation on breast cancermetastases.
1. euronii sensibili la capsaicina media! durerile cauate de
procese inflamatorii "isunt obiective importante de urm!rit n
managementul durerilor cronice. Ace"ti neuronicontrolea! homeostaia
#stabilitatea unor parametrii normali$) la nivel local)
alesuturilor) procesele de inflamaie) de vindecare "i cre"tere) n
special n condiii de strespsihologic. *tresul contribuie la
cre"terea probabilit!ii de revenire a cancerului "i demetastaare
printr+un mecanism) nc!) necunoscut.7e asemenea) activitatea
neuronilorsenitivi sensibili la capsaicina este alterat! de condiii
patologice #de e'emplu stres$ carepot duce la o evoluie
metastatica. 8n aceast! idee am e'aminat efectele unui
tratamentcare induce denervareanervilor senitivi n metastae ale
cancerului de sn.
http://666.scribd.com/doc/93912;00;2? @n vitro studies have
indicated that botulinum to'in inhibits potassium cationinduced
release of both achet(lcholine and norephineprine from primar( cell
culturesof brain+stem tissue. Additionall() it has been reported
that botulinum to'in inhibits theevo5ed release of both gl(cine and
glutamate in primar( cultures of spinal cord neurons
http://ar.iiarjournals.org/content/24/2B/1003.full.pdfhttp://www.scribd.com/doc/93912576/Cancer-American-Patent-2005http://ar.iiarjournals.org/content/24/2B/1003.full.pdfhttp://www.scribd.com/doc/93912576/Cancer-American-Patent-2005
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and that in brain s(naptosome preparations botulinum to'in
inhibits the release of each ofthe neurotransmitters acet(lcholine)
dopamine) norepinephrine) &-= and glutamate.
>00;2? *tudiile in vitro au indicat faptul c! to'ina
botulinic! inhib! eliberarea de cationide potasiu care induc
eliberarea de acetilcolin! "i norefineprin! din culturi primare
de
celule din esutul stem cerebral . 8n plus) s+a raportat c!
to'ina botulinic! inhib! eliberareamen ionat! att de glicin! "i ct
"i de glutamat n culturi primare de neuroni) m!duvaspin!rii "i c!)
n produsele sinaptosome din creier) to'ina botulinic! inhib!
eliberareafiec!ruia din neurotransmi !torii acetilcolin!) dopamin!)
noradrenalin!) &-= "iglutamat .
&um procaina #ca "i lidocaina+'ilina$ este un anesteic
local) acolo) la locul faptei)rela ia ei cu neurotransmi !torii
este direct!: inhib! ac iunea acestora.
http://medicamente.romedic.ro/clorhidrat+de+procaina+sol+inj
http://666.scribd.com/doc/;
