Laporan Praktikum Metabolisme Lemak

8/20/2019 Laporan Praktikum Metabolisme Lemak

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LAPORAN PRAKTIKUM

PENGAMATAN BIOKIMIA GIZI“Metabolisme Lemak”

Dosen :

Rofiqi, ! T

Rat"i P#s$a"i%i, !&a"m! A$t

Disusun oleh :

'! et(a%i%)*(a+ -'./! et(o 0i*(a P! -/.1! iti &ai*at#l U! -1.-! Ul#l Ib"o+ B! --.2! 3ita &a*+ila+ -2.

Gelomba%) II Kelom$ok -.

A%)kata%4Kelas 5 '' 4 6I7B

UNIT PELAK ANA TEKNI 8INA KE E9ATANPRO3IN I :A0A TIMUR AKA8EMI GIZIURABA;A TA9UN PELA:ARAN /


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KATA PENGANTAR

e)ala $#>i *a% s(#k#" kami $a%>atka% ke$a*a T#+a% ;a%) Ma+a Esa,

ka"e%a atas be"kat *a% lim$a+a% "a+mat%(a, kami *a$at me%(elesaika% makala+

i%i *e%)a% te$at ?akt#! emo)a makala+ i%i *a$at *i$e")#%aka% seba)ai sala+

sat# $et#%>#k ba)i sel#"#+ ma+asis?a!

Makala+ i%i *is#s#% a)a" $a"a ma+asis?a *a$at mem$e"l#as Ilm# te%ta%)

Metabolisme Lemak, (a%) kami sa>ika% be"*asa"ka% be"ba)ai s#mbe" i%fo"masi

*a% melal#i $"aktik! emo)a makala+ i%i *a$at membe"ika% ?a?asa% (a%) lebi+

l#as *a% me%>a*i s#mba%)a% $emiki"a% ke$a*a $emba@a k+#s#s%(a $a"a

ma+asis?a Aka*emi Gi i #"aba(a!

Kami me%(a*a"i ba+?a makala+ i%i masi+ ba%(ak kek#"a%)a% *a% >a#+

*a"i sem$#"%a! Melal#i makala+ i%i kami me%)+a"a$ka% k"itik se"ta sa"a% *a"i

$a"a $emba@a! Kami memi%ta maaf a$abila a*a kek#"a%)a% *a% kesala+a% (a%)

te"*a$at *alam makala+ i%i!

8e%)a% i%i kami mem$e"semba+ka% makala+ i%i *e%)a% $e%#+ "asa

te"ima kasi+ *a% semo)a makala+ i%i *a$at membe"ika% ma%faat ba)i $a"a

ma+asis?a *a% $emba@a!

#"aba(a, /2 Oktobe" /


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DAFTAR ISI


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BAB I

PENDAHULUAN

'!' Lata" Belaka%)

Li$i* te"*a$at *alam maka%a% seba)ia% besa" be"#$a lemak! Pa*a

#m#m%(a li$i* me"#$aka% ko%*#kto" $a%as (a%) >elek, se+i%))a li$i*

*alam t#b#+ mem$#%(ai f#%)si #%t#k me%@e)a+ te">a*i%(a ke+ila%)a%

$a%as *a"i t#b#+! Maki% ba%(ak >#mla+ lemak, maki% baik f#%)si%(a

mem$e"ta+a%ka% $a%as *alam t#b#+! Pa*a $"oses oksi*asi ' )"am lemak me%)+asilka% e%e")i sebesa" kkal, se*a%)ka% ' )"am ka"bo+i*"at

ma#$#% $"otei% +a%(a me%)+asilka% - kkal! elai% it# lemak mem$#%(ai

f#%)si meli%*#%)i o")a%7o")a% t#b#+ te"te%t# *a"i ke"#saka% akibat

be%t#"a% ata# )o%@a%)a%!

Pe%@e"%aa% lemak te"#tama te">a*i *alam #s#s, ka"e%a *alam m#l#t *a%

lamb#%) ti*ak te"*a$at e% im li$ase (a%) *a$at me%)+i*"olisis lemak!

8alam #s#s, lemak *i#ba+ *alam be%t#k em#lsi, se+i%))a m#*a+

be"+#b#%)a% *e%)a% e% im stea$si% *alam @ai"a% $a%k"eas! 9asil ak+i"

$"oses $e%@e"%aa% lemak iala+ asam lemak, )lise"ol, mo%o)lise"i*a,

*i)lise"i*a se"ta sisa t"i)lise"i*a!

