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Faculty of MedicineFaculty of MedicineAin Shams UniversityAin Shams University
Postgraduate StudiesPostgraduate Studies
Master of Science in Medical Biochemistry and Molecular Biology
في الماجستير و درجة الطبية الحيوية الكيمياء الجزيئية البيولوجيا
Program Code: BM600
Program Guide and Logbook
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TABLE OF CONTENTS:Page
I – Welcome StatementII - Mission StatementIII – Senior supervisor and affiliated departments and HospitalsIV – Program specifications 1 - Basic Information 2 - Professional Information 3 – Academic standards 4 – Curriculum structure and contents 5 - Program courses: 6. Program admission requirements: 7. Regulation for progression and program completion 8. Appendix: course specifications:Immunology course specificationPhrmacology course specificationPhysiology course specificationPractical Biochemistry courses pecificationMedical Biochemistry course specificationsMolecular Biology course specificationsBioinformatics course specificationsStatistics course specifications
V - General information
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VI – Your log book 1 – Introduction 2 – Supervisors 3 - Tables for training records 4 – Log book previewVII - Head of department approval for the exam entry
Detachable forms:
VIII -Thesis follow up IX - Evaluation forms
I – Welcome Statement:The Department of Medical Biochemistry and Molecular Biology welcomes
you to the Degree of Master of science in Medical Biochemistry and Molecular Biology. As a department we are committed to medical student education and continuously strive to improve your educational experience.
This handbook presents information guide and logbook activity of this master degree administered by Medical Biochemistry and Molecular Biology Department, Faculty of Medicine, Ain Shams University.
II - Mission Statement:The mission of the Faculty of Medicine, Ain Shams University is
• The preparation of a competent graduate, who is able to compete on both national and regional levels, capable of life long learning, training and tutoring, while adhering to the codes of practice of medical health services and ethics.
• The college as well, seeks continuous development of programs and courses. It also enhances expansion of applied scientific research and health programs for community services and environmental development.
The mission of this degree is:
To provide postgraduate students with a basic understanding of the biological processes in humans at a molecular level and to correlate any molecular defect or abnormality to medical problems
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To provide postgraduate students with advanced information concerning human genetics and the future of diagnostic and therapeutic tools.
To equip the students with preliminary knowledge and skills necessary for Biochemistry research
To provide the environment necessary to develop skills in self-evaluation, self-directed learning and critical appraisal enabling the medical biochemist to adapt to the rapid progress of information and changes that will occur in the profession throughout their careers.
III – Senior Supervisor and A ffilated Departments and Hospitals
Senior Supervisor
Prof.---------------------------------------------------------------------------------------------E-mail:
A ffilated Departments and Hospitals
Department of Medical Biochemistry and Molecular Biology, Faculty of Medicine, Ain Shams University.
IV – Program SpecificationsA- Basic Information1. Program title:
Master of science in Medical Biochemistry and Molecular Biology2. Progm type:
Single Double Multiple3. Faculty
Ain Shams University – Faculty of medicine4. Department Medical Biochemistry and Molecular Biology 5. Assistant coordinator: Professor Samar Kamal Kasim Professor of Medical Biochemistry and Molecular Biology 6. Coordinator:
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Professor Noura Elkholy Professor of Medical Biochemistry and Molecular Biology
7. Last date of program approval: July 2009
B- Professional Information:1. Program aims:To provide postgraduate students with a basic understanding of the biological processes in humans at a molecular level and to correlate any molecular defect or abnormality to medical problems
To provide postgraduate students with advanced information concerning human genetics and the future of diagnostic and therapeutic tools.
To provide the environment necessary to develop skills in self-evaluation, self-directed learning and critical appraisal enabling the medical biochemist to adapt to the rapid progress of information and changes that will occur in the profession throughout their careers.
To provide the postgraduate students with the opportunity to become competent medical biochemists with the skills required for a professional of medical biochemistry laboratory.
2. Intended learning outcomes (ILOs):a. Knowledge and understanding:By the end of this program the student should be able to:
a1- Describe the structure function relationship of some important proteins: hemoglobin, myoglobin, skeletal muscles, collagen, and immunoglobulins.
a2- Explain the methods of classification and regulation of enzymes as well as kinetics of enzymes and coenzymes. a3- Describe the structure of DNA and RNA as well as the processes of replication, transcription, translation, regulation of gene expression, and methods of in vivo and in vitro amplification of DNA.
a4- State the characteristics of the genetic code and the relation of various types of mutations to genetic diseases and cancers. a5- Describe the biochemical basis of cancer, gene therapy, stem cell therapy, and various techniques of genetic testing.
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a6- Describe the structure of biological membranes and classify the different mechanisms of signal transduction across membranes
a7- Describe the metabolic pathways of carbohydrates, lipids, and proteins, their energetics, their sites, the ways of their regulation and possible metabolic errors.
a8- Describe the components of mitochondrial ETC and their inhibitors. a9- Describe the composition of blood and explain the mechanism of blood clotting, anticoagulation and fibrinolysis.
b-Intellectual Skills: By the end of the course, students should be able to: b1- Integrate basic biochemical facts with clinical diseases.b2- Analyse and interpret different spectrophotometric data and use them in diagnosis of a clinical case. b3- Interpret the results of molecular biology techniques. b4- Identify electrophoretic bands, interpret disease-associated changes in plasma proteins and diagnose sickle cell trait and sickle cell anemia b5- Retrieve and analyze nucleic acids and proteins data (bioinformatics)b6- Differtiate between inherited and aquired hypercoagulable states b7- Solve any subject-related problems provided by staffb8- analyze laboratory data using statistical rules.
a- Professional and Practical Skills: By the end of the course, students should be able to:
c1- Prepare solutions of acids, bases, and buffers and adjust their concentration and pH c2- Use spectrophotometric assay methods to determine the concentration of substances in biological fluidsc3- Extract DNA, amplify a certain sequence of DNA by PCR and interpret results of DNA fingerprintingc4- Prepare buffers and make dilutions of known concentration.c5- Purify proteins by molecular sieving, by ion exchange or affinity chromatography and check protein purity.c6- Perform different types of assays as ELISA, immunodiffusion.c7- Perform different types of electrophoretic techniques.
d- General and Transferable Skills: By the end of the course, students should be able to: d1- Work in a team in the lab and cooperate with their colleagues and staff.
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d2- Use basic computing skills and internet to fulfill problem-based learning d3- Communicate relevant information with teaching staff and colleaguesd4- Recognize and effectively deal with unethical behavior of other members of lab team.d5-Understand the importance of life-long self-learning and show a strong commitment to it.
3. Academic standards: (Benchmarks)Academic reference standards guided by University of Vermont, Burlington, USA, Graduate College, Department of Biochemistry Contact Email: E-mail:[email protected]
Website: http://www.uvm.edu
4. Curriculum structure and contents:4 a- Program duration: two years (4 semesters)4b- Program structure:
المناهج
الدراسية الكودالمقرراتالساع
اتالمعتمدة
متطلباتالعلمي الكلية البحث أساسيات دورة
األول الجزء أو–الفسيولوجى أو–البكتريا BM60014 االدوية
الكيمياء فى عملية تدريبية فترةBM60022الحيوية
6الرسالة
الثاني الجزءالطبية الحيوية BM600312الكيمياء
الجزيئية BM60043البيولوجياتطبيقية و عملية BM60052دراسة
المقرراتاالختيارية
من : واحدة مادة الطالب يختار E6009 اإلحصاء -
معلوماتية طبت– البيو E6018يقاتE6009E60181
كراسة6األنشطة
9
36المجموع
5. Program courses:
a. CompulsoryCode Course title
L P SDLBM6001(a)BM6001(b)BM6001(c)
Bacteriology &immunology Or PharmacologyOr Physiology
55
10
BM6002 Practical Biochemistry Course 60
BM6003 Medical Biochemistry 150 60
BM6004 Molecular Biology 30 30BM6005 Practical and applied Biochemistry
(Cases and problem solving) 30
L: Lecture, P: practical and SDL: Self directed learningb. ElectiveCode Course title No. of hours
L P SDLE6009 Statistics 15
E6018 Bioinformatics 15
6. Program admission requirements: درجة على للحص:::::ول الط:::::الب لقيد ( : يش:::::ترط6) الم:::::ادة
