Pt Anpmidterm Paper Jan 15br

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    KUALA LUMPUR METROPOLITAN UNIVERSITY COLLEGE

    COSMOPOINT INTERNATIONAL COLLEGE OF TECHNOLOGY

    HDP 112 -ANATOMY AND PHYSIOLOGY 2

    MID TERM EXAMINATION: JANUARY 2015

    SECTION - A

    Ans!" #$$ %&! '($%)*$! +&,)+! (!s%),ns .)/!n !$,:  10 1'#" 3 10 '#"s Shade your answer in the shading sheet provided 

    1. The base of the heart lies in the ____________.

    A 2nd intercostal space-left side

    B 2nd intercostal space-right side

    C 5th intercostal space –left side

    D 5th

     intercostal space-right side

    2. The impulse for cardiac contraction starts at___________.

    A A node

    B A! nodeC Bundle of his

    D "ur#in$e fiber  

    % The $unction &here the trachea and the t&o primar' bronchi branch is

    reinforced b' a cartilage plate called the _______.

    A Tracheal cartilage

    B Corniculate cartilageC !entricular cartilage

    D Carina

    ( The )er' small functional units of the lung is*

    A Al)eoli

    B Al)eolar ductC Terminal bronchiole

    D +espirator' bronchiole

    5 Tidal )olume is air ________.

    A remaining in the lungs after forced e,pirationB e,changed during normal breathing

    C inhaled after normal inspiration

    D forcibl' e,pelled after normal e,piration

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    "rocesses that carr' ner)e impulses a&a' from the cell bod' are called

    A dendrites.B a,ons.

    C s'napses.

    D m'elin sheaths

    /. 0hat is function of the oligodendroc'tesA. create m'elin la'er  B. clean up cellular debris

    C. suppl' blood and nutrients

    D. alert the bod' to an infection

    The sali)ar' glands in the human bod' are _________.

    A "arotid gland3sub-ma,illar' gland3sublingual gland

    B "aratid gland3sub-ma,illar' gland3 submandibular gland

    C "aratid gland3submandibular gland3sublingual glandD ubmandibular gland3 subma,illar' gland3 sublingual gland

    4 0hich of the follo&ing is the function of li)er

    A +elease pepsinB +eser)oir for bile

    C ecrete insulin

    D Deto,ification of drugs

    1 6ullet is another name for ________ 

    A 7eshopagus

    B 7rophar'n,C tomach

    D mall intestine

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    SECTION - 4

    Ans&er ALL  of the follo&ing SHORT  8uestions* 5 '#"s 3 20 '#"s

      1. Describe structure of heart chamber and )al)es. 95 mar#s:

    2 9a: 0hat is ;C6 92 mar#s:

    9b: 0rite on normal ;C6 &a)eform. 9% mar#s:

    %. Describe in details on h'po,ia. 95 mar#s:

    (. 0ith the help of a labeled diagram3 e,plain in details the different part of 

    neuron.

    95 mar#s:

    SECTION - C

    Ans&er ANY ONE  of the follo&ing ESSAY  8uestions* 1 20'#"s 3 20 '#"s

    1 ;,plain in details the structure of the lungs under the follo&ing headings.

    .

    9a:

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    KUALA LUMPUR METROPOLITAN UNIVERSITY COLLEGE

    COSMOPOINT INTERNATIONAL COLLEGE OF TECHNOLOGY

    HDP 112 ANATOMY AND PHYSIOLOGY 2

    SOLUTION

    67N, S,$(%),n S(M#"s T,%#$

    '#"s

    >uestion A1 9a : mm?g 1 mar#s 1 mar#s

    >uestion A2 9c: 5th intercostal space-left side 1 mar#s 1 mar#s

    >uestion A% 9c: Aorta 1 mar#s 1 mar#s

    >uestion A( 9c: "ulmonar' arter' 1 mar#s 1 mar#s

    >uestion A5 9 c: To #eep dust out of the lungs 1mar#s 1 mar#s

    >uestion A 9A: A node 1 mar#s 1 mar#s

    >uestion A/ 9d: ;piglottis 1 mar#s 1 mar#s

    >uestion A 9d: Carina 1 mar#s 1 mar#s>uestion A4 9a: al)eoli 1 mar#s 1 mar#s

    >uestion A1 9a: al)eoli 1 mar#s 1 mar#s

    >uestion A11 9c :?'po,ia 1 mar#s 1 mar#s

    >uestion A12 9b: e,changed during normal breathing 1 mar#s 1 mar#s

    >uestion A1% 9a: c'anosis 1 mar#s 1 mar#s

    >uestion A1( 9b: pons and medulla 1 mar#s 1 mar#s

    >uestion A15 9a:A @7D; 1 mar#s 1 mar#s

    >uestion A1 9a: ?+ ! 1 mar#s 1 mar#s

    >uestion A1/ 9a:"arotid gland3sub-ma,illar' gland3sublingual gland 1 mar#s 1 mar#s

    >uestion A1 9d: deto,ification of drug 1 mar#s 1 mar#s

    >uestion A14 9a: renal hilum 1 mar#s 1 mar#s

    >uestion A2 9a: 7eshopagus 1 mar#s 1 mar#s

    >uestion B1 Breathing during exercise During exercise the muscle cells use up

    more oxygen and produce increasedamounts of carbon dioxide.

     The lungs and heart have to work harder to

    supply the extra oxygen and remove thecarbon dioxide.

    breathing rate increases and also

    becomes more deep. More oxygen is used by the cells for activity. So

    internal respiration increases; gasexchange increases at tissue level.

    More CO2 is produced

     The brain detects increasing levels of  CO2 – a

    signal is sent to the lungs to increasebreathing.

    Breath rate and depth increases.

    as exchange at lung level(external respiration)increases.

    5 '#"s 5 '#"s

    >uestion B2 The chest &all is formed b' 12 pairs of ribs3 strernum3costal cartilage and the 12 thoracic )ertebrae.

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    1st rib- during inspiration the 1st rib ele)ates and mo)es

    superiorl' and posteriorl' at costo)etebral $oints and pushes the manubrium superiorl'. This increases the

    )ertical diameter of the rib cage.

    2nd rib-th rib – During inspiration3 the upper half ofribs mo)es superiorl' and anteriorl' increasing the

    anterio-posterior diameter of the thora,9"ump handle

    mo)ement:.

    /th-1th ribs- during inspiration the lo&er half of theribs mo)es superiorl' and laterall' increasing the

    lateral diameter of the thora, 9Buc#et –handle

    mo)ement:

    11-12th ribs – the' can mo)e in an' direction because

    the' dont ha)e an' attachment &ith sternum.

    5 '#"s 5 '#"s

    >uestion B% The Cardiac C'cle

    tages of Cardiac C'cle.

    Cardiac c'cle occurs due to*

    'stole- period of contraction

    Diastole – a period of rela,ation of the heart chambers.

    tages of Cardiac C'cle

    Atrial 'stole - contraction of atria-.1 sec!enticular 'stole –contraction of )entricles-.% sec

    Complete Cardiac Diastole – rela,ation of the atria

    and )entricles -.( secs

    A%")#$ +,n%"#+%),n * Anode triggers causing atrial

    contraction. Blood from the atria enter into the)entricles.

    V!n%")+($#" s8s%,$! * A! node troggers and impulse

    tra)el through the )entricles. !entricles contract3

    Atrio)entricular )al)e close3 aortic and pulmonar')al)e open. Blood from the )entricles flo& into the

    aorta and the pulmonar' arter'.

    C,'*$!%! +#"9)#+ 9)#s%,$! – after contraction of the

    )entricles there is a complete cardiac diastole &hen theatria and )entricles are rela,ed. Aortic and pulmonar'

    )al)es close3 &hile atrio)entricular )al)es open. The

     blood from the )eins fill the t&o atria- superior and

    inferior )ena ca)a fill the right atrium and the pulmonar' )eins fill the left atrium. The

    5 '#"s 5 '#"s

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    atrio)entricular )al)es are open and blood flo&s to the

    )entricles passi)el'.

    >uestion B( 9a:

    6as e,change is the e,change of respirator' gases9o,'gen and carbon dio,ide: bet&een tissues and

     blood.