Pe%)el#a"a% @ai"a% $a%k"eas *i"a%)sa%) ole+ +o"mo% sek"eti% *a%

$a%k"eo imi%! ek"eti% me%i%)katka% >#mla+ elekt"olit *a% @ai"a%

$a%k"eas, se*a%)ka% $a%k"eoe% im me"a%)sa%) $e%)el#a"a% e% im7e% im

*alam @ai"a% $a%k"eas! Lemak (a%) kel#a" *a"i lamb#%) la%)s#%) mas#k ke*alam #s#s me"a%)sa%) $e%)el#a"a% +o"mo% kolesistoki% (a%) $a*a

)ili"a%%(a me%(ebabka% ka%t#%) em$e*# be"ko%t"aksi +i%))a

me%)el#a"ka% @ai"a% em$e*# ke*alam *#o*e%#m! Li$i* lai% (a%) *a$at

te"+i*"olisis ole+ @ai"a% $a%k"eas a%ta"a lai% a*ala+ lesiti% ole+

fosfoli$ase, fosfatase *a% este"aseC este" koleste"ol ole+ koleste"ol este"ase

*i+i*"olisis me%>a*i koleste"ol asam lemak! Abso"$si +asil $e%@e"%aa%

lemak seba)ia% besa" D< . a*ala+ asam lemak *a% seba)ia% la)i /< .


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mo%o)lise"i*a te">a*i $a*a #s#s ke@il! Pa*a ?akt# asam lemak *a%

mo%o)lise"i*a *iabsos"bsi melal#i sel7sel m#kosa $a*a *i%*i%) #s#s,

me"eka *i#ba+ kembali me%>a*i lemak ata# t"i)lise"i*a! Lemak (a%)

te">a*i i%i be"be%t#k $a"tikel ke@il (a%) *iseb#t kilomik"o% *a% *iba?a

ke*alam *a"a+ melal#i @ai"a% limfe!

Lemak mem$#%(ai bebe"a$a f#%)si ses#ai *e%)a% sifat7sifat (a%)

*imiliki lemak te"seb#t! Lemak *i$e"l#ka% ole+ t#b#+ ma%#sia a)a" *a$at

be"e*a" ke sel#"#+ t#b#+, maka *i$e"l#ka% s#at# alat t"a%s$o"t k+#s#s

(a%) *oseb#t li$o$"otei%! 8a"i bebe"a$a f"aksi li$o$"otei% (a%) be"a*a

*alam $lasma a*a (a%) mem$#%(ai sifat baik *a% >elek! 9al i%i *a$at

te">a*i ka"e%a a*a%(a $e"be*aa% kemam$#a% *i *alam ka%*#%)a%

se%(a?a (a%) *ia%)k#t%(a! eba)ai @o%to+ 98L me"#$aka% sala+ sat#

f"aksi li$o$"otei% $lasma (a%) mem$#%(ai sifat baik, ka"e%a mem$#%(ai

kemam$#a% $e%)a%)k#t koleste"ol *a"i >a"i%)a% eFt"a+e$a" me%#># ke

>a"i%)a% +e$a" (a%) sete"#s%(a koleste"ol *imetabolisme *a% *ikel#a"ka%

be"sama em$e*#! Koleste"ol me"#$aka% sala+ sat# se%(a?a (a%) bisa

me%imb#lka% at+e"os@le"osis (ait# a$abila te"timb#% *i *alam *i%*i%)

$emb#l#+ *a"a+! Pe%(akit (a%) se"i%) te">a*i akibat at+e"os@le"osis

ko"o%e" (a%) se"i%) *iseb#t $e%(akit >a%t#%) ko"o%e"! 8i I%*o%esia $a*a

ta+#% ' D/ $e%(akit P:K me%em$ati #"#ta% ke72 *a"i $e%(ebab kematia%,

kem#*ia% $a*a ta+#% ' < be")ese" me%em$ati #"#ta% ke71 *a% se>ak

ta+#% ' = me%>a*i #"#ta% ke7/!

P"oses *asa" (a%) me%(ebabka% P:K a*ala+ i%filt"asi lemak $a*a

a"t+e"i ko"o%a"ia (a%) *ike%al seba)ai at+e"os@le"osis! Lem$e%)at+e"os@le"osis timb#l *alam *i%*i%) a"te"i *alam, bebe"a$a $#l#+ ta+#%

sebel#m me%imb#lka% akibat )e>ala kli%is%(a a%ta"a lai% a%)i%a $e@to"is,

mioka"* i%fa"k, ata# kematia% me%*a*ak! &akto" "esiko (a%) be"+#b#%)a%

*e%)a% P:K a%ta"a lai% +i$e"li$i*emia, me"okok, +i$e"te%si, *iabetes

mellit#s, obesitas, k#"a%) aktifitas, ti$e ke$"iba*ia%, *a% st"ess! 8ia%ta"a

fa@to" "esiko te"seb#t kem#%)ki%a% +i$e"li$i*emia ata#

+i$e"koleste"olemia me"#$aka% fakto" te"$e%ti%)! e@a"a t"a*isio%al total


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koleste"ol $lasma *a% li$o$"otei% s$esifik *i)#%aka% #%t#k me%ilai "esiko

at+e"os@le"osis, ka*a" koleste"ol, L8L be"+#b#%)a% la%)s#%) *e%)a%

"esiko, se*a%)ka% 98L be"ba%*i%) te"balik!