الماجستير:- يك��ون - أن1 إح��دى من والجراحة الطب في البك��الوريوس درجة على حاص��ال
س���نة أمضى قد يك���ون - أن2 معادلة درجة على أو العربية مصر جمهورية جامع���ات الت��دريب ومص�اريف الرس�وم - تس��ديد4 العمل جهة - موافقة3 )االمتي��از( التدريب
- التف��رغ5(�� 1) الملحق في المطلوبة المس���تندات واس��تيفاء األجه���زة واس��تهالك الثاني الجزء امتحان دخول قبل دراسيين فصلين لمدة للدراسة
:- التالية األوراق الماجستير ةلدرج اإللتحاق طالب يقدم( :1) ملحق أو الميالد - شهادة4 اإلمتياز - شهادة3 البكالوريوس - شهادة2 إلتحاق طلب- 1
10
التسجيل على العمل جهة - موافقة6 التجنيد من - الموقف5 رسمي مستخرج يقدم للوافدين - بالنسبة8 جديدة فوتوغرافية صور6 - عدد7 المطلوب والتفرغ صحية شهادة يقدم كما النفقات تحمل جهة ويحدد السفارة موافقة الطالب
7. Regulation for progression and program completion يوليو أول من تبدأ السنة في واحدة مرة للماجستير التسجيل يتم(: 8) مادة
قبول ويجوز عام كل من أكتوبر شهر في الدراسة تبدأ أن على أغسطس أخر حتى ديسمبر أخر نوفمبرحتى أول من الفترة في والوافدين والمعيدين النواب تسجيل
.المطلوبة الدراسة فترة إنقضاء بعد إال األول الجزء إمتحان بدخول لهم يسمح أال على كل مدة دراسيين فصلين على جامعى عام كل فى الدراسة توزع(: 9) مادة
عشر خمسة منهما فبراير. منصف فى الثانى ويبدا أكتوبر أول فى االول . يبدا اسبوعا للفصل التسجيل يتم . و اسابيع ستة لمدة مكثف صيفى دراسى فصل تنظيم مع
المقررات حسب الشروط إستيفاء بعد االقل على بدايته من اسبوعين قبل الدراسى ساعات6 عن الواحد الفصل فى الدراسى العبء يزيد أن المسجلة. والينبغى
الدراسى الفصل بداية من اسبوعين خالل المقررات تعديل للطالب معتمدة. ويجوز المقرارت احد من اسابيع سته خالل االنسحاب له يجوز االضافة(. كما او )بالحذف
احتسابه دون فيه. راسبا هى الماجستير أو الدبلوم درجة على للحصول الدراسة : مدة(: 11) المادة
وعش��رون أربعة الط��الب فيها يجت��از ج��زئين دراس��ية( على فص��ول )أربعة ش��هرا برنامجا تدريبيا ويس��توفى الرابع بالب��اب الموض��حة المعتمدة للساعات طبقا متكامال
قبل اإلمتح��ان ب��دخول له يس��مح وال األنشطة متابعة كتيب فى منة المطلوب خاللها البرنامج من جزء كل في منة المطلوب أرباع ثالثة إستيفاء
:12) المادة فصل األول الج��زء والماجس��تير ال��دبلوم في الدراسة م��دة(: الطالب بعدها يجتاز واحد دراسي لإلنتق��ال بالكامل فيه النج��اح يش��ترط وال إمتحان��ا
لم��دة للت��دريب الط��الب تف��رغ يتطلب الث��اني الث��اني. والج��زء الج��زء في للدراسة.الكلية من المعتمدة المراكز أو المستشفيات بأحد دراسيين فصلين
:: 13) مادة الرس��الة موض��وع بتس��جيل الماجس��تير لدرجة الدارس يقوم(: ويج��وز األقل على واحد دراسي فصل إستيفاء بعد عملي أو نظري بحث شكل على
نجح قد يك��ون أن على األقل على التس��جيل من ش��هور س��تة بعد رسالتة يناقش أن لها صيخص�� وال الثاني الجزء إمتحان دخول وقبل بالكامل األول الجزء مقررات فى
تدرجا::: 14) م::ادة قبل الجامعة متطلب��ات بإس��تيفاء الماجس��تير دارس يق��وم(:
متطلب�اتو .الث��اني الج�زء إمتح�ان دخ��ول قبل الكلية ومتطلب��ات الرس�الة تسجيل درجة450) بمجموع اإلنجليزية اللغة في التويفل شهادة على الحصول هي الجامعة
العليا الدراس��ات لجنة من معتم��دة دورات حض��ور هي الكلية األقل( ومتطلبات على خاصة إختب�ارات بإجتي�از أو الط�بى واإلحصاء العلمى البحث مناهج مجال في بالكليةاللجنة. تحددها
الماجستير درجة إستكمال الدبلوم درجة على للحاصلين يجوز(:: 15) مادة ال��دبلوم درجة على الحص��ول من س��نوات أربع خالل الماجس��تير رس��الة بتس��جيل الرس����الة ومناقشة والكلية الجامعة متطلب����ات إس����تيفاء بعد الدرجة على ويحصلبنجاح.
س�اعة ثالث��ون والماجستير الدبلوم لدراسة المعتمدة الساعات(:: 16) مادة
11
ست وتش��مل األنش��طة متابعة لكتيب ساعات ست منها يخصص األقل على معتمدة الث��اني للج��زء األقل على س��اعة عش��رة وثم��اني األول للج��زء األقل على س��اعاتالماجستير. فى للرسالة ساعات ست إليها ويضاف
سنوات. أربع الماجستير لدرجة القيد مدة(: 22) مادة منها درجة1200 للماجس��تير النهائى االمتحان درجات مجموع(:: 24) مادة
300 ي��وازى بما ال��تراكمى لىص��الف المع��دل اليها األول. ويض��اف للجزء درجة300للماجستير. درجة
ع��ام كل من ونوفم��بر أكت��وبر في األول ال��دور إمتح��ان يعقد(::: 25) م::ادةعام. كل من ومايو أبريل فى الثاني الدور إمتحان ويعقد
بعد والماجس��تير العالى الدبلوم من مادة كل فى النجاح يكون(::: 26) مادة فى النج��اح ويكون مجتمعة المادة لجان لكل الكلية الدرجة % من60 على الحصول
واالكلي��نيكى والعملي التحري��ري درجة % من60 على الحص��ول بعد ال��دكتوراه موادحدة. على كل والشفوي
العليا الدراسات لطالب يمكن القيد مدة إستنفاذ حالة (: فى29) مادة ويجب الرسالة أو األول الجزء فى بالنجاح يعتد وال أخرى مرة التسجيل إعادة
إعادتهما. Assessment Schedule and Weighing of Assessments
Item Mark
Poin
ts
GPA
scor
e
ب
حالةالطال
Stud
ent
stat
e
During semeste
r
End of semeste
rTotal
First semester (If present) 100 300 400Second semester 100 100Third semester 100 100
Fourth semester Final exam
Written
900 900OralPractical /Clinical
Total 300 1200 1500
التالى: الوجه على للنقاط طبقا الطالب درجات تعادل :ملحوظة 4:فأكثر % 90 -1
نقاط
A
أقل% 85من- 2 حتى %90من
:3.67 نقاط
A-
12
أقل% 80من -3 حتى%85من
:3.33 نقاط
B+
أقل% 75من -4 حتى%80من
:3.00 نقاط
B
أقل% 70من -5 حتى%75من
:2.67 نقاط
B-
أقل% 65من -6 حتى%70من
:2.33 نقاط
C+
أقل% 62من- 7 حتى%65من
:2.00 نقاط
C
أقل% 60من -8 حتى%62من
:1.67 نقاط
C-
من -9 Fصفر:%60أقل
والماجستير العالى للدبلوم النهائى االمتحان درجات منها 1200مجموع درجةللدكتوراه 300 النهائى االمتحان درجات ومجموع األول للجزء منها 1500درجة درجة300 . الف المعدل إليها ويضاف وجد إن األول للجزء يوازى صدرجة بما التراكمى 300لى
و والماجستير العالى للدبلوم للدكتوراه 400درجة . درجةالفصلى ( المعدل حساب نقاط) GPAويتم ضرب حاصل مجموع أساس على
المعتمدة الساعات على مقسوما المعتمدة ساعاته عدد فى مضروبا مقرر كل . حساب يتم كما الدراسى الفصل فى الطالب درسها التى المعدل للمقررات
للطالب ( حصل) CGPAالتراكمى التى النقاط ضرب حاصل مجموع أساس علىمجموع على مقسوما المعتمدة ساعاته عدد فى مضروبا مقرر كل فى الطالب عليها
. الكلية المعتمدة الساعاتمن مجموعة أو مادة فى الرسوب حالة الدبلوم مقررات الفى فى
الدكتوراه والماجستير أ . أو فقط المجموعة أو المادة فى اإلعادة حساب يتم ويتمله فيحسب رسوبة تكرر إذا أما فقط إعادة أول فى عليه يحصل الذى الفعلى التقدير
تقدير النجاح اى% (60عند اى 1.67فقط .)C-نقاط
Microbiology and Immunology course specificationUniversity: Ain Shams University Faculty: of Medicine
Course specifications
13
Program on which the course is given: Master degree in Medical Biochemistry and Molecular Biology.Major or minor element of programs: Major Department offering the program: Medical Biochemistry and Molecular Biology.Department offering the course: Microbiology and Immunology Department.Academic Level: Master – 1st semester Date of specification approval: July, 2009…………………………..
A- Basic InformationTitle: Microbiology and Immunology course Code: BM6001(a)Credit Hours: 4 hours Lecture: 55 h Practical: 10 h Total: 65 h
CoordinatorMicrobiology and Immunology Department.
B - Professional Information1- Course Aims:The overall aim of the course:
1. To introduce the candidate to bacterial and viral genetics
2. To enable the candidate to cope with the international standards of Immunology.
Intended Learning Outcomes:
a- Knowledge and understanding:At the end of the course the candidate will be able to:a1- Describe bacterial genetics and antimicrobial drugsa2- Undestand viral structure, classification, and geneticsa3- Understand the natural defense mechanisms.a4- Define the terms, antigens, hapten.a5- Recognize the factors affecting immunogenicity of antigensa6- Understand the phenomenon of self and non-self recognition by the immune system.a7- Describe the two limbs of the immune response (namely, antibody mediated and cell mediated )a8- Understand how active and passive immunity can be acquired and to know the indications for immunization.a 9- Define the term antibody and to know the structure and biological functions of each class of immunogobulins a10- Understand the nature of the Ag-Ab interaction and its in vitro applications in
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the diagnostic microbiological lab.a11- Understand the cellular cooperation and interaction in an immune response and the different mediators involved in immunoregulatory mechanismsa12- Understand the immunological processes underlying protection against microbial disease and tumors.a13- Explain the beneficial role of the immune system in protection against microbial infections and development of tumors.
a14-Discuss means and types of immunization against medically important microorganisms.
a15- Explain the detrimental role of the immune system in hypersensitivity reactions, transplant rejection and development of autoimmune diseases.
a16- Understand the concept of immune deficiency diseases
b- Intellectual Skills: By the end of the course, students should be able to: b1- Integrate basic immunological facts with clinical diseases.b2- Classify oncogenic viruses that place individuals at risk of malignancyb3- Demonstrate abilities to retrieve, analyze, evaluate, and present scientific information by involvement in problem solving activities.
c- Professional and Practical Skills: By the end of the course, students should be able to: c1- Use informational technologies and library resources in the field of immunology and microbiology.c2- Communicate information with teaching staff and colleguesc3- Use the internet to retrieve and to present information.c4- Apply safety measures in the laboratory to prevent contamination of the lab and equipments. d- General and Transferable Skills: By the end of the course, students should be able to: d1- Adopt the principles of life-long learningd2- Retrieve, manage, and manipulate information by all means, including electronic means.d3- Present information orally, electronically, or by written meansd4- Effectively manage time and resources and set prioritiesd5- Work in a team in the lab. and cooperate with colleagues and staff.d6- Utilize problem solving skills in a variety of theoretical and practical situations.
