2. ?? 3. ? Cancer ? : 1. carcinoma () : 2. sarcoma () : , , , ,
, , 3. melanoma () : melanocyte 4. leukemia () : 5. lymphoma () :
6. myeloma () : . 4. II 5. III 1g = 1 cm= 109 = 30 1 kg = 10 cm=
1012 = 40 1cm . 100 1000 => 6. II 7. (2011) 8. (2011) 9. II
(2011) 10. III (2011) 11. IV (2011) 12. ? etiology ? : unknown!!! :
=>HPV (Human Papilloma Virus type 16/18) => ; , 0,1,6 3 (risk
factor)smoking alcohol diet obesity environmentvirus radiation
genetics etc. 13. ; clinical diagnosis , , ; imaging diagnosisCT,
MRI, X- ray, PET-CT, , , / => ; pathologic diagnosis , 14. ll
PET/CT1. PET CT 2. PET ( ) : F18() PET : CT => 3. CT ( ) : X ray
: ( ) => 4. PET/CT : CT PET 15. III PET/CT 16. IV PET/CT 1.
PET/CT 2. FDG /, 3. 4. PET/CT CT . 17. V PET/CT 18. VI / (Tumor
Marker)1. 2. a. CEA : , , , , ( ) b. AFP : , c. PSA : (, ) d. CA
19-9 : , , e. CA 125 : f. CA 15-3 : 3. , 19. Cancer Staging TNM [ ]
T Stage - Tis Tumor in situ ; , Carcinoma in situ T1 (mucosa)
(submucosa) T2 T3 T4 20. Cancer Staging TNM [ ] N stage N0 N1 N2 4
N3 10 M stage M0 M1 - 21. Cancer Staging TNM [ ] ; T + N + M1 2 3 4
*** 1 / 2 3 4 22. Cancer Staging 4 ????Staging Grouping IV ( 4 ; )
(Terminal stage) . 4 1. 6 2. performance status bed rest 3.
cachexia => . 23. ECOG PS 24. 3 A. (surgery) B. (radiotherapy)
C. (chemotherapy) 3 A. (hormone therapy) B. (immunotherapy) C.
(gene therapy) 25. - a. b. c. a. b. / c. . 26. - a. / b. c. .( ) a.
(5-8) b. . c. 27. Radiotherapy Respiratory Gating System
Radiotherapy - Trilogy YouTubeImage Guided Radiotherapy ( ) 28. -
a. / . b. c. d. => e. 29. I DNA Repair capacity ( , ) () 30.
Fractionation RTx ( ) 31. II 1.1896 RT 2. --- => 3.1950 . 4.1970
CT 3DRT 5.1990 PET/CT targeting 32. III 33. IV 34. V 35. CT
orPET/CT 36. I 2D 1980 X-RAY AP Lat 37. III 3D 1990 CT PET/CT slice
scan summation => volumetric 38. 2DRT vs. 3DRT 39. IMRT ( )
IMRT; Intensity Modulated RT IMRT radiation field voxel
(volume+pixel) voxel , IMRT 3DRT 2DRT 3DRT doctor base IMRT
computer base 40. IMRT - II 41. 2D vs. 3D vs. IMRT 42. 4DRT 4DRT RT
4DRT 43. 4DRT linac-respiration_monitor-radiotherapy-
lung_cancer.mov YouTube mass real-tracking technique 44.
Tomotherapy LINAC+CT (same body) 45. Gamma-Knife 46. Cyberknife 47.
Proton ^^ 100% Target Particle Tx 48. I Artificial Radiation -
x-ray r-ray - - ; LINAC ( ; Linear Aceelerator) - . - Cs , , - - .
49. I 137 ; Cs 1371. 30 (), 70-1002. 28 , .3. : 4. / 5. : 50. III
(1987) 137 ; Cs137 97 10 110 51. II I-131 : Iodine 1311. 82. 3. 52.
53. Quiz & Tip ? ? ( ) ? : 1 Meat ?controversy, but recommend
white meat. 54. Quiz & Tip II ANC ? (Absolute Neutrophil Count)
( ) , (WBC) 4000 10000 (neutrophil) (eosinophil) (basophil)
(lymphocyte) . 40-70% ANC 500 . 55. I a. : DNA b. % c. 3 kill 1 log
1cm = 109 , 1 cycle => 106 cycle 101 . 107 . 6 cycle 56. II : +
: a. : (), ()(), (),() b. : () a+b. (, ) 57. III 58. a. : b. ()- 5
( )- , => - - : / / /-/ / / / 59. (Thyroid cancer) 2011 1 :
unknown, ? : 40 a. papillary type() b. follicular type () c.
medullary type () d. anaplastic type () 60. (Thyroid cancer) =>
: 10 40% : . Treatment1. op(operation) : Tx of choice2. RAI 3. RT
(radiotherapy) : 4. CTx (chemotherapy) : 61. (Lung cancer) 1 : - 4,
- 3, 4 A. NSCLC (Non-Small Cell Lung Cancer) - 75% - SQCC (Squamous
Cell Carcinoma ; ) AdenoCa (adenocarcinoma ; ) Large cell carcinoma
; B. SCLC (Small Cell Lung Cancer) 62. Lung Cancer II NSCLC1. SQCC
, , 2.AdenoCa , . peripheral locaton, m/c3. Large cell Ca ,
peripheral location SCLC , 63. Lung Cancer III ?-> a. b. 25%
NSCLC (Cancer staging)I /II ; III ; IV ; 64. Lung Cancer IV SCLC
(LD ; Limited Disease) ; (ED ; Extensive Disease ) : (Treatment)A.
NSCLC I/II operation, RTx. IIIA operation +/- RTx or CTx. IIIB
RTx+CTx ( ) IV op, RT, CTx 65. Lung Cancer VB. SCLC - LD CTx+RTx ;
standard Tx. ED CTx , RTx. prognosisNSCLC ; I 5 60-80%II 5
40-60%IIIA 30-40%IIIB 10-15%IV 5 5-10% 66. Lung Cancer VISCLC LD 24
4 20% ED 1 2 5% 67. Breast Cancer 1 : !! ( ) 40-50 30-40 10 20
Axillary Lymph nodes. !!! 68. Breast Cancer ??? . ; , , , mass 80%
fibroadenoma ! 69. Breast Cancer mammogram ! Treatment 1. early
breast cancer ; Breast conserving surgery+ RTx 2. advanced stage ;
MRM ( )+/- RTx. 3. Hormone Tx : ( 5 )=> Tamoxifen 70. ?? . 71.
Positivity & smile => !!!
