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4. Asociere de
Diuretice
AntiHTA 1. Diuretic + BB Principiul: Sinergism-efecte pozitive
prin 2 mecanisme diferite
2. Diuretic + IEC Antagonism-eff adv
3. Ca Bloc din tulb de ritm + BBprotecrot fata de tulb de ritm4.
Ca Bloc + IEC eficienta in scaderea TA5. BB + B rar
AA: 1.IA(Clonidina, Procainamida)+IB(Mexiletina)Can Na Activ vs
Can Na Inact Interz: 1.Nu se Asc ac Cls/SubCls:IA+IC
2. I+BB(no Sotalol) 2.Dc QT NU IA, Amiod, Sotalolalte :
1.Propranolol+Metixilina/Flecainida - Diminua Efectul Proaritmic 3.
Amiod+BB eff Aditive
2.IA+Sotalol - Date clinice incomplete
3.Clonidina+Verapamil Hipotensiune
4.Disopiramida+Verapamil
5. Propafenona+Chinidina/Procainamida
5. Indicatii :Aritmie+HTA:1.BB selective, 2.Ca Bloc Verap.Dilti
(DupaK posttrat diurfavor EctopiiV Proaritmigene6. Eff Adv: CI
AA:
AA 1. Amiodarom: Fibr Pu, Neuropat Perif, Depoz Cornee, Disf
Hep+Tir, B.Pu, Hep, Neuropat
2. BB: BeSpasm, HiperGlic Asm, D-InsDep
3. CaBloc: Icc, BAV Disf V, Tulb Cond
4. Disopiarmida: ICC, Torsada Vf, Ret Urin,Glauc, Creste QT,
Tulb Ritm QT>, Prostatism, Glaucom, IR5. Flecainida: Creste
Mortalitatea Post IM, BradiAritm Tulb Cond,
6. Procainamida: Sdr.Lupoid, Agranulocitoza Artrita Cr,
Discrazie Sg
7. Lidocaina+Mexilitina: Tremor Parkinson
8. Propafenona: ICC, BrSpasm, ProArtim Asm, Tulb Cond, Disf
VS
9. Chinidina: Torsada Vf, Creste QT, Diaree, HipoK B.Dg Cr,
Qt>, HipoK
10. Sotalol: Torsada Vf, BrSpasm, DZInsDep Asm, DZ InsDep,
QT>, HipoK
Brdilat 2Adr:Toleranta,Agitatie, Tremor, Nervoz, Cefalee,
Transpir, Slabici, Roseata Pielii, Greata, Voma Aritmii HTA,
HipoK+
CoSt:Sistemic-1.Metab-Intol Gluc, Obez, Dislip, Proteoliz;
2.Os:AbsCA, NecrAvsc Cap Femur, Osteopor;
3.CV:Retent.Hd, HTA, ATS; 4.Supresia Sys Imm-Vulnerab La Inf;
5.M.Striata;Miopatie, Mas Musc, 6.Piele-Atrofie,
7.HipoGonadism8.Ulcer Peptic, 9.Cataracta, 10.Neuro:Euforie,
Depresie, Tulb Somn, Ideatie Psihotica, 11.Tulbcopii:secr
horm de, Inhib Ef Fact de Insulin Like, Local: Disfonie-Fav dezv
Fungi Candid OroFar, Iritatia, Gat Tuse
Stabil Mast: Cefalee, Gat uscat, Iritatie, BrSpasm tranzitoriu,
Tuse, Roseata Tegumentara
Sulfasalazina:Cefa Fe Greata Diaree DiscGastric, Anemie
Megalobabs Ac.Fol, R.Alerg:Artralgii, Hemoliza, Agrnul, Tt-penie
,
ImmSupr:DerivTioguanina-Suprima MadHePoet, 2.Mtxat-SupresMed,
Alopecie, Nefrotox, EpitIntest, 3.Inflix-InfRespSupIgASecrt
IPP: Omeprazol-HiperGastrienemie Secundara, HiperPlazia Mucoasei
Gastrice
TeofilinaC-V: TahicSinusala, TSV, ESV, FiA, Ftt, TahicAtriala,
TahicMultifocala, Aritmie cu instabilitate hemodinamica
6. AA Neclasificate:1.Atropina -Bradic Sinusala, 2.Adrenalina -
Stop, 3.Izoprenalina-Bloc, 4.Dogoxin - FiA, .. 5.Adenozin-TSV,