15
Contents of the course:
No. of hours
L T C/P
SDL
General bacteriology:
10 6
Virology:1- Viral structure2- Classification of viruses3- Viral replication4- Viral genetics.
10
Immunology:
I. THE INNATE IMMUNE SYSTEM
A. The Innate Immune System: An Overview
B. Pathogen-Associated Molecular Patterns (PAMPs), Pattern-Recognition Receptors (PRRs), and Cytokines
C. Cells Involved in Body Defense
D. Anatomical Barriers, Mechanical Removal, Intraepithelial T-Lymphocytes and B-1 Cells, Bacterial Antagonism by Normal Flora, and Antigen-Nonspecific Antimicrobial Chemicals Produced by the body
E. The Complement System :
F. Phagocytosis
G. Natural Killer (NK) Cells
H. Inflammation
35 4
16
I. Nutritional Immunity
J. Fever
K. The Acute Phase Response
II. ADAPTIVE IMMUNITY
A. Overview of Adaptive Immunity
B. Major Cells and Key Cell Surface Molecules Involved in the Immune Responses
C. The Lymphoid System
D. An Overview of the Steps Involved in Adaptive Immune Responses
IIa. HUMORAL IMMUNITY
A. Antibodies (Immunoglobulins)
B. Ways That Antibodies Help to Defend the Body
C. Naturally and Artificially Acquired Active and Passive Immunity
D. Monoclonal Antibodies
IIb. CELL-MEDIATED IMMUNITY
A. The Steps Involved in Cell-Mediated Immunity
B. Ways That Cell-Mediated Immunity Help to Defend the Body
D. Active and Passive Immunotherapy to Stimulate Cell-Mediated Immunity against Tumors
III. IMMUNODEFICIENCYA. Primary ImmunodeficiencyB. Secondary Immunodeficiency
IV. HYPERSENSITIVITIES
A. Immediate Hypersensitivities
17
B. Delayed Hypersensitivities (Type IV)
C. Superantigens
Learning methods:1. Lectures and small group discussion2. Seminars3. Practical classes4. Self directed learning
Methods of assessment:1. Written exam to assess knowledge, understanding and intellectual skills1. Oral exam to assess the ability to identify and apply immunological
knowledge in a comprehensive oral way.2. Practical exam assess practical and intellectual skills
Weighing of Assessments:
End-semester MCQ &Written Exam 150 marks End-semester Oral Examination……………. 30 marks End-semester Practical Examination 20 marks
Total ……………. 200 marks
List of references Course notes: Medial microbiology and Immunology Department books Essential books:
Lecture Notes: Immunology (Todd and Spickett) Recommended Books
Medical Immunology (Parslow, Stites, Terr & Imoboden)Immunobiology (Janeway, Travers, Walport, Shlomchik)Medical Microbiology & immunology (Levinson & Jawetz)
Pharmacology course specificationUniversity: Ain Shams University Faculty: of Medicine
Course specificationsProgram on which the course is given: Master degree in Medical Biochemistry and Molecular Biology.Major or minor element of programs: Major
18
Department offering the program: Medical Biochemistry and Molecular Biology Department.Department offering the course: Pharmacology Department. Academic Level: Master – 1st semester Date of specification approval: …………………………..
A- Basic InformationTitle: pharmacology course Code: BM6001(b)Credit Hours: 4 hour Lecture: 55 Practical: 10 Total: 65CoordinatorPharmacology Department.
B - Professional Information1- Course Aims:
The aim of this course is to provide students with an understanding of the principles of pharmacology related to dosing, pharmacokinetics, biotransformation, mechanisms of action, side effects, drug interactions, and compliance issues,
2- Intended Learning Outcomes (ILOs) from the Course:a- Knowledge and understanding By the end of the course the candidate will be able to:
a1) Discuss the pharmacokinetic, pharmacodynamic and pharmaco-therapeutic properties of drugs.
a2) Discuss the adverse and toxic effects of drugs, and their management. a3)Give an account on limitations to the use of drugs such as
contraindications and drug interactions.a4) Define clinically relevant age, sex and genetic related variations that
affect response to drugs.a5) Define the principles, the indications, the relative advantages and
disadvantages of various pharmacotherapy modalities.A6) Recognize the rational and general guidelines of the use of drugs in the
proper dose in special population such as pediatrics, geriatrics, pregnancy and lactation and in cases of liver and kidney impairment.
b- Intellectual skillsBy the end of the course the candidate will be able to: b1) Calculate accurately drug’s dosage, bioavailability, plasma half life and volume of distribution in different patient populations.b2) Document drug adverse reactions.b3) Observe, record and analyze the effect of drugs on biological tissues
19
c- Professional skillsBy the end of the course the candidate will be able to:
c1) Think independently, evaluate and reflect, set tasks and select appropriate and reasoned approaches to solve problems; c2) Use knowledge and understanding of the pharmacological sciences to formulate and apply the principles of scientific inquiry to address pharmacology-related problems; c3) Apply the knowledge and understanding of the pharmacological sciences to plan and undertake hypothesis-driven pharmacological research.c4) Demonstrate confidence and competency in understanding, analysing and interpreting pharmacological data d- General and transferable skills By the end of the course the candidate will be able to:
d1 - Understand the importance of life-long self-learning and show a strong commitment to it.d2 - Use current I.T. for appropriate drug database to reach information about a specific medication. d3- Respect ethics related to drug prescription and use especially to drugs liable to produce abuse. 3- Course content:
Topics No of hoursL C/P SDL
20
(1) General pharmacology:Evaluation of new drugsPharmacokinetics BiotransformationPharmacodynamicsAdverse Drug InteractionPharmacogenetic disordersDrug AllergyDrug interactions
10 5
(2) Pharmacology of Blood
Drug therapy of thrombosis
Anticoagulants
Antiplatelet drugs ( Anti-Thrombotics )
Fibrinolytics ( Thrombolytics )
Drugs used in bleeding disorders
Vitamen K
Fibrinolytic Inhibitors ( Antiplasmin )
Drug therapy of Anemia
Drug-induced blood disorders
Drug therapy of hyperlipidemia
Management of Hyperlipidemias
10 5
(3)- Renal Pharmacology
Diuretics
Drugs and Potassium Homeostasis
Disturbances in K+ serum level
10
21
Drugs and Acid-Base Balance
Treatment of renal stones
(4)-Endocrine Pharmacology
Insulin & oral antidiabetic drugs
Drugs Affecting Bone calcium Homeostasis
Hypothalamic & pituitary hormones
Thyroid hormones and antithyroid drugs
Anti thyroid drugs
Corticosteroids
Sex hormones
15
(5)- Chemotherapy
Antibacterial Chemotherapy
Cytotoxic drugs
10
L: Lectures and SDL: Self directed learning
4 - Student Assessment Methods4.1 written exam to assess knowledge, skills4.2 Oral exam to assess General and transferable skills 4.3 Practical exam to assess practical and intellectual skills
Weighing of assessment
End-semester MCQ &Written Exam 150 marks End-semester Oral Examination……………. 30 marks End-semester Practical Examination 20 marks
Total ……………. 200 marks
5 -- List of References5.1- Course Notes (paper and / or electronic): Deparment Book5.2- Essential Books (Text Books)5.3- Recommended BooksPrinciples of Clinical Pharmacology
22
5.4- Periodicals, Web Sites, etchttp://www.centerwatch.com/drug-information/fda-approvals/drug-areas.aspx?AreaID=8http://www.medilexicon.com/drugsearch.php?a=19http://www.chilanti.com/olbooks/medbooks/Cochrane_Musculoskeletal_Group.htm
Medical Physiology Course Specification:University: Ain Shams University Faculty: of Medicine
Course specificationsProgram on which the course is given: Master degree in Medical Biochemistry and Molecular Biology.Major or minor element of programs: Major Department offering the program: Medical Biochemistry and Molecular Biology Department.Department offering the course: Medical Physiology Department. Academic Level: Master – 1st semester Date of specification approval: July, 2009………………………..
A- Basic InformationTitle: Medical Physiology course Code: BM6001(c)Credit Hours: 4 hour Lecture: 55 h Practical: 10 h Total: 65 h
CoordinatorMedical Physiology Department.
B - Professional Information1- Course Aims:
a- To understand functions of different body systems and organs.b- To integrate regulatory mechanisms of different body functions in
health & disease states
2- Intended Learning Outcomes (ILOs) from the Course:a- Knowledge and understandingBy the end of the course the candidate will be able to:
a1-Recognize the functions of different body systems and the mechanisms involved in its regulation a2-Describe how different body functions are integrated to maintain homeostasis
23
a3-Interprete & explain disturbed body functions in different diseases
b- Intellectual skillsBy the end of the course the candidate will be able to: b1- Analyze the given information. b2- Think and expect the outcome of disturbed function b3- Solve problems through case study and choose the best from multiple . b4- Hypothesize and experiment physiological principles
c- Professional skillsBy the end of the course the candidate will be able to:c1- Carry out all experiments in practical physiology classes
Blood tests .e.g. Blood groups , E.S.R.. Haemostatic function (bleeding time,clotting time),hemoglobin, hematocrite value and capillary fragility.
metabolic rate – oxygen consumpt perform isolated perfused organ study, nerve & muscle preparation.
