GFS Chemicals Chromatography Brochure

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  • 1. Specialty ChemicalManufacturing Expertise Since 1928GFS ChemicalsChromatographyProducts2006-2007 PRODUCT CATALOG

2. Products For ChromatographyAnd Material Separation/ PurificationThe GFS tradition of personal Specialty Silicas, Florisil, Ion Exchangeservice and attention to detail Unmodified, 40, 60, 90, andResins (p. 134-135)has attracted the attention of150 Angstrom, GFSelectTM Drierite, Activatedexperts in chromatography grade (page 130), Bio- Carbons, Diatomaceouswho have long seen a need for refinedTM qualified by Earths (page 136) CHROMATOGRAPHYthis type of commitment toRNase, DNase and Protease Specialty Reagents forproblem solving in separation testing. Chromatography (page 137)sciences. Our alignment with Aluminas (Brockmann I: Bio-RefinedTM Productsthe entrepreneurial resources Acidic, Basic, and Neutral); (page 138)of Diazem Corp. (Midland, MI) W. R. Grace silicas (page Royer Anion Exchangehas already provided industry 131-132) Resins and Precious Metalwith practical solutions to Silica Gel Desiccants; Catalysts (page 139)environmental and process Molecular Sieves (page 133)problems. We invite you totalk to us about using this Diazem MCACportfolio of novel technolo- Flow through a Stainlessgies to address your materials Removal of Pt steel Column of anrecovery or separationsfrom a fluid stream aqueous solution of Pt (0.01M) gave capture ofissues (note example at right).0.029g of Pt on 0.3g of media which is 9.9% Pt Custom Modified Silicas forrelative to the mass of the media.Tough SeparationsProblems (page 124)Measurement of the effluent showed less thanDiazem/Dow tailored200ppb Pt at the baselinetechnologies for the effluent. HPLC Solvents (page 126) Macherey-NagelNUCLEOSIL, NUCLEODUR,unmodified spherical andirregular silica gels (page127-130) Plus access to the 27 3645full Macherey-Nagel Line of 0 9 18mL of 0.1M PtTLC and ColumnChromatography Products 3. Silicas for Advanced The VisionThe GFS Connection Separations from DiazemDiazem and the Dow Chemical The GFS commitment to offer Technologies Co. have announced a jointseveral prominent lines of sili- All the chromatographic sili-technology and licensingcas, including Macherey-Nagel cas on the following pages are agreement that will provide and W. R. Grace products, capable of being modified by the bio-tech market with spe- gives separations scientists a technology recently patented cialty chromatographicbroad base of qualified prod- by Diazem Corp. The resultingsorbents and engineeringucts, traceable by lot analysis products frequently allowprocesses. This includes aunder ISO-certification, which chromatographic separationscritical range of state-of-the- may ultimately be enhanced that are unattainable by stan- art separation capabilities by Diazem/Dow technology. dard silica media. This novelsuitable for geometric andYour customized project can silica/silane surface chemistryoptical isomeric molecules, be managed from research toCHROMATOGRAPHY exhibits a utility and, more peptides and proteins. This commercialization with com- importantly, a predictability in technology will impact theplete confidence in the consis- solving real-life problems most challenging issues oftency of quality of the sorbent faced in separation science. analytical and preparativeof your choice. GFS technicalchromatography, and address and product support bothindustry needs from drug dis- help provide a new gateway The Technologycovery to commercialization.to problem solving in cutting- Diazems Dual ZoneTM Materialedge separation sciences. technology uses pore-diffu- sion control silylation with Unique Diazem Products two (or more) silane bonding Despite the customized agents to give selective bond- nature of Diazem products, ing of one chemical composi- GFS offers a selection of C-18 tion on the outer zone of aDiazem modified silicas for porous material and a differ-your consideration. These ent chemical composition oninclude substrates with poly- the inner zone. Each zonemeric/hydrophilic character then has a different chemicaluseful in pharma-biotech sep- reactivity, and the processarations. New Diazem metal also allows for better silanol chelating media are also avail- control. Sorbents tailored via able from GFS. Please check in this technology can separate the alphabetical section under diverse materials, especiallyDiazem. biological substrates, more completely and efficiently than standard separations media. 