Thao giang bai 6 axit nucleic

• 1. Xin knh cho thy c v cc em hc sinh!

2. Bi 6. AXIT NUCLEIC 3. James Watson (ngi M) & Francis Crick (ngi Anh) I. AXIT EOXIRIBONUCLEIC (ADN) 4. M hnh cng b nm 1953 Vi pht minh ny, hai nh khoa hc cng vi Uynkin c trao gii thng Nben nm 1962 5.

• Cu to theo nguyn tc a phn.

• n phn l cc nucleotit.

I. A XIT XIRIB N UCLIC (ADN) 1. Cu trc

• Nguyn tc cu to ca AND?

• n phn ca AND?

6. I. A XIT OXIRIBO N UCLEIC (ADN) Cu to mt nucleotit: Nucleotit c cu trc nh th no?ng exiribz 7. Cu to mt nucleotit :

• Gm 3 thnh phn:

• * ng xiribz (ng C 5 H 10 O 4 ).

• * Nhm phtphat

• * Baz nit(A: Anin, T: Timin,G: Guanin, X: Xitzin).

8. Cu to mt nucleotit :

• * Cc nu ch khc nhau bi baz nit nn tn gi Nu theo tn gi baz nitc 4 loi nu (A, T, G, X)

• * Cc Nu lin ktvi nhau bng lin kit ha tr (photphodieste) to thnh chui polyNu

C my loi nucleotit? Cc nucleotit lin kt vi nhau ntn? 9. 1. Cu trc ADN.

• ADN c my mch?

10. 2. Cu trc ADN

• ADN c cu trc mch kp, i, song song.

• Hai mch n lin kt vi nhau bng lin kt hidro theo NTBS (A lin kt vi T = 2 lkH; G lin kt vi X =3 lkH)

• => A=T; G=X

• ? Lin kt H c vai tr g?

11. ADN a dang va ac thu: bi so lng , thanh phan ,trat t sap xep cua cac Nu ADN va kh bn vng v kh linh hat Nh s lng lin kt hydro cc k ln,nhng li l lin kt yu. 12. Gen la trnh txac nh cua cac nucleotit tren phan t ADNma hoa 1 san pham nhat nh (Protein hay ARN).GEN GEN 13. 2. Cu trc ADN

• * Trong khng gian 2 chui polynuclotitca ADN xon li quanh trc tng tng, to nn xon kp u v ging 1 cu thang xon.

• * Mi bc thang l 1 cp baz lin kt hir theo nguyn tc b sung.

• * Cn tay thang l cc phn t ng v cc nhm photphat.

• * Michu k xon gm 10 cp Nu.

ADN c cu trc khng gian nh th no? 14. 2. Chc nng ca ADN

• Quan sts v cho bit chc nng ca ADN?

15. 2. Chc nng ca ADN

• Lu gi, bo qunv truyn t thng tin di truyn

Hy cho bit c im cu trc ca ADN gip chng thc hin chc nng ditruyn? ADN Phin m ARN Dch m Prtin 16. II.A XITR IBO N UCLEIC (ARN) 1. Cu trc

• Cu trc a phn.

• n phn l ribnu.

• Cu to 1Nu: ng Ribz (ng C 5 H 10 O 5 ); Nhm phtphat; Baz nit (A, U, G, X)

• Gm 4 loi Nu: A,U,G,X

• ARN ch c 1 mch

• ARN ngn hn AND nhiu

So snh cu trc ADN v ARN? 17. II.A XITR IBO N UCLEIC (ARN) C bao nhiu loi ARN?

• tARNmARNrARN

18. II.A XITR IBO N UCLEIC (ARN) Hon thnh PHT sau: Chc nng Cu trc rARN tARN mARN 19. 2.Chc nngcc loi ARN Cu to nn riboxom (Ni tng hp protein) Vn chuyn cc axit amin ti riboxom L khun tng hp Protein Chc nng L chui polynu n, nhiu vng xon kp cc b L chui polynu n, un to 3 thy L chui polynu n thng Cu trc rARN tARN mARN 20. CNG C

• * Tr li cc cu hi trc nghim sau:

• 1. n phn ca axit xiribonucleic l:

• A, U, G, X

• A, U, T, X

• T, G, U, X

• A,T, G, X

21. Cng c

• 2. Nu cu to ADN khc nu cu to nn ARN :

• Axit photphoric

• Baz nito trong ARN l U thay cho T trong ADN

• ng trong ADN l xiribz, trong ARN l ribz

• C b, c

22. CNG C

• 3. Cc Nu trn mt mch lin kt vi nhau bng:

• LK peptit

• Lk Hidro

• Lk photphodieste

• Lk glicozit

23. CNG C

• 4 . Cc Nu trn hai mch lin kt vi nhau bng:

• LK peptit

• Lk Hidro

• c) Lk photphodieste

• d)Lk glicozit

24. Yu cu:

• Lm bi tp cui sch

• Chun b bi mi

25.