C4-Use different equipments in physiology department for scientific rsearch.
d- General and transferable skills By the end of the course the candidate will be able to:
d1- communicate with medical students in practical classes and small group discussions.
d2-communicate with staff members in physiology department and other departments.
d3- present seminars in different issues in physiology in scientific meetings & medical conferences.
3- Course contentsTopics No. of hours
(I) General & cellular Basis of Medical Physiology:1. Homeostasis and feedback mechanisms.
L P SDL
24
2. Cell membrane (structure, characteristics & channels).
3. Transport across cell membrane.4. Membrane potentials (resting membrane
potential and action potentials).5. Second messenger pathways.6. Cellular organelles and their functions.7. Cybernetics in physiology.8. Receptors in physiology.9. Body fluids and water balance.
10٭
(II) Physiology of Nerve and Muscle:1. Types of muscles (skeletal, cardiac & smooth
muscles).2. Electrical activity of nerve & muscle (resting
membrane potential and action potential).3. Neuromuscular junctions and excitation
contraction coupling.4. Conduction of nerve impulse.5. Energy sources & metabolism of skeletal
muscle.6. Physiology of smooth muscles.7. Assessment of muscle and nerve functions.8. Effects of nerve lesions (degeneration &
regeneration).
10 ٭
(III) Physiology Of Blood:1. Physiology of red blood cells.2. Normal and abnormal haemoglobins.3. Haematopoiesis, anaemias and polycythemia.4. Blood groups and blood transfusion.5. Physiology of leucocytes.6. Immune mechanisms, allergy , anaphylaxis &
autoimmune disorders.7. Platelet physiology .8. Haemostasis, coagulation, fibrinolysis and
anticlotting mechanisms. Common coagulation disorders.
9. Hormones affecting the different components of
10
25
blood.10. Plama proteins: types, origins, concentrations and functions- hypoproteinemia.11. Functions of spleen and reticulo-endothelial system.12. Physiology of tissue macrophage system.13. Physiology of lymph.
(IV) Energy & General Metabolism:1. Thermoregulation and fever hypo-&
hyperthermia.2. Energy balance, control of food intake,
obesity, under & malnutrition, leptin.3. Metabolic rate and BMR4. Respiratory Quotient(R.Q)
5
(V) Endocrine Physiology:1. General concepts in endocrine physiology.2. Mechanism of action of hormones.3. Control of endocrine functions (role of
hypothalamus,hypothalamic–pituitary relationship).
4. Physiology of pituitary gland and its disorders.5. Physiology of thyroid gland its disorders.6. Physiology of adrenal cortex and its disorders.7. Calcium homeostasis and Tetany.8. Glucose homeostasis and pancreas & diabetes
mellitus.9. Physiology of growth–Insulin like growth
factors.10. Physiology of puberty.11. Magnesium homeostasis.12. Phosphorus homeostasis and physiology of bone.13. Ectopic hormones.
14. Prostaglandins and their physiologyical significance.
10
26
VI) Physiology of Kidney and Body Fluids:1. Functional structure.2. Kidney functions in the regulation of body
fluids. Role of ADH in the regulation of total body water.
3. Renal circulation and renal blood flow.4. Glomerular filteration and autoregulation.5. Tubular function reabsorption and secretion.6. Plasma clearance, renal handling of Na,
glucose. Bicarbonate & NH3.7. Regulation of excretion Na, CI & K.8. Acid–base balance and its disturbances.
Anion gap.9. Concentration, dilution & acidification of
urine.Micturition and its disorders.
10
Practical Course For M.Sc. Physiology (1) Smooth Muscle and Autonomic Receptors:
(2) Blood Physiology: Determination of hemoglobin content. Determination of packed cell volume
(Haematocrit value)- Anemia – Polycythemia – Blood indices.
Erythrocyte sedimentation rate (ESR). Osmotic fragility test. Evaluation of hemostatic function of blood:
a. Determination of the bleeding time.b. Determination of whole blood clotting time.c. Determination of prothrombin time (PT).d.Determination of activated partial thromboplastin time (APTT). - (Purpura–Haemophilia–Hypoprothrombinemia-Hypofibrinogenemia – Hypercoagulability states).
Blood groups:a. ABO.
10
L: Lecture, T: Tutorial, C/P: Clinical or Practical and SDL: Self directed learning
27
4 – Teaching and Learning Methods 4.1-Practical lessons
4.2-Discussion sessions4.3-Research assignment4.4-Self directed learning4.5-E-learning
5- Student Assessment Methods5.1 Written Exam. to assess:Knowledge & understanding and intellectual skills5.2 Practical Exam to assess: Professional& practical skills 5.3 Oral Exam to assess|:General & transferable skillsWeighing of assessment:
End-semester MCQ &Written Exam 150 marks End-semester Oral Examination……………. 30 marks End-semester Practical Examination 20 marks
Total ……………. 200 marks 6 -- List of References
6.1- Course Notes: Lecturer notes6.2- Essential Books (Text Books)
o Review of medical physiology By: William F. Ganong o Text Book of medical physiology By: Guyton.o BEST AND TAYLOR ’ s Physiological basis of Medical practice.
6.3- Recommended Books:o Human physiology from cell to system By: Lauralee Sherwood.
6.4- Periodicals, Web Sites, … etco www. Pubmed.com.o Ain Shams medical journalo Am. J. of physiology.o http:// mic2.shams.eg ( Faculty web site)
Course specifications of Practical BiochemistryUniversity Ain Shams Faculty of MedicineProgramme(s) on which the course is given: Master of Science in Medical
Biochemistry and Molecular Biology
Major or minor element of programmes: Major
Department offering the programme: Medical Biochemistry & Molec. Biology
Department offering the course: Medical Biochemistry and Molecular Biology
28
Academic Level: MSc., first semester
Date of specification approval: July, 2009
A- Basic InformationTitle: Master of Science in Medical Biochemistry and Molecular Biology Code: BM6002Credit Hours: 2 credit hours Lecture: Tutorial: Practical: 60 h Total: 60 hCo-ordinator: Department of Medical Biochemistry and Molecular Biology
B - Professional Information1- Course Aims:
1- To provide the students with a solid background of practical biochemistry concepts and skills and relate them to the theoretical biochemical information.
2- To equip the students with preliminary knowledge and skills necessary for Biochemistry research 2- Intended Learning Outcomes (ILOs) from the Course:
a- Knowledge and understanding By the end of the course the candidate should be able to:
a1) Describe how to express the concentration of solution using SI units, and how to change the concentration by dilution.
a2) Understand the steps of preparation of acids and bases.a3) Describe the mechanism of buffering and important physiological
buffers. a4) State the laws of spectrophotometry, compare qualitative to
quantitative assays, and compare direct to coupled enzyme assays.
b- Intellectual skillsBy the end of the course the candidate will be able to:
b1- Integrate laboratory biochemical results with clinical data.b2- Analyse and interpret the results of biochemical experiments.
c- Professional and Practical skills By the end of the course the candidate should be able to:c1-Demonstrate a professional attitude and good communication skills by effective participation in cooperative problem solving, in small group exercises directed towards understanding the biochemical and genetic bases of disease origins, diagnoses and treatments
29
c2- Apply different methods for expression of concentration and calculation of the dilution of solution.c3- Demonstrate ability to prepare buffers and chose the proper buffer for each medium.c4- Use spectrophotometric assay methods to determine the concentration of proteins and enzymes. c5- Follow proper method of disposal of biohazardous samples (infectious, carcinogenic, etc.).c6- Use the computer to retrieve and compare practical biochemistry data
d- General and transferable skills By the end of the course the candidate will be able to:
d1 – Develop the skill of working in teams d2 – Develop appropriate relationships with patient and family d3- Use basic computing skills and internet to follow electronic lectures d4- Communicate relevant information with teaching staff and colleagues
3- Course content:
PRACTICAL BIOCHEMISTRY L C/P SDLLab orientation and lab safety 2Sampling procedures and tubes 4Expression of concentration of solutionsConversion to SI units
4
Changing concentration by dilution 4
Preparation of acids and bases 4
Diffusion through membranes:-Dialysis-Osmosis-Osmotic behaviour of living cells
4
Water dissociation and pHAcids and basesStrong and weak acidsKa and pKa of weak acids
6
Preparation of buffers 6
30
Spectrophotometry: -Lambert’s law -Beer’s law -Qualitative spectrophotometric assays. - Quantitative spectrophotometric assays. - Construction and properties of a spectro-photometer. - Direct and coupled enzyme assay
10
Measurement of total serum proteins 4
Measurement of Blood glucose:OGTTGlycosylated Hb and fructosamine
6
Assessment of serum lipid profile 6
L: Lecture, T: Tutorial, C/P: Clinical or Practical and SDL: Self directed learning
4 - Student Assessment Methods 5.1- Class Discussions: to detect weak points and to emphasize important points5.2- Practical exam: to assess professional and practical skills.
Weighing of Assessments: (1) End first semester practical exam 100 marks Total ……………. 100 marks
Any formative only assessments: Non
End semester exams:1st semester: 100 marks
5 -- List of References
5.1- Course Notes (paper and / or electronic)Practical Biochemistry Department book provided by the staff of Medical Biochemistry and Molecular Biology…………………………………………5.2- Essential Books (Text Books)
Experimental Biochemistry Theory and Exercises in Fundamental Methods, Robert Switzer and Liam Garity, 3rd edition
31
Analytical Biochemistry, David J Holme and Hazel Peck, 1998, Pearson educ., Addison Wesley Longman limited.
