Stock Chemicals-Wito -2018 chemicals-Wito... · 2018-10-18 · 1 1 Stock Chemicals-Wito -2018.10 CAS 104632-25-9 Name Pramipexole dihydrochloride Molecular Formula C 10 H 19 Cl 2

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Stock Chemicals-Wito -2018.10

CAS 104632-25-9

Name Pramipexole dihydrochloride

Molecular Formula C10H19Cl2N3S

Molecular Weight 284.25

Structure

Use Mirapex ER (pramipexole dihydrochloride) is a dopamine agonist used alone or

with other medications to treat Parkinson's disease. Mirapex ER is also used to treat

restless legs syndrome (RLS).

CAS 49763-96-4

Name Stiripentol

Molecular Formula C14H18O3


Structure

Use Stiripentol (marketed as Diacomit by Laboratoires Biocodex) is an anticonvulsant

drug used in the treatment of epilepsy. It is approved for the treatment of Dravet

syndrome, an epilepsy syndrome.

CAS 963-14-4

Name Sulfaethoxypyridazine

Molecular Formula C12H14N4O3S


Structure

Use An antibacterial sulfonamide compound



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2

CAS 612548-45-5

Name Perindopril L-Arginine

Molecular Formula C25H46N6O7


Structure

Use Perindopril L-arginineis is an angiotensin converting enzyme inhibitor for the

treatment of mild to moderate essential hypertension. Combined with amlodipine,

a dihydropyridine calcium channel blocker, is approved by FDA, and market as

Prestalia, is indicated for the treatment of hypertension to lower blood pressure.

CAS 541550-19-0

Name Apilimod



Structure

Use Apilimod is identified as an antiproliferative compound by high-throughput

screening of clinical-stage drugs. Apilimod exhibits exquisite specificity for

phosphatidylinositol-3-phosphate 5-kinase (PIKfyve) lipid kinase and has selective

cytotoxic activity in B-cell non-Hodgkin lymphoma (B-NHL) compared with

normal cells. Apilimod displays nanomolar activity in vitro, and in vivo studies

demonstrate single-agent efficacy as well as synergy with approved B-NHL drugs.

CAS 148849-67-6

Name Ivabradine hydrochloride

Molecular Formula C27H37ClN2O5




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Structure

Use Ivabradine hydrochloride is marketed under the trade name Corlanor among

others, is a medication used for the symptomatic management of stable heart-

related chest pain and heart failure not fully managed by beta blockers.

CAS 68-26-8

Name All trans Retinol

Molecular Formula C20H30O


Structure

Use Retinol, also known as Vitamin A1, is a vitamin found in food and used as a dietary

supplement. Retinol is widely used in cosmetics additives designed for all skin

types. It can help firm skin, decrease lines and wrinkles, even skin tone, soften skin

and delay aging. Retinol is also very good for preventing and healing adult acne.

CAS 116-31-4

Name All trans Retinal

Molecular Formula C20H28O


Structure

Use



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CAS 103129-82-4

Name (S)-Amlodipine



Structure

Use Levamlodipine, also known as levoamlodipine or S-amlodipine is a

pharmacologically active enantiomer of amlodipine. Amlodipine belongs to the

dihydropyridine group of calcium channel blocker used as an antihypertensive and

antianginal agent. Receptor binding studies have shown that out of the two forms

only the (S)-enantiomer of amlodipine binds to and blocks L-type calcium channels

whereas the (R)-enantiomer has no activity on these channels. Levamlodipine is

currently marketed in Russia under the brand name EsCordi Cor (Actavis Pharma)

and in India under the trade names Eslo (Zuventus Healthcare Ltd.), Asomex

(Emcure Pharmaceutical Ltd.), and Espin (Intas Pharmaceuticals Ltd.).