4. New Diazem CorporationThese resins have also shown Recovery of precious metalsChelation Technologythe ability to remove radioac- Removal of metals that Diazem Corporations new tive radium from a contami- could otherwise interfereChelation adsorbent contin- nated source. The Diazemwith analytical proceduresues to show promise in sever- MCAC phase reduced the Purification of product oral markets. radium levels from 15 picoproduct streamscuries to less than 1 pico Removal or recovery ofThe new materials, referred tocurie. Mercury levels wereorganic and inorganic acidas metal chelation and acidreduced to below ppb levels.contaminantscapture (MCAC) phases, are Separation of proteins,based on the immobilization The MCAC phases are anpeptides, or nucleotidesof hyperbranched macromole- important extension of Removal of anion contami-cules on various supportDiazems unique, proprietarynants such as phosphatesDual ZoneTM Materials CHROMATOGRAPHYmedia. These phases offerthe advantage of effectivelyTechnology. In Dual ZoneTMDiazem Corporation has takenremoving metal cation and Materials, silanes are chemi- classical silane, surface sci-anion contamination fromcally bonded to porous silica ence and polymer chemistrieschemical processes, waste-support media by preciselyand used them in unconven-water discharge, and drinking controlling coverage density, tional ways to address marketwater. In addition, the materi- silanol capture and phase needs. Feel free to contactals are very effective acid polarity. Dual Zone Materials GFS regarding possible appli-scavengers. Applicationscan be chemically tailored to cations of interest to you.include removal of Fe, Co, Ni,achieve a range of separationCu, Zn, Pt, Pd, Pb, and Hg. Ptgradients for a variety of com-removal is carried out at a plex separations.rate up to 20% relative to theweight of the media.Anions can be removed withsimilar efficiency by usingDiazem Anion Capture Phase.The possible uses of thesematerials include: Recovery of transition-metalcomplexes used in homoge-neous catalytic processes Treatment of waste streamsto remove low levels oftoxic anions 5. HPLC & Specialty Solvents GFS has decades of experi- ence with chemical distilla- tions, both organic and inor- ganic. Our growing experience with the Farchan LaboratoriesCHROMATOGRAPHY line of acetylenic and olefinic research intermediates has given us even more insights into the purification of volatile, moisture and temper- Each of our specialty solventscapillary gas chromatography ature sensitive materials. The is carefully analyzed and certi-with electron capture and grades of solvent offered in fied to meet our publishedflame ionization detectors. this catalog cover a full rangespecifications. The quality of of applications and sensitivi- each solvent far exceedsUltra Low Cut-off, Distilled in ties. These include products reagent specifications set by Glass Solvents consistently that are distilled-in-glass or the American Chemical pure solvents for: quartz, and HPLC solventsSociety. Quality is controlled HPLC where the emphasis is on not only by UV Spectro- Gas Chromatography High Performance.photometry, but also by Pesticide Residue Analysis SpectrophotometryMin Assay % (by GLC) Max WaterMax UV Cutoff Max Residue ACETONE 99.70.50%330nm 3ppm ACETONITRILE99.70.02%190nm 3ppm CHLOROFORM99.70.02%245nm 3ppm CYCLOHEXANE 98.50.01%195nm 3ppm DICHLOROMETHANE 99.80.01%233nm 3ppm ETHYL ACETATE 99.60.05%256nm 3ppm ETHYL ETHER 99.50.08%218nm 3ppm FORMIC ACID 88.0N/AN/A 1ppm HEPTANE 99.50.01%200nm 3ppm HEXANE___ 0.01%200nm 3ppm METHANOL99.80.08%205nm 3ppm PENTANE 98.50.01%195nm 3ppm PETROLEUM ETHER ___ 0.02%____3ppm ISOPROPYL ALCOHOL 99.50.10%205nm 3ppm TETRAHYDROFURAN 99.70.03%215nm 3ppm TOLUENE 99.70.03%284nm 3ppm 2,2,4-TRIMETHYLPENTANE99.70.02%210nm 3ppm 6. New Math ForSilica Gel and Chromatography ProductsMACHEREY-NAGEL...90+Years in Products forChromatography Markets.GFS CHEMICALS 70+ YearsServing Analytical andCHROMATOGRAPHYResearch MarketsIt Adds Up...Partners with160+ years of combined expe-rience, just a phone call away.GFS is your gateway to a hostof chromatography productsfrom Macherey-Nagel GmbH, aleader in the development ofmedia and other products forseparation sciences for over90 years. GFS stocks a wideLarger quantities of these their consistent and well-range of M-N unmodifiedmaterials are also available.defined character:media, including such popularPlease let us know how wetrademarked brands ascan help you. High bed stability due toNUCLEOSIL, NUCLEODUR, spherical particle shapePolygosil, and Polygoprep. NUCLEOSIL Products High efficiency due toWhen your needs extend to narrow particle size the Industry Leadermodified silicas, cellulose, and NUCLEOSIL is a group of distributionTLC products derived fromtotally porous spherical sili- High separation perform-the list shown below, GFS cancas, featuring very pure, uni- ance due to optimizedalso provide you with thoseform SiO2 structure distrib- bonding propertiesmaterials in a timely manner. High chemical and uted within a small (10 micronmechanical stability and finer), narrow particlePlease refer to the following High load capacity and size range. Their outstandingtables and the alphabetical recovery rates performance in analytical assection for the core GFS prod- High reproducibility from well as preparative columnucts from Macherey-Nagel. lot to lot chromatography stems from 7. All NUCLEOSIL narrow-poreNUCLEODUR describes aAs the name implies, the dura- pack