6.CaCl2 - TV PrinHiperK, 7.MgCl2 - FiV, Intoxi Digitala, Torsada
Vf
7. Efecte CoSt: Confirmat:Inh Local:Nev De Cssyst, simpt sau
Exacerb AB,Nev DeBrDiladr de urgenta,Crize Noct /Echivalent AB Noct
-Tuse, Imbunatat Indici Calitate Vietii , Ameli Fct Pu,
Posibil:Cz Deces, Vit Declin Fct Pu, Per De Remisie Sustinuta a
Crizelor
8. Efecte BrhDil:BrDil, StabMast, Inhib Eliber LT, PermeabVasc,
Exudat+EdemCA, Clearance MucoCil, Secr Mucus9. Sv BBin IC: Risk De
aritmii- Eff Anti Aritmic, Prin Activ Simpatice In ICC
10. Clase de Medicamente in IC: IEC, BB, Ca Bloc, Nitriti,
Diuretice11. Medicamente ce actioneaza pe Alfa 2 Centrali:
Clonidina12. Cond Pat HTA+BB: Angina P, Post IMA, ICC, Sarcina,
Tahiaritmii, Cele cu Act Intrinseca- Sunt Tahicardizante=CI
13. NU se daHTA+BB: Obligatorii-Astm, BPOC, BAV 2/3,
Posibile:BoalaVascPerif, Intoler la Gluc, Pers Fiz Active
-Atleti
14. Cond Pat Ce Det Aritmii:TS: Durere, HipoVol, IC, Tireotox,
Anxietate
15. In ce aritmii se da Digoxina: Fi A: 62,5-250g/zi p.o.
corelata cu varsta
16. TorsadaVarfuri: MgCl2-2g in 1-2 min, repetat la 5-10 min,
Alternativ Isoproterenol sau Pacing ( QT )17. Genza Torsada: Bloc
K+, Antihist, Fenotiazide, AntiDepres3Ciclice, Ketoconazol, Dieta
proteica Lichida
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18. AAQT: Quinidina Disopiramida Amiodarona Sotalol Bepidil
Probucol Prenilamida Der.Triciclici FenitiazinaEritromicina
Antihistaminice:Terfenadina Astemizol ; Creste QT pe fond de hipo
K+Mg+
19. AAPRR--
20. AA Proaritmogene: IC,A, III-Sotalol
21. Cum actioneaza Clasa I pe PRefract22. Cum actioneaza Clasa I
pe PA:1a-, 1b-
23. Cum Actioneaza Clasa III: Durata Faza 3 PA PRE
24. Cum actioneaza Clasa IV pe Faza 0: Depolarizarea Spontana;
Frecventa Conducere AV; PA
25. In ce afectiuni se daBlocAdr:1. Hiper plazie Prostata, 2.
Hiperlipidemie26. Clase Laxative:1.Volum-MetilCeluloza,Plicarbophil
,
2.Emoliente-Docusat Cu/Na,
3.Lubr-Ol.Parafina/Magnezia
Usta,4.Iritante-Senna,fftaleina,Ol.castor,Ol.Ricin
5.Osmotice-MgSO4. Citrat. PolietilenGliolElectroliti = Fortrans,
Lactuloza -scade NH3 Encef. portala,
27. IndicatiiMgSO4:= laxative osmotice in constipatie, Atrag apa
= Bol Fecal
28. UG+HPClase: 1. Antisecr-IPP:Omepraz40, Lansopraz15-30,
Pantopraz40,2. BRH2:Cimet800Zi*No,Ranit*300,Famot*40,
3. Protectoare Bi525x3/zi,
4. Abo:Metro400x3/zi, Tinidazol, Claritro500x2/zi,
Amoxi500x3/zi
29. Boala Inf Int Clase
1 .5AminoSalicilati-Sulfasalozina,Mesalazina-Sulfapiridina4g.zi
in 4 prize initial500mgx2/zi,Similar Olsalazina. 2.GCz
Prednison40mg/zi,
3.ImmSupres:dc nu raspunde la
2Deriv.de.Tioguamina=6MercaptoPurina 1.5mg/kg/zi,
Azatiopurina2-2,5mg/kg/zi}3-6
luniMetotrexat15-25mg/sapt im:Debut Ac Mai rapid de cat