CAS 2062-78-4

Name Pimozide

Molecular Formula C28H29F2N3O


Structure

Use Pimozide is used to treat symptoms of Tourette's syndrome. It is used only for

patients with severe symptoms who cannot take or have not been helped by other

medicines (e.g., haloperidol)

CAS 749-02-0



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Name Spiperone

Molecular Formula C23H26FN3O2


Structure

Use Spiperone (Spiroperidol; brand name: Spiropitan (JP)) is a typical antipsychotic

and research chemical belonging to the butyrophenone chemical class. It is licensed

for clinical use in Japan as a treatment for schizophrenia. Additionally, spiperone

was identified by compound screening to be an activator of Ca2+ activated Cl−

channels (CaCCs), thus a potential target for therapy of cystic fibrosis.

CAS 856676-23-8

Name Choline Fenofibrate

Molecular Formula C22H28ClNO5


Structure

Use Fenofibrate is a third generation fibric acid derivative that is predominantly

administered as monotherapy to decrease elevated low-density lipoprotein

cholesterol, total cholesterol, triglycerides, apolipoprotein B and alternatively to

increase high-density lipoprotein cholesterol in patients diagnosed with primary

hyperlipidemia or mixed dyslipidemia and to reduce triglycerides in patients with

severe hypertriglyceridemia.

CAS 56518-41-3

Name Brodimoprim

Molecular Formula C13H15BrN4O2



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Structure

Use

CAS 51987-99-6

Name 2-(Nicotinamide)-1,3,4-thiadiazole

Molecular Formula C8H6N4OS


Structure

Use

CAS 106266-06-2

Name Risperidone

Molecular Formula C23H27FN4O2


Structure

Use Risperidone, sold under the trade name Risperdal among others, is an antipsychotic

medication. It is mainly used to treat schizophrenia, bipolar disorder, and irritability

in people with autism. It is taken either by mouth or by injection into a muscle. The

injectable version is long acting and lasts for about two weeks.



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CAS 1095-90-5

Name Methadone hydrochloride

Molecular Formula C21H28ClNO


Structure

Use Methadone hydrochloride is a drug used to treat opioid addiction and pain.

CAS 54143-55-4

Name Flecainide

Molecular Formula C17H20F6N2O3


Structure

Use Flecainide acetate is a class Ic antiarrhythmic agent used to prevent and treat

tachyarrhythmias (abnormal fast rhythms of the heart). It is used to treat a variety

of cardiac arrhythmias including paroxysmal atrial fibrillation (episodic irregular

heartbeat originating in the upper chamber of the heart), paroxysmal

supraventricular tachycardia (episodic rapid but regular heartbeat originating in the

atrium), and ventricular tachycardia (rapid rhythms of the lower chambers of the

heart). Flecainide works by regulating the flow of sodium in the heart, causing

prolongation of the cardiac action potential. Flecainide is sold under the trade name

Tambocor (manufactured by 3M pharmaceuticals). Flecainide went off-patent on

February 10, 2004. In addition to being marketed as Tambocor, it is also available

in generic version and under the trade names Almarytm, Apocard, Ecrinal, and

Flécaine.



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CAS 51-43-4

Name (-)-Epinephrine

Molecular Formula C9H13NO3


Structure

Use As a medication, epinephrine is used to treat a number of conditions including

anaphylaxis, cardiac arrest, and superficial bleeding. Inhaled epinephrine may be

used to improve the symptoms of croup. It may also be used for asthma when other

treatments are not effective. It is given intravenously, by injection into a muscle,

by inhalation, or by injection just under the skin.

CAS 123441-03-2

Name (S)-Rivastigmine



Structure

Use Rivastigmine (sold under the trade name Exelon) is a acetylcholinesterase

inhibitor used for the treatment of mild to moderate Alzheimer's disease and

Parkinson's. The drug can be administered orally or via a transdermal patch.