    1 '#"s

    5 '#"s

    9b:actor affecting gas e,change*

    -The thic#ness of the membrane* this comprises the

    thic#ness of the al)eolar &all3 capillar' &all and the

    interstitial membrane. The thic#er the membrane the

    lesser gas e,change.

    -The surface area of the membrane* These comprise

    the surface area a)ailable for gas e,change. The more

    the surface area3 the more gas e,change.

    -The diffusion coefficient of the gas through themembrane the more the diffusion gradient3 the greater 

    is the gas e,change

    -The partial pressure difference of the gas bet&een the

    t&o sides of the membrane this comprises the

    difference in the amount of gas present in the tissue

    and the blood. The greater the difference in the partial

     pressure3 the more gas e,change.

    '#"s

    >uestion B5 ;lectrocardiogram*

    9a: Definition*An electrocardiogram is a non-in)asi)e procedure for

    recording of the electrical signal produced b' heart

    muscle fibers during each heartbeat3

    2 '#"s

    5 '#"s

    9b: ;C6 @ormal &a)eform- " &a)e –represent atrial depolariEation.

    - >+ comple, – represent )entricular depolariEation

    - T &a)e –represent )entricular repolariEation

    '#"s

    >uestion B   hypoxia is a pathological condition in !hichthe body as a !hole or a region of the bodydoes not receive adeuate oxygensupply.

    "f the body is a!ected as a whole it is

    called generali"ed hypoxia

    "f the part o# the body is a#ected it is

    called tissue hypoxia.

    Clinical #eaturesDepressed mental activity$ sometimesculminating in coma$ and

    5'#"s 5 '#"s

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    reduced !or% capacity of the musclesheadaches$fatigue$shortness of breath&auseaDeath'if severe hypoxia

    >uestion B/ 9A:Cardiac output is defined as the 8uantit' of blood

     pumped b' heart in 1 minutes.

    Cardiac outputF heart rateG stro#e )olume

    1 '#"s

    5 '#"s

    actor affecting cardiac output*

    There are three important factors that affect the

    cardiac output*

    - "reload-Contractilit'

    -After load

    "reload* preload means the amount of blood coming

     bac# into the heart through the )eins. =ore preload

    greater is the cardiac output.

    Contractilit'* it is the abilit' of the heart to produce a

    strong contraction.

    Contractilit' depends on the inotrophic agents

    After load* it is the amount of bac# pressure that the

    heart has to o)ercome before the semilunar )l)e canopen and blood flo& out into the aorta and pulmonar'

    arter'. =ore the afterload lesser is the cardiac output.

      '#"s

    >uestion B  The ma(or function of the %idney is to maintain

    the )uid and electrolyte balance of )uids *emove toxic !aste products

    *emove excess !ater and salts

    +roduce erythropoietin !hich stimulates red cell

    production from the bone marro! ,elp to %eep calcium and phosphate in balance

    for healthy bones Maintain the blood in a neutral 'non-acid state

    5 '#"s 5 '#"s

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    67N,7 S,$(%),n S(M#"s T,%#$M#"s

    >uestion C1

    9a: The heart is a hollo& muscular organ in the

    thoracic ca)it'

    • C'!"s ,; %&! &!#"%: The heart has (

    chambers.

    o The t&o chambers on the right side are

    called right atrium and right )entricle

    o The t&o chambers on the left side are#no&n as the left atrium and left )entricle

    o The left and right atria are smaller in siEe3

    the upper chambers of the heart. The atriaare separated b' interatrial septum.

    o The left and right )entricles are larger in

    siEe3 the lo&er chambers of the heart. The

    t&o )entricles are separated b'

    inter)entricular septum.

    • V#$/!s ,; %&! &!#"%: The heart has ( )al)es.

    o The opening bet&een the right atrium and

    the right )entricle is guarded b' thetricuspid )al)e - right atrio)entricular

    9A!: )al)e.

    o The opening bet&een the left atrium and

    the left )entricle is guarded b' the

     bicuspid )al)e -- =itral )al)e - leftatrio)entricular 9A!: )al)e

    o The opening bet&een right )entricle and

     pulmonar' arter' is guarded b' the

    "ulmonar' )al)e.

    o The opening bet&een the left )entricle

    and the aorta is guarded b' the Aortic)al)e.