Ti)a kom$o%e% #tama li$o$"otei% a*ala+ koleste"ol, t"i)lise"i*a,

*a% fosfoli$i*! 8#a f"aksi li$o$"otei% (ait# alfa H., li$o$"otei% 98L.,

*a% beta ., li$o$"otei% *e%sitas "e%*a+ kilomik"o%, 3L8L, L8L. *a$at

*i$isa+ka% *e%)a% elekt"ofo"esis! Kelom$ok a*ala+ @o%t"ib#to" #tama

te">a*i%(a a"t+e"ios@le"osis *a% $e%(akit a"te"i ko"o%e"! Kelom$ok H (ait#

98L. *iseb#t lemak baik (a%) te"*i"i *a"i 2< $"otei% *a% memba%t#

me%)#"a%)i $e%imb#%a% $laq#e *alam $emb#l#+ *a"a+!

1.2 Tujuan

T#>#a% *a"i $"aktik#m i%i a*ala+ *i+a"a$ka% ma+asis?a mam$#5

'! Ma+asis?a +a"#s *a$at me%)eta+#i te%ta%) metabolisme lemak!/! Ma+asis?a +a"#s me%)eta+#i *a% me%)amati $a*a $eme"iksaa%

ko%se%t"asi total li$i*, koleste"ol, t"i)lise"i*a, 98L, *a% L8L

koleste"ol!1! Ma+asis?a +a"#s me%)eta+#i *a% me%)amati $eme"iksaa%

mak"osko$ik li$o$"otei%!

1. !an"aa#

Ma%faat *a"i $"aktik#m i%i a*ala+ *i+a"a$ka% ma+asis?a mam$#5

'! Ma%faat Teo"itis5

9asil $eme"iksaa% *a% $e%)amata% i%i *i+a"a$ka% *a$at

be")#%a ba)i $e%)emba%)a% ilm# $e%)eta+#a%, te"#tama te"kait

*e%)a% s$esime% *e%)a% $e%(akit *isli$i*emia *a% $e%(akit

metabolisme lai%%(a!

/! Ma%faat P"aktis5a! Peme"iksaa% i%i *i+a"a$ka% *a$at membe"i ma%faat *a% i%fo"masi

ke$a*a $et#)as kese+ata% *alam "a%)ka me%@e)a+ *a%

me%a%))#la%)i $e%(akit *isli$i*emia *a% $e%(akit metabolisme

lai%%(a!


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b! Ba)i mas(a"akat, $e%elitia% i%i *a$at membe"ika% i%fo"masi

te%ta%) "esiko $e%(akit *isli$i*emia *a% $e%(akit metabolisme

lai%%(a!

@! Ba)i $e%eliti, $e%elitia% i%i be"ma%faat seba)ai sa"a%a #%t#k bela>a" be"fiki" k"itis *alam me%)emba%)ka% ilm# $e%)eta+#a%

*a% me%)a$likasika% teo"i7teo"i (a%) *i$ela>a"i *i ba%)k# k#lia+!

1! Ma+asis?a *i+a"a$ka% mam$# me%)eta+#i ka%*#%)a% *alam

metabolisme lemak!-! Ma+asis?a +a"#s mam$# me%e"a$ka% $"oses $e%)ambila% total li$i*

*a% kolest"ol!2! Ma+asis?a +a"#s mam$# me%)eta+#i $e"+it#%)a% total li$i* *a%

kolest"ol!


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BAB II

TIN$AUAN PUSTAKA

Li$i* a*ala+ setia$ kelom$ok +ete"o)e% lemak *a% s#bsta%si

se"#$a lemak, te"mas#k asam lemak, lemak %et"al, lili%, *a% ste"oi*, (a%)

be"sifat la"#t *alam ai" *a% la"#t *alam $ela"#t %o%$ola"! Li$i*, (a%)

m#*a+ *isim$a% *alam t#b#+, be"f#%)si seba)ai s#mbe" ba+a% baka",

me"#$aka% ba+a% (a%) te"$e%ti%) *alam st"#kt#" sel *a% mem$#%(ai

f#%)si biolo)ik (a%) lai%! Li$i* *ia%)k#t *i *alam $lasma *a"a+ seba)ai

li$o$"otei%! 9asil ekst"aksi se%(a?a li$i* $lasma *e%)a% $ela"#t li$i*

(a%) ses#ai aka% mem$e"li+atka% em$at kelom$ok #tama li$i* (a%)

te"*a$at *i *alam li$o$"otei%! Keem$at se%(a?a it# (ait# t"iasil)lise"ol,

fosfoli$i*, koleste"ol, *a% este" koleste"il! Te"*a$at $#la f"aksi asam lemak

"a%tai7$a%>a%) (a%) ti*ak te"este"ifikasi (a%) *iseb#t asam lemak bebas

f"ee fatt( a@i*., li$i* $lasma i%i se@a"a metabolik (a%) $ali%) aktif!