Medical Biochemistry course specificationUniversity: Ain Shams University Faculty: of Medicine
Course specificationsProgram on which the course is given: Master degree in Medical biochemistry and Molecular Biology Major or minor element of programs: Major Department offering the program: Medical Biochemistry and Molecular Biology DepartmentDepartment offering the course: Medical biochemistry and Molecular Biology DepartmentAcademic Level: Master – Second semester Date of specification approval: July, 2009
A- Basic InformationTitle: Medical biochemistry course. Code: BM6003Credit Hours: 12 hour Lecture: 160 h Practical: 40 Total: 200
Coordinator: Medical Biochemistry and Molecular Biology Department
a- Professional Information
1 – Overall Aims of Course
To provide postgraduate students with a basic understanding of the biological processes in humans at a molecular level and to correlate any molecular defect or abnormality to medical problems
To provide postgraduate students with an integrated knowledge of how energy is stored, retrieved and generated (metabolism) as well as the daily energy expenditure and the acceptable dietary macronutrient and micronutrient intake values with reference to malnutrition, overweight and obesity.
32
To provide the environment necessary to develop skills in self-evaluation, self-directed learning and critical appraisal enabling the medical biochemist to adapt to the rapid progress of information and changes that will occur in the profession throughout their careers. 2 – Intended Learning Outcomes of Course (ILOs)
b-Knowledge and Understanding: By the end of the course, students should be able to:
a1-Discuss normal biochemical pathways and the etiology and pathogenesis of the biochemical disorders of disease
a2- Describe the structure function relationship of some important proteins: hemoglobin, myoglobin, skeletal muscles, collagen, and immunoglobulins.a3- Explain the methods of classification and regulation of enzymes as well as kinetics of enzymes and coenzymes. a4- Describe the structure of biological membranes and classify the different mechanisms of signal transduction across membranesa5- Describe the metabolic pathways of carbohydrates, lipids, and proteins, their energetics, their sites, and the ways of their regulation.a6- Define the possible metabolic errors arising from deficiency of certain metabolic enzyme a7- Describe the components of mitochondrial ETC and their inhibitors. a8- Point out sources and fate of ammonia in human body and the causes of ammonia intoxication. a9- Define which nitrogenous compounds are derived from each amino acid and describe their synthesis, degradation and functions.a10- Explain the different patterns of fuel metabolism in different organs, during the fast and fed statesa11- Describe the composition of blood and explain the mechanism of blood clotting, anticoagulation and fibrinolysis. a12- Summarize the functions and deficiency diseases of vitamins and minerals.a13-Summarize the various mechanisms of xenobiotic metabolisma14- Identify cell adhesion molecules b-Intellectual Skills: By the end of the course, students should be able to: b1- Integrate basic biochemical facts with clinical diseases.b2- Identify electrophoretic bands, interpret disease-associated changes in plasma proteins and diagnose sickle cell trait and sickle cell anemia b3- Solve any subject-related problems provided by staffb4- analyze laboratory data using statistical rules.
33
c- Professional and Practical Skills: By the end of the course, students should be able to: c1- Demonstrate ability to choose the type of protein assay in a given biologic fluid.c2- Separate proteins by molecular sieving, and by ion exchange or thin layer chromatography c3- Perform different types of assays as ELISA, immunodiffusion.c4- Identify and interpret electrophoresis results of different types.c5- Apply methods to prevent contamination of the lab and equipments.c6- Follow proper method of disposal of biohazardous samples (infectious, carcinogenic, etc.).c7- Perform urine and stone analysis.
d- General and Transferable Skills: By the end of the course, students should be able to: d1- Work in a team in the lab and cooperate with their colleagues and staff.d2- Use basic computing skills and internet to fulfill problem-based learning d3- Communicate relevant information with teaching staff and colleagues
3- Contents Topic L C/P SDL
Water, acids, bases and buffers 2Chemistry of amino acids and proteins 4
Protein structure-function relationship: -Hemoglobin and Myoglobin -Immunoglobulins -Collagen and elastin -Plasma Proteins -Muscle proteins
10
Enzymes 8
Carbohydrate chemistry and metabolism 20Bioenergetics and Biological oxidation 5Lipid chemistry and metabolism 20O2 toxicity and free radical injury 2Metabolism of ethanol 2Protein Metabolism:General protein metabolismIndividual amino acid metabolism
20
34
Integration of Metabolism 4Diabetes mellitus 3Biological membranes 2Biosignalling 10Apoptosis 2Metabolism of Nucleotides 4Iron and Heme Metabolism 5Nutrition-malnutrition and obesity 5Vitamins and Mineral Metabolism 8Metabolism of Xenobiotics 5Blood composition, Blood coagulation and fibrinolysis
4
PRACTICAL BIOCHEMISTRY
Urine analysis 5
Stone analysis 5
Protein purification:- Molecular sieving- Ion exchange chromatography- Affinity chromatography- Thin layer chromatography- How to check protein purity
10
Assay of proteins in biologic fluids: -Simple colorimetric assay -Turbidimetric assay -ELISA -RIA -Immunohistochemistry -Immunodiffusion
10
Electrophoresis: - General principals - Cellulose acetate membrane electophoresis - Polyacrylamide gel electroph. - DNA and RNA electrophoresis using agarose gel - Gel photography
10
35
4– Teaching and Learning Methods
4.1- Lectures: using data show and overhead projectors 4.2- Practical Training 4.3- Discussion sessions: as journal clubs and seminars 4.4- Collection of information using the internet
5- Student Assessment Methods
5.1- Class Discussions: to detect weak points and to emphasize important points5.2- Quizes at the end of each subject to assess understanding and weak points5.3- Oral exam: to assess knowledge, understanding and information presentation ability5.4- Practical exam: to assess practical skills aquired by students5.5- Written end-year exam to assess knowledge and understanding.
Weighing of Assessments: (1) Periodic quizzes 70 marks(2) Written exam 200 marks (4) Practical exam (Cases and Skills) 240 marks (5) Oral exam 090 marks
Total ……………. 600 marksAny formative only assessments: Non
End semester exams: 2nd semester: 85 marks 3rd semester: 65 marks
6 -- List of References6.1- Course Notes (paper and / or electronic)
Lectures notes and Practical Biochemistry book provided by the staff of Medical Biochemistry and Molecular Biology Department.
6.2- Essential Books (Text Books)
36
Lippincott's Illustrated Reviews: Biochemistry, Champe PC, 4 th edition. Lippincott Williams & Wilkins Pub., 2009.
Harper's Illustrated Biochemistry, Robert K. Murray RK, Granner DK, Mayes PA and Rodwell VW 27th edition, McGraw-Hill Medical Pub., 2006.
Lehninger Principles of Biochemistry, Nelson DL and Cox MM, 5th edition, Freeman Pub, 2009.
Biochemistry lecture notebook, Berg JM, Tymoczko JL and Stryer L, 6th edition, Freeman Pub., 2006.
6.3- Recommended BooksBiochemistry: A Case Oriented Approach, Montgomery R et al, 6th edition, Mosby, 1996. USMLE Road Map Biochemistry, Macdonald R, 1st edition. McGraw-Hill Medical Pub., 2007.
Textbook of Biochemistry with Clinical Correlations, Devlin TM, 6th edition, Wiley-Liss, Inc. Pub., 2005.
6.4- Periodicals, Web Sites, … etc
http://mic2.shams.edu.eg/moodle www.medicaleducationonline.org www.eul.edu.eg www.wilkpedia.com www.encyclopedia.com Molecular Biology Course specifications:University Ain Shams Faculty of MedicineProgramme(s) on which the course is given: Master of Science in Medical
Biochemistry and Molecular Biology
Major or minor element of programmes: Major
Department offering the programme: Medical Biochemistry and Molecular
Biology
Department offering the course: Medical Biochemistry and Molecular Biology
37
Academic Level: MSc. 1st part
Date of specification approval: July, 2009
A- Basic InformationTitle: Master of Science in Medical Biochemistry and Molecular Biology Code: BM6004Credit Hours: 3 credit hours Lecture: 38 h Tutorial: Practical: 14 h Total: 52 h
Co-ordinator: Department of Medical Biochemistry and Molecular BiologyB - Professional Information
1- Course Aims: 1- To provide students with advanced information concerning the human genome, human genetics and the future of diagnostic and therapeutic medicine.
2- To equip the students with the specialized knowledge and skills necessary for future research in molecular biology. 2- Intended Learning Outcomes (ILOs) from the Course:
a- Knowledge and understanding
By the end of the course the candidate will be able to:
a1) Understand the structure, function and organization of human genomes a2) Describe the main principles of methods for preparation and extraction of DNA and RNA.a3) Understand the main principles of methods for DNA amplification (PCR, RT-PCR, Real-time PCR, etc.)a4) Identify the main principles of methods for DNA sequencinga5) Describe the main principles of DNA and RNA blottinga6) Understand the concepts of recombinant DNA technology a7) Understand the applications of molecular biology techniques in the diagnosis, taxonomy, species and strain differention of microorganisms. .a8) Understand the applications of molecular biology techniques in genetic testing, in paternity testing, studying drug resistance, and vaccine and drug development. a9) Point out the principle of microarrays
b- Intellectual skills
38
By the end of the course the candidate will be able to:
b1- Integrate basic molecular biology facts with clinical data.b2- Identify the appropriate experimental technique required to diagnose a genetic disease. b3- Analyse and interpret the results of molecular biology techniques.
c- Professional and Practical skills By the end of the course the candidate will be able to: c1- Incorporate new molecular biology knowledge and tools into research
projects c2- Use the computer to retrieve and compare molecular biology data c3- Solve any subject-related problems provided by staff c4- Apply methods to prevent contamination of the lab and equipments.
c5- Follow proper method of disposal of biohazardous samples (infectious, carcinogenic, etc.). c6- Demonstrate the ability to extract DNA and RNA c7- Interpret the results of PCR and RT-PCR, blotting teckniques, and DNA
finger printing
d- General and transferable skills By the end of the course the candidate will be able to:
d1 – develop the skill of working in teams d2 – develop appropriate relationships with patient and family d3- Use basic computing skills and internet to follow electronic lectures d4- Communicate relevant information with teaching staff and colleagues d5) Search gene and protein Database. d6) Use molecular biology software.
