10 Second Case Studies

Round 2: Degenerative Neurological Conditions

PATIENT 1

• 55 years old male• Lateralized left-side muscle weakness• Dysphagia (difficulty swallowing)• Progressive difficulties with breathing• No familial history of similar symptoms

• Your diagnosis?• A) ALS (amyotrophic lateral sclerosis)• B) MD (muscular dystrophy)• C) MS (multiple sclerosis)• D) PD (Parkinson’s disease)

Patient 2

• 65 year old female• Anosmia• Rigidity localized to left foot• Pronounced resting tremor• No familial history of similar symptoms

• Your diagnosis?• A) ALS (amyotrophic lateral sclerosis)• B) MD (muscular dystrophy)• C) MS (multiple sclerosis)• D) PD (Parkinson’s disease)

Patient 3

• 2 year old male• Profound deafness• Progressive loss of reflex response and muscle tone• Red spot in macula• Familial history of similar symptoms

• Your diagnosis?• A) ALS (amyotrophic lateral sclerosis)• B) MD (muscular dystrophy)• C) Tay-Sach’s Disease• D) PD (Parkinson’s disease)

Patient 4• 30 year old female• Currently experiencing parathesia (numbness in extremities)• Previous parathesic episodes with intervening remission of

symptoms at age 22• Dysarthria (difficulty articulating speech) with similar remission of

symptoms at age 25• No familial history of similar symptoms

• Your diagnosis?• A) Tay-Sachs Disease• B) MD (muscular dystrophy)• C) MS (multiple sclerosis)• D) PD (Parkinson’s disease)

Patient 5

• 15 year old male• Obese• Experiencing joint and calf muscle pain• EKG and MRI show evidence of cardiomyopathy• Familial symptoms in male relatives

• Your diagnosis?• A) ALS (amyotrophic lateral sclerosis)• B) MD (muscular dystrophy)• C) MS (multiple sclerosis)• D) PD (Parkinson’s disease)