8i sam$i%) asam lemak bebas, a*a em$at kelom$ok #tama

li$o$"otei% (a%) tela+ *ii*e%tifikasi keem$at kelom$ok li$o$"otei% i%i

mem$#%(ai mak%a (a%) $e%ti%) se@a"a fisiolo)is *a% #%t#k *ia)%osis

kli%is! Keem$at kelom$ok i%i a*ala+ '. kilomik"o% (a%) be"asal *a"i

$e%(e"a$a% t"iasil)lise"ol *i #s#sC /. li$o$"otei% *e%)a% *e%sitas (a%)

sa%)at "e%*a+ ata# Je"( lo? *e%sit( li$o$"otei% 3L8L ata# $"e7 7

li$o$"otei%. (a%) be"asal *a"i +ati #%t#k me%)el#a"ka% t"iasil)lise"olC 1.

li$o$"otei% *e%)a% *e%sitas "e%*a+ ata# lo? *e%sit( li$o$"otei% L8L ata#

7li$o$"otei%. (a%) mem$e"li+atka% ta+a$ ak+i" *i *alam katabolisme

3L8LC *a% -. li$o$"otei% *e%)a% *e%sitas ti%))i ata# +i)+ *e%sit(

li$o$"otei% 98L ata# H7li$o$"otei%. (a%) te"libat *alam metabolisme

3L8L *a% kilomik"o% se"ta $e%)a%)k#ta% koleste"ol! T"iasil)lise"ol

me"#$aka% #%s#" li$i* (a%) *omi%a% $a*a kilomik"o% *a% 3L8L,

se*a%)ka% koleste"ol *a% fosfoli$i* masi%)7masi%) *omi%a% $a*a L8L

*a% 98L!


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$enis%jenis Koles#e&ol 'Ka(a& No&)al*

a! Koleste"ol memiliki ka*a" (ait# %o"mal /


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Pe%i%)kata% ka*a" li$o$"otei%, te"#tama koleste"ol L8L, se>ala%

*e%)a% be"tamba+%(a #sia! 8alam kea*aa% %o"mal, $"ia memiliki ka*a"

(a%) lebi+ ti%))i, teta$i setela+ me%o$a#se ka*a"%(a $a*a ?a%ita m#lai

me%i%)kat! &akto" lai% (a%) me%(ebabka% ti%))i%(a ka*a" lemak te"te%t#

misal%(a 3L8L *a% L8L. a*ala+ "i?a(at kel#a")a *e%)a% *isli$i*emia,

obesitas, *iet ti%))i lemak, k#"a%) melak#ka% ola+"a)a, $e%))#%aa%

alko+ol, me"okok, *iabetes (a%) ti*ak te"ko%t"ol *e%)a% baik, *a% kele%>a"

ti"oi* (a%) k#"a%) aktif! Pemb#a%)a% lemak *a"i *a"a+ $a*a setia$ o"a%)

memiliki ke@e$ata% (a%) be"be*a! eseo"a%) bisa maka% se>#mla+ besa"

lemak +e?a%i *a% ti*ak $e"%a+ memiliki ka*a" koleste"ol total lebi+ *a"i

/ala%i *iet "e%*a+ lemak (a%)

ketat *a% ti*ak $e"%a+ memiliki ka*a" koleste"ol total *iba?a+ /=< m)4*L!

Pe"be*aa% i%i tam$ak%(a be"sifat )e%etik *a% se@a"a l#as be"+#b#%)a%

*e%)a% $e"be*aa% ke@e$ata% mas#k *a% kel#a"%(a li$o$"otei% *a"i ali"a%

*a"a+!