3- Course content:
Basic principles in molecular biology L (1h) P SDL1- Nucleic acid structure and organization 42- Cell cycle, DNA replication and repair 43- RNA transcription and processing 44- Regulation of gene expression 45-The Genetic code, mutation and protein synthesis
4
6- Cloning: 4
39
Gene (DNA) cloningReproductive cloningTherapeutic cloning7- Techniques of genetic analysis -Extraction of DNA & RNA - PCR & RT-PCR - DNA electrophoresis - Blotting techniques - RFLP - Microarray
10
8- Genetic variation & DNA finger printing
4
9- Molecular biology of cancer - Oncogenes, - Tumor suppressor genes, - Apoptosis - Telomerase - invasion and metastasis - Angiogenesis
4
10- Transgenesis & Gene Therapy
6
11- Stem cells 4
13-Ethical, Legal, and Social implications of genetic knowledge
4
14- Personalized Medicine 2
L: Lecture, T: Tutorial, C/P: Clinical or Practical and SDL: Self directed learning
4 - Student Assessment Methods 5.1- Class Discussions: to detect weak points and to emphasize important points5.2- Quizes at the end of each subject to assess understanding and weak points5.3- Written final exam to assess knowledge and understanding.Weighing of Assessments:
(1) Written end-sec part exam 150 marks
40
Total ……………. 150 marks
Any formative only assessments: Quizes at the end of each
End semester exams:2nd semester: 15 marks
3rd semester : 15 marks
6 -- List of References6.1- Course Notes (paper and / or electronic)
Lectures notes and Practical Biochemistry book provided by the staff of Medical Biochemistry and Molecular Biology Department.
6.2- Essential Books (Text Books)
Biochemistry: A Case Oriented Approach, Montgomery R et al, 6th edition, Mosby, 1996. USMLE Road Map Biochemistry, Macdonald R, 1st edition. McGraw-Hill Medical Pub., 2007.
Textbook of Biochemistry with Clinical Correlations, Devlin TM, 6th edition, Wiley-Liss, Inc. Pub., 2005.
6.3- Recommended BooksLippincott's Illustrated Reviews: Biochemistry, Champe PC, 4 th edition. Lippincott Williams & Wilkins Pub., 2009.
Harper's Illustrated Biochemistry, Robert K. Murray RK, Granner DK, Mayes PA and Rodwell VW 27th edition, McGraw-Hill Medical Pub., 2006.
Lehninger Principles of Biochemistry, Nelson DL and Cox MM, 5th edition, Freeman Pub, 2009.
Biochemistry lecture notebook, Berg JM, Tymoczko JL and Stryer L, 6th edition, Freeman Pub., 2006.
5.4- Periodicals, Web Sites, etchttp://www.web-books.com/MoBio/http://www.coe.uncc.edu/~hhilger/EB_I_F_06/web_links_on_basics_of_molecular_biology.htm
41
http://plato.acadiau.ca/courses/biol/Microbiology/Basics.htmhttp://www.wiley.com/legacy/college/boyer/0470003790/animations/cell_structure/cell_structure.htmhttp://www.cellsalive.com/cells/3dcell.htmhttp://www.johnkyrk.com/DNAanatomy.html http://www.johnkyrk.com/DNAreplication.htmlhttp://www.johnkyrk.com/DNAtranscription.html http://www.johnkyrk.com/DNAtranslation.html http://www.rothamsted.ac.uk/notebook/courses/guide/http://www.bio.com/protocolstools/protocol.jhtml?id=p1242 http://users.ugent.be/~avierstr/principles/pcr.html http://depts.washington.edu/genetics/courses/genet371b-aut99/PCR_contents.html [animation]http://www.sumanasinc.com/webcontent/anisamples/molecularbiology/pcr.html [animation] http://www.sumanasinc.com/webcontent/anisamples/molecularbiology/molecularbiology.html (animated techniques
Course specifications of Applied BiochemistryUniversity Ain Shams Faculty of MedicineProgram(s) on which the course is given: Master of Science in Medical
Biochemistry and Molecular Biology
Major or minor element of programmes: Major
Department offering the programme: Medical Biochemistry and Molecular
Biology
Department offering the course: Medical Biochemistry and Molecular Biology
Academic year: MSc. Second Part
Date of specification approval: July, 2009
A- Basic InformationTitle: Master of Science in Medical Biochemistry and Molecular Biology Code: BM6005Credit Hours: 2 credit hours Lecture: 30 h Tutorial: Practical: h Total: 30 h
Co-ordinator: Department of Medical Biochemistry and Molecular Biology
B - Professional Information
42
1- Course Aims:
To provide the postgraduate students with the opportunity to apply biochemical knowledge and molecular biology information in problem solving and case interpretation
Equipping of the students with the specialized knowledge and skills necessary to be a professional of medical biochemistry laboratory. 2- Intended Learning Outcomes (ILOs) from the Course:
a- Knowledge and understanding By the end of the course the candidate should be able to:
a1) Point out the various metabolic and genetic diseases related to each course topic.
a2) Understand how to use biochemical and molecular biology knowledge in the diagnosis and interpretation of clinical picture of patients.
b- Intellectual skillsBy the end of the course the candidate will be able to:
b1- Integrate basic biochemical and molecular biology information with clinical diseaseb2- Analyse and interpret laboratory and clinical data to reach a diagnosis and predict the course of a disease.
c- Professional and Practical skills By the end of the course the candidate should be able to:c1-Demonstrate a professional attitude and good communication skills by effective participation in cooperative problem solving, in small group exercises directed towards understanding the biochemical and genetic bases of disease origins, diagnoses and treatmentsc2- Apply different methods for expression of concentration and calculation of the dilution of solution.c3- Demonstrate ability to prepare buffers and chose the proper buffer for each medium.c4- Demonstrate ability to interpret different molecular biology techniques in the diagnosis of hereditary diseasesc5- Identify and interpret electrophoresis results of different types.c-6 Interpret the results of PCR and RT-PCR and DNA finger printing d- General and transferable skills
43
By the end of the course the candidate will be able to: d1 – Develop the skill of working in teams d2 – Develop appropriate relationships with his colleagues and staff members. d3- Use basic computing skills and internet to follow electronic lectures d4- Communicate relevant information with teaching staff and colleagues Course contents:
L PProblems related to:Preparation of solutions Changing concentration by dilutionPreparation of acids, bases, and buffersOsmosis, dialysis, ..
2
Cases and problems related to:Protein folding and misfoldinge.g. Alzheimer De.g. Prion disease
1
Cases and problems related to: -Hemoglobinopathies -Collagin and elastin
2
Cases and Problems related to:Enzyme kineticsEnzyme inhibitorsEnzymes in clinical diagnosis
2
Cases and problems related to:Carbohydrate metabolism
2
Cases and problems related to:Bioenergetics and Biological oxidation
2
Cases and problems related to:Lipid metabolism metabolism
2
Cases and problems related to:Protein Metabolism
2
Cases and problems related to: Integration of Metabolism Starvation Metabolism of special organs
2
Cases and problems related to:Diabetes mellitus
2
Cases and problems related to:Biological membranes
1
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Biosignalling Cases and problems related to:Defective nucleotide metabolism:e.g. Gout
2
Cases and problems related to: HyperbilirubinemiaPorphyria
2
Cases and problems related to:NutritionObesityVitamin deficiency
2
Cases and problems related to:Defective mineral metabolism: e.g. Hypocalcemia and hypercalcemia e.g.Wilson D e.g. Congenital and aquired iron overload
2
Cases and problems related to:DNA damage and repairPosttranscriptional modificationGenetic code and mutationsTechniques of genetic testingDNA finger printing
2
4 - Student Assessment Methods 5.1- Class Discussions: to detect weak points and to emphasize important points5.2- Written exam: to assess knowledge and understanding.
Weighing of Assessments: (1) End sec part written exam 100 marks Total ……………. 100 marks
Any formative only assessments: periodic
End semester exams:3rd semester: 20 marks
6 -- List of References6.1- Course Notes (paper and / or electronic)
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Lectures notes and Practical Biochemistry book provided by the staff of Medical Biochemistry and Molecular Biology Department.
6.2- Essential Books (Text Books)
Biochemistry: A Case Oriented Approach, Montgomery R et al, 6th edition, Mosby, 1996. USMLE Road Map Biochemistry, Macdonald R, 1st edition. McGraw-Hill Medical Pub., 2007.
Textbook of Biochemistry with Clinical Correlations, Devlin TM, 6th edition, Wiley-Liss, Inc. Pub., 2005.
6.3- Recommended BooksLippincott's Illustrated Reviews: Biochemistry, Champe PC, 4 th edition. Lippincott Williams & Wilkins Pub., 2009.Harper's Illustrated Biochemistry, Robert K. Murray RK, Granner DK, Mayes PA and Rodwell VW 27th edition, McGraw-Hill Medical Pub., 2006.Lehninger Principles of Biochemistry, Nelson DL and Cox MM, 5th edition, Freeman Pub, 2009.
Biochemistry lecture notebook, Berg JM, Tymoczko JL and Stryer L, 6th edition, Freeman Pub., 2006.