CAS 201341-05-1

Name Tenofovir disoproxil

Molecular Formula C19H30N5O10P



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Structure

Use Tenofovir disoproxil, sold under the trade name Viread among others, is a

medication used to treat chronic hepatitis B and to prevent and treat HIV/AIDS. It

is generally recommended for use with other antiretrovirals. It may be used for

prevention of HIV/AIDS among those at high risk before exposure, and after a

needlestick injury or other potential exposure. It is sold both by itself and together

as emtricitabine/tenofovir and efavirenz/emtricitabine/tenofovir. It does not cure

HIV/AIDS or hepatitis B. It is available by mouth as a tablet or powder.

CAS

Name 7,10,13-triTES-10-deacetylbaccatin III

Molecular Formula C47H78O10Si3


Structure

Use Intermediate for modified 10-deacetylbaccatin III

CAS



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Name 7-O-TES-baccatin III

Molecular Formula C37H52O11Si


Structure

Use Intermediate for modified baccatin III

CAS 120-89-8

Name Parabanic acid



Structure

Use Intermediate for 1-(2-Phenylethyl)imidazolidine-2,4,5-trione and others.

CAS 22059-64-9

Name 1-(3-Methylquinoxalin-2-yl)ethanone

Molecular Formula C11H10N2O




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Structure

Use Intermediate for synthesis of quinoxaline families.

CAS 102625-64-9

Name Pantoprazole sulfide, 6-(difluoromethoxy)-2-(((3,4-dimethoxypyridin-2-

yl)methyl)thio)-1H-benzo[d]imidazole

Molecular Formula C16H15F2N3O3S


Structure

Use Intermediate for synthesis of pantoprazole.

CAS 31431-39-7

Name Mebendazole



Structure

Use Mebendazole (MBZ) is a medication used to treat a number of parasitic worm

infestations. This includes ascariasis, pinworm disease, hookworm infections,

guinea worm infections, hydatid disease, and giardia, among others. It is taken by

mouth.

CAS 183319-69-9



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Name Erlotinib Hydrochloride (Tarceva)



Structure

Use Erlotinib hydrochloride (trade name Tarceva) is a drug used to treat non-small cell

lung cancer, pancreatic cancer and several other types of cancer. It is a receptor

tyrosine kinase inhibitor, which acts on the epidermal growth factor receptor

(EGFR).

CAS 184475-35-2

Name Gefitinib

Molecular Formula C22H24ClFN4O3


Structure

Use Gefitinib (ZD1839) (trade name Iressa) is a drug used for certain breast, lung and

other cancers. Gefitinib is an EGFR inhibitor, like erlotinib, which interrupts

signaling through the epidermal growth factor receptor (EGFR) in target cells.

Therefore, it is only effective in cancers with mutated and overactive EGFR. It is

marketed by AstraZeneca and Teva.

CAS 2647-50-9

Name Flubromazepam

Molecular Formula C15H10BrFN2O




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Structure

Use

CAS 50739-76-9

Name 2-Amino-3,5-dibromo-benzenemethanol

Molecular Formula C7H7Br2NO


Structure

Use Intermediate for synthesis of bromhexine hydrochloride.

CAS 606-00-8

Name Methyl 3,5-Dibromoanthranilate

Molecular Formula C8H7Br2NO2


Structure

Use Intermediate for synthesis of bromhexine hydrochloride.

CAS 608-36-6



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Name meso-2,3-Dibromosuccinic acid

Molecular Formula C4H4Br2O4


Structure

Use

CAS 93-52-7

Name (1,2-Dibromoethyl)benzene

Molecular Formula C8H8Br2


Structure

Use

CAS 6286-30-2

Name α,β-Dibromohydrocinnamic acid

Molecular Formula C9H8Br2O2


Structure

Use

CAS

Name 2,3-dibromo-3-(4-chlorophenyl)propanoic acid

Molecular Formula C9H7Br2ClO2



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Structure

Use

Documents

Stock Chemicals-Wito -2018 chemicals-Wito... · 2018-10-18 · 1 1 Stock Chemicals-Wito -2018.10 CAS 104632-25-9 Name Pramipexole dihydrochloride Molecular Formula C 10 H 19 Cl 2