Ko)+li,asi Disli+i(e)iaA$abila *isli$i*emia ti*ak se)e"a *iatasi, maka *a$at te">a*i

be"ba)ai ma@am kom$likasi, a%ta"a lai% at+e"oskle"osis, $e%(akit >a%t#%)

ko"o%e", $e%(akit se"eb"oJask#la" se$e"ti st"ok, kelai%a% $emb#l#+ *a"a+

t#b#+ lai%%(a, *a% $a%k"eatitis ak#t! In"a&, !io,a&( A,u#

I%fa"k Mioka"* Ak#t IMA. me"#$aka% )a%))#a% ali"a% *a"a+ ke

>a%t#%) (a%) me%(ebabka% sel otot >a%t#%) mati! Ali"a% *a"a+ *i

$emb#l#+ *a"a+ te"+e%ti setela+ te">a*i s#mbata% ko"o%e" ak#t, ke@#ali

se>#mla+ ke@il ali"a% kolate"al *a"i $emb#l#+ *a"a+ *i sekita"%(a! 8ae"a+

otot *i sekita"%(a (a%) sama sekali ti*ak me%*a$at ali"a% *a"a+ ata#

ali"a%%(a sa%)at se*ikit se+i%))a ti*ak *a$at mem$e"ta+a%ka% f#%)si otot

>a%t#%), *ikataka% me%)alami i%fa"k! Istila+ i%fa"k mioka"* ak#t

se+a"#s%(a *i)#%aka% ketika te"*a$at b#kti a*a%(a %ek"osis mioka"*ial

$a*a iskemik mioka"* ak#t! 8e%)a% ko%*isi te"seb#t, sala+ sat# *a"i

k"ite"ia be"ik#t meme%#+i *ia)%osis #%t#k i%fa"k mioka"*5


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'! 8eteksi ke%aika% *a%4ata# t#"#%%(a %ilai bioma"ke" >a%t#%) sebaik%(a

t"o$o%i% >a%t#%) @T%. *a% meme%#+i sala+ sat# k"ite"ia be"ik#t5

a! Ge>ala iskemia

b! Pe"#ba+a% (a%) si)%ifika% )elomba%) T7se)me%7T T7T. ata#

blok @aba%) be"kas ki"i Left B#%*le B"a%@+ Blo@k4LBBB.!

@! Gelomba%) Q $atolo)is $a*a EKG

*! Pe%@it"aa% (a%) memb#ktika% kematia% mioka"*i#m ata#

kelai%a% )e"ak *i%*i%) "e)io%al!

e! I*e%tifikasi s#at# t"omb#s i%t"a ko"o%e" *e%)a% a%)io)"afi ata#

oto$si!

/! Kematia% >a%t#%) *e%)a% )e>ala s#)estif *a"i iskemia mioka"* *a%

$e"#ba+a% EKG $a*a iskemik mioka"* ata# LBBB (a%) ba"#!

1! I%te"Je%si ko"o%e" $e"k#ta% Pe"@#ta%eo#s @o"o%a"( i%te"Je%tio%4P I.

te"kait i%fa"k mioka"*!

-! te%t t"ombosis te"kait *e%)a% i%fa"k mioka"* ketika *i*eteksi *e%)a%

a%)io)"afi ko"o%e" ata# oto$si $a*a iskemia mioka"* *a% *e%)a% ke%aika%

*a%4ata# t#"#%%(a %ilai bioma"ke" >a%t#%)!

2! o"o%a"( a"te"( b($ass )"afti%) ABG. te"kait i%fa"k mioka"* *e%)a%

k"ite"ia $e%i%)kata% %ilai bioma"ke" >a%t#%)!

Klasi"i,asi In"a&, !io,a&( A,u#

I%fa"k Mioka"* Ak#t *iklasifikasika% be"*asa" EKG '/ sa%*a$a%

me%>a*i5 '! I%fa"k mioka"* ak#t T7eleJasi TEMI. 5 okl#si total *a"i

a"te"i ko"o%e" (a%) me%(ebabka% a"ea i%fa"k (a%) lebi+ l#as meli$#ti

sel#"#+ ketebala% mioka"*i#m, (a%) *ita%*ai *e%)a% a*a%(a eleJasi

se)me% T $a*a EKG! /! I%fa"k mioka"* ak#t %o% T7eleJasi N TEMI. 5

okl#si seba)ia% *a"i a"te"i ko"o%e" ta%$a melibatka% sel#"#+ ketebala%

mioka"*i#m, se+i%))a ti*ak a*a eleJasi se)me% T $a*a EKG!


12/30

Fa,#o& Risi,o In"a&, !io,a&( A,u#0a%ita me%)alami i%fa"k mioka"* ak#t $e"tama me"eka "ata7"ata

ta+#% kem#*ia% *iba%*i%) $"ia! &akto"7fakto" "isiko (a%) *a$at

*imo*ifikasi se@a"a si)%ifika% be"+#b#%)a% *e%)a% i%fa"k mioka"* ak#t5'! Li$i* ab%o"mal *i*efi%isika% *e%)a% me%))#%aka% "asio a$oB 4 a$oA!/! Pe"okok 1! Obesitas ab*omi%al-! 9i$e"te%si2! 8iabetes melit#s=! AktiJitas fisik (a%) k#"a%)D! Pe%))#%aa% alko+ol se@a"a te"at#" *i*efi%isika% seba)ai ko%s#msi