6.4- Periodicals, Web Sites, … etc
http://mic2.shams.edu.eg/moodle www.medicaleducationonline.org www.eul.edu.eg www.wilkpedia.com www.encyclopedia.com
Medical statistics course specificationUniversity: Ain Shams University Faculty: of MedicineCourse specificationsProgram on which the course is given: MSc in Medical Biochemistry and Molecular BiologyMajor or minor element of programs: MinorDepartment offering the program: Medical Biochemistry and Molecular BiologyDepartment offering the course: Community, Environmental and Occupational MedicineAcademic Level: M.Sc. (elective course) Date of specification approval: July, 2009…………………………..
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A- Basic InformationTitle: Medical statistics course Code: E6009Credit Hours: 1 hour CoordinatorCommunity, Environmental and Occupational Medicine Department
B - Professional Information
1- Course Aim:To enable the M.Sc. candidate to plan, conduct, analyze and interpret the results of a research in his specific field. This course unit introduces the application of statistical ideas and methodology to medical research.
2- Intended Learning Outcomes (ILOs) from the Course:
a- Knowledge and understandingBy the end of the course the candidate will be able to:
a1 - Define medical statistics and identify uses and importance of medical statistics in medical researcha2 – Define:
Types of variables.Descriptive statistics.Presentation and summarization of data.Measures of central tendency and scatter.Principles of probability and probability distributions.Concepts of inferential statistics: confidence interval and hypothesis testing.Different tests of statistical significance.Difference between parametric and nonparametric tests of significance.Correlation and regressionConcept of statistical modeling using multivariable and multivariate
statistical methods. Combining evidence from different studies and meta-analysisImportance and methods of sampling and how to determine the suitable
sample size.Different types of research methodology:
Observational and intervention studies and the different statistical issues related to the design, conduct, analysis and interpretation of the results of each study type.
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Ethical aspects of medical research including those specifically applied to clinical trials.
b- Intellectual skillsBy the end of the course the candidate will be able to:
b1 - Interpret correctly the results of statistical analyses and critically evaluate the use of statistics in the medical literature.
b2 - Integrate and evaluate information from a variety of sources.
c- Professional skillsBy the end of the course the candidate will be able to:
c1- Select appropriate study designs to address questions of medical relevance
c2- Select and apply appropriate statistical methods for analyzing data typically encountered in medical applications.
c3- Use selected software packages for statistical analysis and data management.
d- General and transferable skills By the end of the course the candidate will be able to:
d1 - Work effectively in a group from different backgrounds. d2 - Respects the role of staff and co-staff members regardless of degree or
occupation.d3 - Communicate effectively with professional statisticians and the wider
medical community, including the ability to present results of statistical analyses through written and oral presentations
d4 - Use of computer data bases and other computer skills.d5 - Handle data appropriately and analyze them through: decision
processes, objective criteria, problem definition, project design and evaluation, risk management, teamwork and coordination.
d6 - Learn independently with open-mindedness and critical enquiry.
3- Course content: Topics
T C/PIntroduction to medical statistics and its uses 1
Types of variables and Descriptive statistics 1
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Graphic presentation of data 1
Introduction to probability theory and rules 1
Sample and population: sampling distribution of mean and proportion
1
Confidence interval of a mean and a proportion 1
Confidence interval of a difference between two mean /proportion 1
Testing a hypothesis about population mean/proportion 1
Testing a hypothesis about the difference between two means/proportion
1
Comparing between more than two means-Introduction to factorial analysis
1
Cross-tabulation and introduction to categorical data analysis 1
Simple correlation and simple regression 1
Introduction to multivariable and multivariate analysis 1
Study designs: observational studies 1
Study designs: Intervention studies: clinical trials 1
Study designs: Experimental animal studies 1
Study designs: Bias and Confounding 1Ethical issues in medical research 1
Sample size estimation for continuous and binary outcome measures.
1
Meta-analysis and publication bias.
1
T: Tutorial and C/P: Clinical or Practical and SDL: Self directed learning
4 - Student Assessment Methods
49
4-1 Written exam to assess knowledge and understanding and will concentrate on problem solving questions
4-2 Weighing of assessmentWritten exam 50
Total 50
5 - List of References5.1- Course Notes (paper and / or electronic)Student Notes on Medical Statistics and Research Methods. Prof. Mohsen
Abdel Hamid and Dr Moustafa El Houssinie. Department of Community, Environmental and Occupational Medicine.
5.2- Essential Books (Text Books)Statistics in Clinical Practice. avid Coggon. BMJ Books. 2nd edition 20035.3- Recommended BooksHandbook of Epidemiology. Springer 20055.4- Periodicals, Web Sites, etc
www.brettscaife.net/statistics/introstat/ onlinestatbook.com/rvls/ www. Epidemiolog.net http://www.shef.ac.uk/scharr/spss/
Bioinformatics Elective Course Specifications
University: Ain Shams University Faculty: of MedicineProgram on which the course is given: Master degree in Medical biochemistry and Molecular Biology Major or minor element of programs: MinorDepartment offering the program: Medical Biochemistry and Molecular Biology DepartmentDepartment offering the course: Medical biochemistry and Molecular Biology DepartmentAcademic Level: Master – Second part Date of specification approval: July, 2009…………………………..
A- Basic InformationTitle: Medical biochemistry and Molecular Biology course. Code: E6018
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Credit Hours: 1 Lectures: 10Tutorials : Practical:10 Total: 20 hoursCoordinator: Medical Biochemistry and Molecular Biology Department
B- Professional Information1 – Overall Aims of Course
1- To provide a solid understanding of the scope of bioinformatics, the tools and techniques used in its applications and the way to access new information to continue learning
2- To teach students how to examine the structure and function of genes and proteins through the use of computational analysis, statistics, and pattern recognition.
2 – Intended Learning Outcomes of Course (ILOs) a- Knowledge and Understanding: By the end of the course, students should be able to
a1- Understand bioinformatics, the application of computational methods to interpret the rapidly expanding amount of biological information.a2- Describe the range of applications of bioinformatics to molecular biology, clinical medicine, pharmacology, biotechnology, agriculture, forensic science, anthropology and other disciplines.a3- State the role of computers and computer science in the investigations and applications of the data.
c- Intellectual Skills
By the end of the course, students will be able tob1- Understand the language of both experimental biologist and computing scientist, and can bridge the gap between them.b2- Understand how sequence-structure relationships will form the bridge to protein structureb3- Gain to think about solving some health problems through bioinformatics.
d- Professional and Practical Skills By the end of the course, students will be able to
c1- Gain access to the data through the world wide web and use the right methods for their analysis.c2- Retrieve information, and calculate with the data, and extend these skills by self-directed 'field work' on the web.
e- General and Transferable Skills
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By the end of the course, students will be able tod1- Discuss among partners involved in the bioinformatics problems (biologists, statisticians and computer professionals).d2- Use the Web and other resources for gene and protein surveys.
3- ContentsSDL P L Topic
1What is Bioinformatics?
1DNA structure and flow of genetic information
1Regulation of gene expression1Protein structure
11Sequences:Biological DNA and protein sequences, the genetic codeSequence tools
21 Handling sequences in biological databases
21Sequence comparison:Identity, similarity, and homology.
21Pairwise sequence alignment
11Multiple Sequence Alignment
21Microarray
4– Teaching and Learning Methods
4.1- Power point slide presentations.4.2- Practical online training. 4.3- Students presentations.4.4- Open discussions.
5- Student Assessment Methods
52
5.1 Genetic code, translation and mutation exercises to assess their understanding to the basic molecular biology concepts.
5.2 Weblems to assess their ability of doing WWW surveys.5.3 Constructing phylogenetic trees to assess their ability to use
different bioinformatics programs.5.4 Student presentations to assess understanding the basics and ability
to transfer knowledgeable skills.
Weighing of AssessmentsClass discussion participation 5%Homework (exercises, reading assignments) 10%Practical work 10% Individual presentations 15%Final-term Examination 60% Oral Examination. 0%
Total 100%
Any formative only assessments
6- List of References
6.1- Course NotesThe power point presentations.PDF handouts.
6.2- Essential Books (Text Books) Introduction to Bioinformatics by Arthur M. Lesk (2005).
Papers and handouts relevant to presented topics will be distributed as needed.
6.3- Recommended Books Discovering Genomics, Proteomics, and Bioinformatics
by A. Malcolm Campbell, Laurie J. Heyer Introduction to Bioinformatics: A Theoretical and Practical Approach
by Stephen A., Ph.D. Karwetz )Editor(, David D., Ph.D. Womble )Editor(
Bioinformatics For Dummies (For Dummies (Math & Science)) by Jean-Michel Ph. D. Claverie, Cedric Ph.D. Notredame
53
Introduction to Protein Science: Architecture, Function, and Genomics by Arthur M. Lesk
6.4- Periodicals, Web Sites, … etchttp://www.ncbi.nlm.nih.gov/http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=OMIMhttp://www.ensembl.org/index.htmlhttp://www.expasy.org/http://www.bioinformatik.dehttp://post.queensu.ca/~forsdyke/bioinfor.htmhttp://www.techfak.uni-bielefeld.de/bcd/ForAll/Basicshttp://www.dnaftb.org/dnaftb/http://www.perl.com/pub/q/documentationhttp://www.pdg.cnb.uam.es/cursos/FVi2001/GenomAna/GeneIdentification/SearchContent/main.htmlhttp://www.rcsb.orghttp://scop.mrc-lmb.cam.ac.uk/scop/http://www.genebee.msu.su/services/phtree_reduced.htmlhttp://evolution.genetics.washington.edu/phylip/software.htmlhttp://copland.udel.edu/~schmidtc/html/internet_links.html
7- Facilities Required for Teaching and Learning
PCs, Data show, whiteboard and markers, Printer and papers, copying machine, and Internet connection
V- General Information: 1 - Monitoring of Training and Submission of Training Reports:
You must keep proper and updated records in your logbook to reflect the activities encountered in your training. Your logbook must be duly endorsed by an authorized signatory at the end of each semester.