    4 mar#s

    2 mar#s

    9b:

    • L#8!"s ,; %&! &!#"%: The heart has % la'ers

    o The innermost la'er is called

    endocardium

    o The middle la'er is made of cardiac

    muscles called m'ocardiumo The outermost la'er is called the

     pericardium

    o The pericardium is di)ided further as the

    fibrous pericardium and the serous

     pericardium

    o The serous pericardium is further di)ided

    into )isceral and parietal pericardium

    o The pericardial fluid is present bet&een

    these t&o la'ers

    mar#s

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    9c:

    • C,",n#"8 +)"+($#%),n: The heart recei)es

     blood suppl' through the right and leftcoronar' arteries. The' are the first branches

    of aorta.

    o =ain branches of +ight coronar'

    arter'*- "osterior inter)entricular branch- =arginal arter'

    o =ain branches of left coronar' arter'*

    - Anterior inter)entricular branch

    - Circumfle, arter'

    !enous blood of heart is collected b' the +,",n#"8s)n(s7 Ht opens directl' into the right atrium.

    !eins draining into coronar' sinus are*

    • 6reat cardiac )ein

    • =iddle cardiac )ein

    • mall cardiac )ein

    5 mar#s

    >uestion C2 9a:

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    =HDD

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    run bet&een the ribs3 and help form and mo)e

    the chest &all.• the e,ternal intercostal muscles3 &hich aid in

    8uiet and forced inhalation. The' originate on

    ribs 1-11 and ha)e their insertion on ribs 2-

    12. The e,ternal intercostals are responsible

    for the ele)ation of the ribs.•

    d: diaphragm

    The diaphragm is a sheet of internal muscle thate,tends across the bottom of the rib cage.

    The diaphragm separates the thoracic ca)it' 9heart3

    lungs K ribs: from the abdominal ca)it' and performs an important function in respiration

    • 7rigin *- ternal* bac# of the ,iphoid process

    - Costal* the inner surfaces of the lo&er si, ribs

    on either side-

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    the diaphragm.

    I@CTH7@ 7 T?; T7=AC?

    Bolus 9masticated food: enters the stomach through the

    esophagus )ia the esophageal sphincter.

    The stomach releases proteases9 protein-digesting enE'mes

    such as pepsin: and h'drochloric acid3 &hich #ills or

    inhibits bacteria and pro)ides the acidic p? for the

     proteases to &or#.

    LIVER 

    The li)er is the largest internal organ of the

    abdomen3 triangular in shape and lies on theright side of the abdominal ca)it' $ust belo&

    the diaphragm.

    The li)er is a )ital organ3 pla's a ma$or role inmetabolism and has a number of functions in

    the bod'.

    The li)er has 7I+ lobes

    uadrate lobe

    olds of peritoneum form the supporting

    ligaments attaching the li)er to the inferiorsurface of the diaphragm.

    I@CTH7@ 7 T?; uestion C(

    9a:

    C;

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    A,on is a longitudinal3 tubular e,tension of the cell

    membrane and c'toplasm.

    The function is to transmit information a&a' fromthe cell bod'3 the cell membrane surrounding the

    a,on is referred to as a,olemma.

    D;@D+HT;The' are processes of the cell membrane that radiate

    from the cell bod' in )arious directions and are

    responsible for recei)ing information andtransmitting it to the cell bod'.

    9b:

    T+ICTI+; 7 A ";+H"?;+A< @;+!;

    A peripheral ner)e is formed b' a number of a,ons.The siEe of the ner)e depends on the number of

    a,ons.

    Hndi)idual m'elinated a,ons are surrounded b' atubular sheath of fibrous tissue called endoneurium.

    A group of a,ons are held together b' a larger

    fibrous sheath called perineuriumA bundle of a,ons held &ithin a perineurial sheath is

    called as a ner)e fascicle.

    The fascicles inside a peripheral ner)e is bound b'

    an e,ternal sheath of fibrous tissue called epineurium

    1 mar#s

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