alko+ol seti*ak%(a ti)a kali semi%))#!! 8iet be"isiko

! &akto" st"es $sikososial

Gejala (an Tan(a In"a&, !io,a&( A,u#Gamba"a% kli%is i%fa"k mioka"* #m#m%(a be"#$a %(e"i *a*a

s#bste"%#m (a%) te"asa be"at, me%eka%, se$e"ti *i"emas7"emas *a%

te"ka*a%) *i>ala"ka% ke le+e", "a+a%), e$i)ast"i#m, ba+#, ata# le%)a% ki"i,

ata# +a%(a "asa ti*ak e%ak *i *a*a! I%fa"k mioka"* ak#t se"i%) *i*a+#l#i

ole+ se"a%)a% a%)i%a $ekto"is $a*a sekita" 2< $asie%! Nam#%, %(e"i

$a*a $e%(akit i%i biasa%(a be"la%)s#%) bebe"a$a >am sam$ai +a"i, >a"a%)a*a +#b#%)a%%(a *e%)a% aktiJitas fisik *a% biasa%(a ti*ak ba%(ak

be"k#"a%) *e%)a% $embe"ia% %it"o)lise"i%, %a*i biasa%(a @e$at *a% lema+,

$asie% >#)a se"i%) me%)alami *iafo"esis! Pa*a seba)ia% ke@il $asie% /<

sam$ai 1< . i%fa"k mioka"* ak#t ti*ak me%imb#lka% %(e"i *a*a! ile%t

A@#te M(o@a"*ial I%fa"@tio% i%i te"#tama te">a*i $a*a $asie% *e%)a%

*iabetes mellit#s *a% +i$e"te%si se"ta $a*a $asie% be"#sia la%>#t!


13/30

BAB III

!ET-DE PENGA!ATAN

.1 a,#u (an Te)+a# Pen/a)a#an

P"aktik#m $e%)amata% Metabolisme Lemak i%i be"la%)s#%) $a*a+a"i elasa, /< Oktobe" /. P&o(esu& Ke&ja


14/30

1!1!' P&ose(u& Ke&ja Ka(a& Koles#e&ol

'! ia$ka% tab#%) "eaksi *a% melak#ka% la%)ka+7la%)ka+ be"ik#t5

Bahan Blan,o Sa)+el0S#an(a&ta%*a" am$el

Aq#a*estRea)e%t

77

'< SL'


15/30

MiF 5 I%k#basi '2 Ba@a $a*a λ 2


16/30

BAB I

HASIL KER$A

.1 Hasil Pen/a)a#an (an Pe)e&i,saan Ka(a& Koles#e&ol (an T&i/lise&i(a1. Hasil sa)+el (a&ah ,elo)+o, ,a)i 'Kelo)+o, * )en//una,an

sa)+el (a&ah ' i#a*:

Penen#uan Ka(a& Koles#e&ol

8iketa+#i 5 %ilai AB am$el


17/30

'2


18/30

L8L Total Koleste"ol 7 98L

'== 7 --

'//. Hasil sa)+el (a&ah 'Kelo)+o, * )en//una,an sa)+el (a&ah

'Re4a*:

Penen#uan Ka(a& Koles#e&ol

8iketa+#i 5 %ilai AB am$el


19/30


20/30

5.1 Pe)6ahasan Hasil Pen/a)a#an Keselu&uhan Kelo)+o,

P"aktik#m metabolisme lemak i%i *i?a>ibka% #%t#k be"$#asa

te"lebi+ *a+#l#, ka"e%a #%t#k me%)eta+#i metabolisme lemak (a%)ses#%))#+%(a *alam t#b#+! P"aktik#m biokimia i%i *i?a>ibka%me%)ko%s#msi maka%a%7maka%a% (a%) s#*a+ *ite%t#ka% *a% *iketa+#i

$e"be*aa% a%ta"a o"a%) *e%)a% sam$el me%# le%)ka$ *e%)a% sa(#" ta%$a b#a+ *a% o"a%) *e%)a% sam$el me%# le%)ka$ *e%)a% b#a+ ta%$a sa(#"!