You will be continuously assessed by your supervisors, in consultation with head of department. An assessment will be submitted within 2 weeks of completion of each semester. 2 - Miscellaneous Information:Injury and/or Blood or Body Fluid Exposure: During regular working hours, you should immediately report an exposure incident to --------------------------. If exposure occurs after regular working hours or during a weekend or holiday; please call the ----------------------------------------. For injury, please report to the Emergency Department.
54
Please also be sure to inform the supervisors of an exposure incident and/or injury. 3 - Action Completion of Clinical Training:Once all training sessions are completed the log book should be signed by the senior supervisor and the head of the department and then should be submitted to post graduate secretariat. A hard copy of your logbook summary should be delivered to the department secretariat at the end of each semester.
4- Reference:The Training Guide is available at the post graduate Secretariat and could be downloaded from the following website
!st SemesterTitle: Module 1Codes: Bacteriology &immunology (BM6001a ), Or Pharmacology (BM6001b), Or Physiology (BM6001c) and Practical Biochemistry Course (BM6002) Contents:
Topic Credit hoursBacteriology &immunology Or PharmacologyOr Physiology
4
Practical Biochemistry Course 2
2 nd Semester Title: Module 2Codes: Medical Biochemistery (BM6003), Molecular Biology (BM6004), Credit hours: 6 Lectures: Practical:
Topic Credit hoursMedical Biochemistery 5Molecular Biology 1
3 rd semester: Title: Module 3Codes: Medical Biochemistery (BM6003), Molecular Biology (BM6004), Applied Biochemistry (BM6005),
55
Credit hours: 6 Lectures: Practical: Topic Credit hoursMedical Biochemistery 4Molecular Biology 1Applied Biochemistry 1
4 th semester Title: Module 4 Codes: Medical Biochemistery (BM6003), Molecular Biology (BM6004), Applied Biochemistry (BM6005), Credit hours: 5 Lectures: Practical:
Topic Credit hoursMedical Biochemistery 3Molecular Biology 1Applied Biochemistry 1
Your log book
1- IntroductionThe aim of this book is to give you a guide to the expectations for each
item. It will be a guide for both you and your teachers to what you should be seeing and doing.
It will give you a list of the important topics that you should think about and should be covered in:
1. Clinical or practical sessionsor2. Lecturesor3. Self-directed learning (SDL)
For each item there is also a list of1. Clinical conditions or Practical sessions to be seen or
attended (According to each degree)2. Practical procedures to be seen and done
Remember
This document is only a guide. It is not an exhaustive list. It is not just a checklist to score points. It is a guide to encourage you to read and learn more. This book is for your benefit. It will form a record of your clinical training and experience.
56
2 - Supervisors
………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………3–Tables for Training RecordsRequirementsCandidates are required to fulfill 75% of the listed activities in order to be eligible for the exam entry. The minimum number required for each activity = 75%. You are free to attend more and record your extra attendance.
Weekly Department planWeekly Department PlanDay /time
Saturday Sunday Monday Tuesday Wednesday Thursday
Lectures 9-11 am 9-11 amPracticalSessions
8-10 am
Seminars 11am -1 pm
Journal Club
11am–1 pm
Seminars and journal club are biweekly
Conferences attendance(NB. Minimum number required is 2)
No
Dat
e
Plac
e
Topics Supervisor signature
12
57
Thesis attendance(NB. Minimum number required is 10)
No Date Place Name of the thesis Supervisor
signature12345678910
Journal club attendance(NB. Minimum number required is 8)
No
Dat
e
Plac
e
Topics Supervisor signature
12345678
Seminars attendance(NB. Minimum number required is 10)
No
Dat
e
Plac
e
Topics Supervisor signature
12
58
345678910
Practical skillsPractical skills (Agreement Scale) of
Medical Biochemistry and Molecular Biology
Weighing and preparation of solutions(NB. Minimum number required is 5)
No Date Place Performance Supervisor signature
12345
Buffer preparation(NB. Minimum number required is 5)
No Date Place Performance Supervisor signature
12345
Specimen Collection and processing (NB. Minimum number required is 5)
No Date Place Performance Supervisor
59
signature12345
Spectrophotometric assays(NB. Minimum number required is 6)
No Date Place Performance Supervisor signature
123456
Urine Analysis (NB. Minimum number required is 4)
No Date Place Performance Supervisor signature
1234
Urinary stone analysis(NB. Minimum number required is 2)
No Date Place Performance Supervisor signature
12
60
DNA extraction (NB. Minimum number required is 2)
No Date Place Performance Supervisor signature
12
Electrophoresis(NB. Minimum number required is 2)
No Date Place Performance Supervisor signature
12
AP =ASSISTED PERFORMANCEIP =INDEPENDENT PERFORMANCEO =OBSERVATIONP =POOR S= Satisfactory E= Excellent GOOD
Assignments (NB. Minimum number required is 10)
No Date Score Topic Supervisor signature
1 Assessment of a diabetic case by OGTT
2 Assessment of a dyslipidemic case by spectrophotometry
3 Calculations of concentration and dilution of solutions
4 Preparation and presentation of a seminar (advanced biochemistry and molecular biology)
5 Preparation and presentation of one article in Journal club sessions
6 Design primers for a specific gene7 Check validity of a PCR primer
sequence for a specific gene
61
8 Analyze the results of DNA fingerprinting
5 - Log book previewThe candidate logbook will be reviewed and patients seen/ skills
performed summarized by diagnosis groups during the semester evaluation and at the end of the course in the table below. The results of this review will be totaled in the summary chart below.
Summary
1st Semester
2nd
Semester
3rd Semester
4th Semester
Total
Activity No No No NoConferences attendanceThesis attendanceJournal club attendanceSeminar attendance
Practical skills: Weighing and preparation of solutionsPreparation of buffersSpecimen collection and processingSpectrophotometric assaysUrine analysisUrinary stone analysisDNA extractionElectrophoresis
Assignments:Assessment of a diabetic case by OGTT Assessment of a
62
dyslipidemic case by spectrophotometry Preparation and presentation of a seminar Preparation and presentation of one article in Journal club sessionsDesign PCR primers for a specific geneCheck validity of a PCR primer sequence for a specific geneAnalyze the results of DNA fingerprintingSupervisor signature
VII - Head Of Department Approval For The Exam Entry________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________
VIII – Thesis Follow up/ التاريخ/ لعام السنوى النصف التقرير
/ الطالب عن( ) ماجسيتر لدرجة المقيد/ بقسم
63
المشرفين االساتذة السادة تقرير
و العلمية الم:::::ادة جمعالمقدمة كتابة
شوطا قطعبدأمحدودا
على أوشكاإلنتهاء
من إنتهىالجمع
شوطا قطعبدأالعملى الجزءمحدودا
على أوشكاإلنتهاء
من إنتهىالتحليل
شوطا قطعبدألنتائج ا مناقشةمحدودا
على أوشكاإلنتهاء
من إنتهىالتحرير
مع النهائية المراجعةالمشرف
شوطا قطعبدأمحدودا
على أوشكاإلنتهاء
تماما إنتهت
الس:::::::::::ادة رأىالمشرفين
قيد إس:::::تمرارالطالب
القيد مد
قيد ش::::::::طب الطالب
لجنة تش::::::كيل تم المناقشة
نعم ال
ت:::::::::اريخ التشكيل
/ /
القيد / شطب مدالكلية وكيلالمشرفين السادة توقيع
VIII – Evaluation Forms
To be completed at -------------------------------------
64
Candidate SupervisorLocation
Aim of training ______________________________________________________________________________________________________________________________________________________________________________________________________ Agreed educational objectives and timescale in which objectives should be achieved. ______________________________________________________________________________________________________________________________________________________________________________________________________
Comments by Candidate______________________________________________________________________________________________________________________________________________________________________________________________________
Comments by Supervisor ________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________
Date of next meeting
Signed by candidate
Signed by Supervisor
Date
Degree Program Evaluation Form by The CandidateTo be completed at the end of your degree.
65
Please consider each pair of statements and decide which most clearly reflects your view and tick one box or answer the question.
I. Individual Information1. Are you a graduate of ASU?
yes no to some degree2. Year and semester when studies began:
II. General Questions1. What are the advantages/disadvantages of the general study environment at the University ASU?
2. What were your expectations when you applied to the degree?
3. Do you feel that the degree program prepares you well for your future studies or employment according to the demands and expectations of those institutions?
yes no to some degree
4. Has the time limit of the program (two or three academic years) caused you any difficulties or inconveniences?
yes no to some degree
III. Structure of Degree Program1. Did you receive enough guidance in planning your study schedule in the beginning of the program?
yes no to some degree
2. What were the main difficulties in the planning of your study schedule?
3. What is your general opinion on the structure of the degree program?
66
4. In your opinion, does the degree program offer a good balance of lectures, seminars, conferences, and book exams?
yes no to some degree
a) General Studies
i) Do you feel that you have received enough guidance on academic writing?
yes no to some degree
ii) Do you feel that you have acquired sufficient knowledge on research skills (eg. quantitative and qualitative research methods)?
yes no to some degree
b) Courses
i) Have you had some special difficulties in completing some of the courses? Please specify.
ii) Has there been a sufficient variety of courses offered for your optional studies?
yes no to some degree
iii) Have you received enough guidance for the preparation of your thesis?
yes no to some degree
IV. Concluding Points1. Did the degree program meet your expectations?
yes no to some degree2. What aspects of the degree program do you particularly like?
3. What aspects of the degree program do you particularly dislike?
4. What are your suggestions on how to improve the program?
Thank you!
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