'! Pe%)amata% *a% $eme"iksaa% kelom$ok ' $a*a NoJias. (a%)me%)ko%s#msi maka%a% me%# le%)ka$ *e%)a% b#a+ ta%$a sa(#" *i+asilka% $e%)#>ia% ka*a" li$o$"otei% e% imatis. $a*a Koleste"ol

a*ala+ '2

$eme"iksaa% stik%(a, *a$at te">a*i $a*a keaa*aa% bate"ai! :ika *ili+at


21/30

$a*a ka*a" koleste"ol e% imatis. *i+asilka% (ait# '== %o"mal. ka"e%a batas %o"mal /ala% %o"mal meski$#% ka*a" L8L%(a se*ikit

be"lebi+! 9al i%i *ika"e%aka% te"*a$at fakto" be"at ba*a% (a%) be"lebi+! es#ai *e%)a% lite"at#"e (a%) a*a >ika ko%se%t"asi ka*a" 98L*a% L8L ti*ak seimba%), maka $e%(ebab (a%) $ali%) se"i%) a*ala+o"a%) *e%)a% be"at ba*a% lebi+ obesitas., k#"a%) ola+"a)a (a%) "#ti%,k#"a%)%(a maka% sa(#" *a% b#a+ (a%) be"se"at ti%))i *a%)me%)a%*#%) 3itami% !

1! Pe%)amata% *a% $eme"iksaa% kelom$ok 1 $a*a Re a. (a%)me%)ko%s#msi maka%a% me%# le%)ka$ *e%)a% b#a+ ta%$a sa(#" *i+asilka% $e%)#>ia% ka*a" li$o$"otei% e% imatis. $a*a Koleste"ola*ala+ ''


22/30

-! Pe%)amata% *a% $eme"iksaa% kelom$ok - $a*a 3ita. (a%)me%)ko%s#msi maka%a% me%# le%)ka$ *e%)a% sa(#" ta%$a b#a+*i+asilka% $e%)#>ia% ka*a" li$o$"otei% e% imatis. $a*a Koleste"ola*ala+ '2D, D, T"i)lise"i*a DD,=#"ka% #%t#k me%)ko%s#msi maka%a% me%# le%)ka$*e%)a% b#a+ ta%$a sa(#" selama / >am! etela+ / >am *i$e"ole+ ka*a" koleste"ol ses#*a+ maka%. (ait# ' ! :ika *isim$#lka% ka*a" koleste"ol %aik $a*a $eme"iksaa% stik sebel#m *a% ses#*a+ (ait# ' 1

' ! 9al i%i %o"mal ka"e%a t#b#+ s#*a+ *ibe"i as#$a% maka%a%se+i%))a ka*a" koleste"ol%(a %aik! :ika *ili+at $a*a ka*a" koleste"ol

e% imatis. *i+asilka% (ait# '2D, D %o"mal. ka"e%a batas %o"mal /ala% ti*ak %o"mal ka"e%a a*a te">a*i%(aketi*akseimba%)a% $a*a ka*a" 98L *e%)a% L8L! 9al i%i *ika"e%aka%te"*a$at fakto" be"at ba*a% (a%) be"lebi+! es#ai *e%)a% lite"at#"e

(a%) a*a >ika ko%se%t"asi ka*a" 98L *a% L8L ti*ak seimba%), maka $e%(ebab (a%) $ali%) se"i%) a*ala+ o"a%) *e%)a% be"at ba*a% lebi+obesitas., k#"a%) ola+"a)a (a%) "#ti%, k#"a%)%(a maka% sa(#" *a%

b#a+ (a%) be"se"at ti%))i *a%) me%)a%*#%) 3itami% !

2! Pe%)amata% *a% $eme"iksaa% kelom$ok 2 $a*a alma. (a%)me%)ko%s#msi maka%a% me%# le%)ka$ *e%)a% sa(#" ta%$a b#a+*i+asilka% $e%)#>ia% ka*a" li$o$"otei% e% imatis. $a*a Koleste"ola*ala+ '/1,2', T"i)lise"i*a D',/2, 98L = , *a% L8L 22,2'!Peme"iksaa% sela%>#t%(a me%))#%aka% stik (a%) me%)+asilka% ka*a"

koleste"ol sebel#m maka%. (ait# '2 ! etela+ $eme"iksaa% ta+a$ $e"tama, *ia%>#"ka% #%t#k me%)ko%s#msi maka%a% me%# le%)ka$*e%)a% b#a+ ta%$a sa(#" selama / >am! etela+ / >am *i$e"ole+ ka*a" koleste"ol ses#*a+ maka%. (ait# ' -! :ika *isim$#lka% ka*a" koleste"ol %aik $a*a $eme"iksaa% stik sebel#m *a% ses#*a+ (ait# '2

' -! 9al i%i %o"mal ka"e%a t#b#+ s#*a+ *ibe"i as#$a% maka%a%se+i%))a ka*a" koleste"ol%(a %aik! :ika *ili+at $a*a ka*a" koleste"ol

e% imatis. *i+asilka% (ait# '/1,2' %o"mal. ka"e%a batas %o"mal /


23/30

%o"mal. ka"e%a batas %o"mal a%ta"a -< =< m)4*l *a% =< m)4*l!Pa*a ka*a" L8L *i+asilka% (ait# 22,2' %o"mal. ka"e%a batas %o"mala%ta"a 'ala% %o"mal!


24/30

BAB I

PENUTUP

5.1 Kesi)+ulan

Kesim$#la% (a%) *i*a$at *a"i +asil $"aktik#m i%i a*ala+5

'! Pa*a $eme"iksaa% metabolisme lemak setia$ kelom$ok *i+asilka%ka*a" li$o$"otei% (a%) be"be*a7be*a! 9asil i%i te")a%t#%) $a*ametabolisme setia$ i%*iJi*#! :ika seseo"a%) memiliki be"at ba*a% (a%)

be"lebi+ maka "esiko ko%se%t"asi metabolisme lemak *alam t#b#+%(aaka% te">a*i keti*akseimba%)a%! 9al i%i *ika"e%aka% te"*a$at ba%(ak fakto" (ait# be"at ba*a% (a%) sa%)at be"lebi+ obesitas., k#"a%)%(ame%)o%t"ol as#$a% maka%a% (a%) me%)a%*#%) at )i i baik, se"i%)me%)o%s#msi maka%a% (a%) memiliki ka*a" lemak ti%))i*iba%*i%)ka% se"at, k#"a%)%(a maka% sa(#" (a%) ti%))i se"at,k#"a%)%(a maka% b#a+ (a%) me%)a%*#%) 3itami% , *a% ti*ak $e"%a+"#ti% ola+"a)a!

/! Pe%ti%)%(a $eme"iksaa% *a% $"aktik#m i%i a*ala+ #%t#k me%)eta+#i $a*a masi%)7masi%) $e"?akila% kelom$ok ka*a" s#at# metabolismelemak *alam t#b#+! P"aktik#m be"ma%faat ka"e%a kita *a$at lebi+me%)eta+#i sebe"a$a ka*a" %o"mal li$o$"otei% (a%) te"*a$at *alamt#b#+! elai% it#, $e%)amata% i%i >#)a #%t#k me%)eta+#i sebe"a$a"esiko >ika te">a*i keti*akseimba%)a% metabolisme lemak *alam t#b#+!

5.2 Sa&an

eba)ai a+li )i i %a%ti%(a kita *it#%t#t +a"#s me%)eta+#i ma%faatmaka%a% (a%) be")i i *a% maka%a% (a%) k#"a%) )i i *e%)a%me%)+#b#%)ka% "esiko te"+a*a$ $e%(akit! ela%>#t%(a kita *a$atmembe"ika% $e%*i*ika% te%ta%) maka%a% (a%) be"%ilai )i i lebi+ ke$a*amas(a"akat, a)a" mas(a"akat *a$at me%>a*i ta+# $e%ti%)%(a ma%faatmaka%a% (a%) memiliki at )i i ba)i t#b#+! e+i%))a *ikem#*ia% +a"i

$e%(akit *e)e%e"atif *a$at *i@e)a+ *a% kese+ata% mas(a"akat me%>a*ise+at!


25/30

DAFTAR PUSTAKA

Rofiqi! /


26/30

La)+i&an

No.

Ga)6a& Ke#e&an/an

'! Me%)ambil sam$el *a"a+ *i $emb#l#+ Je%a me%))#%aka% >a"#m s#%tik!

/! Me%)ambil sam$el *a"a+ $a*a $eme"iksaa% sti@k!


27/30

1! am$el *a"a+ (a%) s#*a+ *ise%t"if#)e!

-! 9asil $eme"iksaa% ka*a" koleste"ol

sebel#m maka%. *e%)a%me%))#%aka% sti@k!

2! 9asil $eme"iksaa% ka*a" koleste"olsebel#m maka%. *e%)a%

me%))#%aka% sti@k!


28/30

=! am$el *a"a+ *a"i masi%)7masi%)kelom$ok!

D! 9asil $e%e%t#a% koleste"ol (a%)tela+ *i+i*"olisis e% imatik *a%oksi*asi!

! 9asil $e%e%t#a% ka*a" 98L *a%L8L *e%)a% me%))#%aka%

$e"eaksi ko%se%t"asi totalKoleste"ol, ko%se%t"asi 98L,ko%se%t"asi TG!


29/30

! 9asil $e%e%t#a% koleste"ol *a%T"i)lise"i*a (a%) tela+ *i+i*"olisise% imatik *a% oksi*asi!

'

''! 9asil ka*a" T"i)lise"i*a $a*a $e%)ambila% sam$el *a"a+ *i $emb#l#+ Je%a *e%)a%me%))#%aka% s$ekt"ofotomete"!


30/30

'/! 9asil ka*a" Koleste"ol $a*a $e%)ambila% sam$el *a"a+ *i $emb#l#+ Je%a *e%)a%me%))#%aka% s$ekt"ofotomete"!

Documents

Laporan Praktikum Metabolisme Lemak